메뉴 건너뛰기




Volumn 314, Issue 7076, 1997, Pages 266-

Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPROMAZINE; HALOPERIDOL; NEUROLEPTIC AGENT; PROMAZINE; THIORIDAZINE;

EID: 0031014243     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.314.7076.266     Document Type: Article
Times cited : (248)

References (43)
  • 1
    • 0023693309 scopus 로고
    • Psychosis, behavioral disturbance, and the use of neuroleptics in dementia
    • Devanand DP, Sackeim HA, Mayeux R. Psychosis, behavioral disturbance, and the use of neuroleptics in dementia. Compr Psychiatry 1988; 29: 387–401.
    • (1988) Compr Psychiatry , vol.29 , pp. 387-401
    • Devanand, D.P.1    Sackeim, H.A.2    Mayeux, R.3
  • 2
    • 0025287332 scopus 로고
    • A meta-analysis of controlled trials of neuroleptic treatment in dementia
    • Schneider LS, Pollock VE, Lyness SA. A meta-analysis of controlled trials of neuroleptic treatment in dementia. J Am Geriatr Soc 1990; 38: 553–63.
    • (1990) J Am Geriatr Soc , vol.38 , pp. 553-563
    • Schneider, L.S.1    Pollock, V.E.2    Lyness, S.A.3
  • 3
    • 0026702734 scopus 로고
    • A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia
    • Nyth AL, Gottfries CG, Lyby K, Smedegaard-Andersen L, Gylding-Sabroe J, Kristensen M, et al A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand 1992; 86: 138–45.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 138-145
    • Nyth, A.L.1    Gottfries, C.G.2    Lyby, K.3    Smedegaard-Andersen, L.4    Gylding-Sabroe, J.5    Kristensen, M.6
  • 4
    • 0026773799 scopus 로고
    • Non-neuroleptic treatment of behavioral symptoms and agitation in Alzheimer's disease and other dementia
    • Schneider LS, Sobin PB. Non-neuroleptic treatment of behavioral symptoms and agitation in Alzheimer's disease and other dementia. Psychopharmacol Bull 1992; 28: 71–79.
    • (1992) Psychopharmacol Bull , vol.28 , pp. 71-79
    • Schneider, L.S.1    Sobin, P.B.2
  • 5
    • 0026486988 scopus 로고
    • Non-neuroleptic treatment of disruptive behavior in organic mental syndromes
    • Smith DA, Perry PJ. Non-neuroleptic treatment of disruptive behavior in organic mental syndromes. Ann Pharmacother 1992; 26: 1400–1408.
    • (1992) Ann Pharmacother , vol.26 , pp. 1400-1408
    • Smith, D.A.1    Perry, P.J.2
  • 6
    • 0021743006 scopus 로고
    • A comparison of the prescriptions received by the elderly in long-term care in New York and London
    • Mann AH, Jenkins R, Cross PS, Gurland BJ. A comparison of the prescriptions received by the elderly in long-term care in New York and London. Psychol Med 1984; 14: 891–897.
    • (1984) Psychol Med , vol.14 , pp. 891-897
    • Mann, A.H.1    Jenkins, R.2    Cross, P.S.3    Gurland, B.J.4
  • 7
    • 0021064984 scopus 로고
    • Patterns of neuroleptic use among the institutionalised elderly
    • Gilleard CJ, Morgan K, Wade BE. Patterns of neuroleptic use among the institutionalised elderly. Acta Psychiatr Scand 1983; 68: 419–25.
    • (1983) Acta Psychiatr Scand , vol.68 , pp. 419-425
    • Gilleard, C.J.1    Morgan, K.2    Wade, B.E.3
  • 8
    • 0026754795 scopus 로고
    • The impact of OBRA on medical practice within nursing facilities
    • Elon R, Pawlson LG. The impact of OBRA on medical practice within nursing facilities. J Am Geriatr Soc 1992; 40: 958–63.
    • (1992) J Am Geriatr Soc , vol.40 , pp. 958-963
    • Elon, R.1    Pawlson, L.G.2
  • 9
    • 0029962179 scopus 로고    scopus 로고
    • Survey of neuroleptic prescribing in residents of nursing homes in Glasgow
    • McGrath AM, Jackson GA. Survey of neuroleptic prescribing in residents of nursing homes in Glasgow. BMJ 1996; 312: 611–612.
    • (1996) BMJ , vol.312 , pp. 611-612
    • McGrath, A.M.1    Jackson, G.A.2
  • 10
    • 0019766948 scopus 로고
    • A double-blind comparison of the effects of haloperidol and cis(Z)-clopenthixol in senile dementia
    • Gotestam KG, Ljunghall S, Olsson B. A double-blind comparison of the effects of haloperidol and cis(Z)-clopenthixol in senile dementia. Acta Psychiatr Scand Suppl 1981; 294: 46–53.
    • (1981) Acta Psychiatr Scand Suppl , vol.294 , pp. 46-53
    • Gotestam, K.G.1    Ljunghall, S.2    Olsson, B.3
  • 11
    • 0000233463 scopus 로고
    • The use of trifluoperazine in geriatric patients with chronic organic brain syndrome
    • Hamilton LD, Bennett JL. The use of trifluoperazine in geriatric patients with chronic organic brain syndrome. J Am Geriatr Soc 1962; 10: 140–147.
    • (1962) J Am Geriatr Soc , vol.10 , pp. 140-147
    • Hamilton, L.D.1    Bennett, J.L.2
  • 12
    • 85047575810 scopus 로고
    • Unnecessary use of tranquillisers in elderly patients
    • Barton R, Hurst L. Unnecessary use of tranquillisers in elderly patients. Br J Psychiatry 1966; 112: 2036–42.
    • (1966) Br J Psychiatry , vol.112 , pp. 2036-2042
    • Barton, R.1    Hurst, L.2
  • 16
    • 0018666675 scopus 로고
    • Double-blind study of thioridazine and haloperidol in geriatric patients with a psychosis associated with organic brain syndrome
    • Cowley LM, Glen RS. Double-blind study of thioridazine and haloperidol in geriatric patients with a psychosis associated with organic brain syndrome. J Clin Psychiatry 1979; 40: 411–419.
    • (1979) J Clin Psychiatry , vol.40 , pp. 411-419
    • Cowley, L.M.1    Glen, R.S.2
  • 17
    • 0019988085 scopus 로고
    • Efficacy of antipsychotic medications in behaviorally disturbed dementia patients
    • Barnes R, Veith R, Okimoto J, Raskind M, Gumbrecht G. Efficacy of antipsychotic medications in behaviorally disturbed dementia patients. Am J Psychiatry 1982; 139: 1170–1174.
    • (1982) Am J Psychiatry , vol.139 , pp. 1170-1174
    • Barnes, R.1    Veith, R.2    Okimoto, J.3    Raskind, M.4    Gumbrecht, G.5
  • 19
    • 0014798862 scopus 로고
    • Clinical evaluation of haloperidol in geriatric patients
    • Tobin JM, Brousseau ER, Lorenz AA. Clinical evaluation of haloperidol in geriatric patients. Geriatrics 1970; 25: 119–22.
    • (1970) Geriatrics , vol.25 , pp. 119-122
    • Tobin, J.M.1    Brousseau, E.R.2    Lorenz, A.A.3
  • 20
    • 0016268943 scopus 로고
    • Haloperidol versus thioridazine for the treatment of psychogeriatric patients: a double-blind clinical trial
    • Smith GR, Taylor CW, Linkous P. Haloperidol versus thioridazine for the treatment of psychogeriatric patients: a double-blind clinical trial. Psychosomatics 1974; 15: 134–138.
    • (1974) Psychosomatics , vol.15 , pp. 134-138
    • Smith, G.R.1    Taylor, C.W.2    Linkous, P.3
  • 21
    • 0014101375 scopus 로고
    • Comparative pharmacotherapy of the aging psychotic patient
    • Lehmann HE, Ban TA. Comparative pharmacotherapy of the aging psychotic patient Laval Med 1967; 38: 588–95.
    • (1967) Laval Med , vol.38 , pp. 588-595
    • Lehmann, H.E.1    Ban, T.A.2
  • 22
    • 0018345783 scopus 로고
    • Double-blind comparison of haloperidol and thioridazine in geriatric outpatients
    • Rosen JH. Double-blind comparison of haloperidol and thioridazine in geriatric outpatients. J Clin Psychiatry 1979; 40: 17–20.
    • (1979) J Clin Psychiatry , vol.40 , pp. 17-20
    • Rosen, J.H.1
  • 23
    • 0024382616 scopus 로고
    • A pilot study of haloperidol treatment of psychosis and behavioral disturbance in Alzheimer's disease
    • Devanand DP, Sackeim HA, Brown RP, Mayeux R. A pilot study of haloperidol treatment of psychosis and behavioral disturbance in Alzheimer's disease. Arch Neurol 1989; 46: 854–857.
    • (1989) Arch Neurol , vol.46 , pp. 854-857
    • Devanand, D.P.1    Sackeim, H.A.2    Brown, R.P.3    Mayeux, R.4
  • 24
    • 0028061589 scopus 로고
    • Utility of extrapyramidal signs and psychosis as predictors of cognitive and functional decline, nursing home admission, and death in Alzheimer's disease: prospective analyses from the predictors study
    • Stern Y, Albert M, Brandt J, Jacobs DM, Tang MX, Marder K, et al. Utility of extrapyramidal signs and psychosis as predictors of cognitive and functional decline, nursing home admission, and death in Alzheimer's disease: prospective analyses from the predictors study. Neurology 1994; 44: 2300–2307.
    • (1994) Neurology , vol.44 , pp. 2300-2307
    • Stern, Y.1    Albert, M.2    Brandt, J.3    Jacobs, D.M.4    Tang, M.X.5    Marder, K.6
  • 25
    • 0021882237 scopus 로고
    • Heterogeneity in dementia of the Alzheimer type. Evidence of subgroups
    • Mayeux R, Stern Y, Spanton S. Heterogeneity in dementia of the Alzheimer type. Evidence of subgroups. Neurology 1985; 35: 453–61.
    • (1985) Neurology , vol.35 , pp. 453-461
    • Mayeux, R.1    Stern, Y.2    Spanton, S.3
  • 26
    • 0024578269 scopus 로고
    • Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type
    • Drevets WC, Rubin EH. Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type. Biol Psychiatry 1989; 25: 39–48.
    • (1989) Biol Psychiatry , vol.25 , pp. 39-48
    • Drevets, W.C.1    Rubin, E.H.2
  • 27
    • 0025891118 scopus 로고
    • Emergence of psychosis and depression in the longitudinal evaluation of Alzheimer's disease
    • Rosen J, Zubenko GS. Emergence of psychosis and depression in the longitudinal evaluation of Alzheimer's disease. Biol Psychiatry 1991; 29: 224–32.
    • (1991) Biol Psychiatry , vol.29 , pp. 224-232
    • Rosen, J.1    Zubenko, G.S.2
  • 28
    • 0025336614 scopus 로고
    • Psychiatric phenomena in Alzheimer's disease. II: Disorders of perception
    • Burns A, Jacoby R, Levy R. Psychiatric phenomena in Alzheimer's disease. II: Disorders of perception Br J Psychiatry 1990; 157: 76–81.
    • (1990) Br J Psychiatry , vol.157 , pp. 76-81
    • Burns, A.1    Jacoby, R.2    Levy, R.3
  • 29
    • 0028352254 scopus 로고
    • Extrapyramidal signs and psychiatric symptoms predict faster cognitive decline in Alzheimer's disease
    • Chui HC, Lyness SA, Sobel E, Schneider LS. Extrapyramidal signs and psychiatric symptoms predict faster cognitive decline in Alzheimer's disease. Arch Neurol 1994; 51: 676–81.
    • (1994) Arch Neurol , vol.51 , pp. 676-681
    • Chui, H.C.1    Lyness, S.A.2    Sobel, E.3    Schneider, L.S.4
  • 30
    • 0027243816 scopus 로고
    • Psychotic features and the course of Alzheimer's disease: relationship to cognitive, electroencephalographic and computerised tomography findings
    • Förstl H, Besthorn C, Geiger-Kabisch C, Sattel H, Scheiter-Gasser U. Psychotic features and the course of Alzheimer's disease: relationship to cognitive, electroencephalographic and computerised tomography findings. Acta Psychiatr Scand 1993; 87: 395–399.
    • (1993) Acta Psychiatr Scand , vol.87 , pp. 395-399
    • Förstl, H.1    Besthorn, C.2    Geiger-Kabisch, C.3    Sattel, H.4    Scheiter-Gasser, U.5
  • 31
    • 0026784959 scopus 로고
    • Predictors of cognitive and functional progression in patients with probable Alzheimer's disease
    • Mortimer JA, Ebbitt B, Jun S, Finch M. Predictors of cognitive and functional progression in patients with probable Alzheimer's disease. Neurology 1992; 42: 1689–96.
    • (1992) Neurology , vol.42 , pp. 1689-1696
    • Mortimer, J.A.1    Ebbitt, B.2    Jun, S.3    Finch, M.4
  • 32
    • 0026532438 scopus 로고
    • The present behavioural examination (PBE): the development of an interview to measure current behavioural abnormalities
    • Hope T, Fairburn CG. The present behavioural examination (PBE): the development of an interview to measure current behavioural abnormalities. Psychol Med 1992; 22: 223–30.
    • (1992) Psychol Med , vol.22 , pp. 223-230
    • Hope, T.1    Fairburn, C.G.2
  • 34
    • 0000566524 scopus 로고
    • Neuroleptic equivalence
    • Foster P. Neuroleptic equivalence. Pharm J 1989;243;431–2.
    • (1989) Pharm J , vol.243 , pp. 431-432
    • Foster, P.1
  • 35
    • 0026712415 scopus 로고
    • Neuroleptic sensitivity in patients with senile dementia of Lewy body type
    • McKeith I, Fairbairn A, Perry R, Thompson P, Perry E. Neuroleptic sensitivity in patients with senile dementia of Lewy body type. BMJ 1992; 305: 673–678.
    • (1992) BMJ , vol.305 , pp. 673-678
    • McKeith, I.1    Fairbairn, A.2    Perry, R.3    Thompson, P.4    Perry, E.5
  • 36
    • 0027980815 scopus 로고
    • Clinical-neuropathological correlations in Alzheimer's disease and related dementias
    • Galasko D, Hansen LA, Katzman R, Wiederholt W, Masliah E, Terry R, et al. Clinical-neuropathological correlations in Alzheimer's disease and related dementias. Arch Neurol 1994; 51: 888–95.
    • (1994) Arch Neurol , vol.51 , pp. 888-895
    • Galasko, D.1    Hansen, L.A.2    Katzman, R.3    Wiederholt, W.4    Masliah, E.5    Terry, R.6
  • 37
    • 0015965912 scopus 로고
    • Human memory and the cholinergic system: a relationship to aging?
    • Drachman DA, Leavitt JB. Human memory and the cholinergic system: a relationship to aging? Arch Neurol 1974; 30: 113–21.
    • (1974) Arch Neurol , vol.30 , pp. 113-121
    • Drachman, D.A.1    Leavitt, J.B.2
  • 38
    • 0002375175 scopus 로고
    • Neuropathologic findings after neuroleptic long-term therapy
    • In: Roizin L, Shiraki H, Grcevic N, eds New York Raven Press
    • Jellinger K. Neuropathologic findings after neuroleptic long-term therapy. In: Roizin L, Shiraki H, Grcevic N, eds. Neurotoxicology. New York: Raven Press, 1977: 25–42.
    • (1977) Neurotoxicology , pp. 25-42
    • Jellinger, K.1
  • 39
    • 0028141509 scopus 로고
    • Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs
    • Chakos MH, Lieberman JA, Bilder RM, Borenstein M, Lerner G, Bogerts B, et al Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. Am J Psychiatry 1994; 151: 1430–1436.
    • (1994) Am J Psychiatry , vol.151 , pp. 1430-1436
    • Chakos, M.H.1    Lieberman, J.A.2    Bilder, R.M.3    Borenstein, M.4    Lerner, G.5    Bogerts, B.6
  • 42
    • 0029874311 scopus 로고    scopus 로고
    • Presynaptic serotonergic markers in community-acquired cases of Alzheimer's disease: correlations with depression and neuroleptic medication
    • Chen CP, Alder JT, Bowen DM, Esiri MM, McDonald B, Hope T, et al. Presynaptic serotonergic markers in community-acquired cases of Alzheimer's disease: correlations with depression and neuroleptic medication. J Neurochem 1996; 66: 1592–1598.
    • (1996) J Neurochem , vol.66 , pp. 1592-1598
    • Chen, C.P.1    Alder, J.T.2    Bowen, D.M.3    Esiri, M.M.4    McDonald, B.5    Hope, T.6
  • 43
    • 0029788310 scopus 로고    scopus 로고
    • The basis for behavioural disturbances in dementia
    • Esiri MM. The basis for behavioural disturbances in dementia. J Neurol Neurosurg Psychiatry 1996; 61: 127–30.
    • (1996) J Neurol Neurosurg Psychiatry , vol.61 , pp. 127-130
    • Esiri, M.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.