Antimutagenic effects of black tea (World blend) and its two active polyphenols theaflavins and thearubigins in Salmonella assays

Phytotherapy Research

Volumn 16, Issue 7, 2002, Pages 655-661

  Gupta, S ^a   Chaudhuri, T ^a   Seth, P ^a   Ganguly, D K ^a   Giri, A K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Antimutagenicity assay; Black tea (world blend); In vitro; Salmonella

Indexed keywords

2 FLUORENYLAMINE; 4 NITRO 1,2 PHENYLENEDIAMINE; DANTRON; HYDROPEROXIDE; MUTAGENIC AGENT; PLANT EXTRACT; POLYPHENOL DERIVATIVE; SODIUM AZIDE; THEAFLAVIN; THEARUBIGIN; UNCLASSIFIED DRUG;

AMES TEST; ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BACTERIUM COLONY; CONCENTRATION RESPONSE; CONTROLLED STUDY; MALE; NONHUMAN; PHYTOCHEMISTRY; RAT; TEA;

ANIMALS; ANTIMUTAGENIC AGENTS; BIFLAVONOIDS; CATECHIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; MALE; MUTAGENICITY TESTS; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; POLYMERS; RATS; SALMONELLA; TEA;

BACTERIA (MICROORGANISMS); CAMELLIA SINENSIS; SALMONELLA;

EID: 0036847443     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1038     Document Type: Article

References (47)

1. Ames BN, Durston WE, Yamasaki E, Lee FD. 1973. Carcinogens are mutagens: A simple test system combining liver homogenates for activation and bacteria for detection. Proc Natl Acad Sci USA 70: 2081-2285.
2. Apostolides Z, Balentine DA, Harbowy ME, Weisburger JH. 1996. Inhibition of 2-amino-1methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) mutagenicity of black and green tea extracts and polyphenols. Mutat Res 359: 159-163.
3. Apostolides Z, Balentine DA, Harbowy ME, Hara Y, Weisburger JH. 1997. Inhibition of PHIP mutagenicity by catechins and by theaflavins and gallate esters. Mutat Res 371:167-172.
4. Bu-Abbas A, Nunez X, Clifford MN, Walker R, Ioannides C. 1996. A comparison of the antimutagenic potential of green, black and decaffeinated teas: Contribution of flavonols to the antimutagenic effect. Mutagenesis 11: 597-603.
5. Catteral F, Copeland E, Clifford MN, Ioannides C. 1998. Contribution of theafulvins to the antimutagenicity of black tea: Their mechanism of action. Mutagenesis 13: 631-636.
6. Chaudhuri L, Basu S, Seth P et al. 2000. Prokinetic effect of black tea on gastrointestinal motility. Life Sci: 66: 847-854.
7. Constable A, Varga N, Richoz J, Stadler RH. 1996. Antimutagenicity and catechin content of soluble instant teas. Mutagenesis 11: 189-194.
8. Chen HY, Yen GC. 1997. Possible mechanisms of antimutagens by various tea as judged by their effects on mutagenesis by 2-amino-3-methylimidazo[4,5-f] quinoline and benzo[a]pyrene. Mutat Res 393: 115-122.
9. Dunnett CW. 1955. A multiple comparison procedure for comparing several treatments with the control. J Am Stat Assoc 50: 1096-1121.
10. Garner RC, Miller EC, Miller JA. 1972. Liver microsomal metabolism of aflatoxin B1 to a reactive derivative toxic to Salmonella typhimurium TA1530. Cancer Res 32: 2058-2066.
11. Giri AK. 1996. Genetic toxicology of four commonly used benzodiazepines: A review. Mutat Res 340: 93-108.
12. Giri AK, Mukhopadhyay A, Sun J, Hsie AW, Ray S. 1999. Antimutagenic effects of centchroman - A contraceptive and a candidate drug for breast cancer in multiple mutational assays. Mutagenesis 14: 613-619.
13. Goldbohm RA, Hertog MG, Brants HA, van Poppel G, van den Brandt PA. 1996. Consumption of black tea and cancer risk a prospective cohort study. J Natl Cancer Inst 88: 93-100.
14. Green RH. 1949. Inhibition of multiplication of influenza virus by extracts of tea. Proc Soc Expl Biol Med 71: 84-85.
15. Gupta S, Mukhopadhyay A, Roy S, Giri AK. 1999. Comparative antimutagenic effects of D- and I-centchroman and their comparison with tamoxifen in Salmonella assay. Mutat Res 445: 1-8.
16. Hasaniya N, Youn K, Xu M, Hernaez J, Dashwood RH. 1997. Inhibitory activity of green and black tea in a free radical generating system using 2-amino-3-methylimidazo[4,5b] quinoline as substrate. J Cancer Res 88: 553-558.
17. Hernaez J, Xu M, Dashwood R. 1997. Effects of tea and chlorophyllin on the mutagenicity of N-hydroxy-IQ: Studies of enzyme inhibition, molecular complex formation, and degradation/scavenging of the active metabolites. Environ Mol Mutagen:30: 468-474.
18. Hernaez JF, Xu M, Dashwood RH. 1998. Antimutagenic activity of tea towards 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline effect of tea concentration and brew time on electrophile scavenging. Mutat Res 402: 299-306.
19. Ikigi H, Toda M, Okubo S, Hara Y, Shimamura T. 1990. Relationship between the anti-hemolysin activity and the structure of catechins and theaflavins (in Japanese). J J Bacteriol 45: 913-919.
20. Imanishi H, Sasaki Yu F, Ohta T, Watanabe M, Kato T, Shirasu Y. 1991. Tea tannin components modify the induction of sister chromatid exchanges and chromosome aberrations in mutagen-treated cultured mammalian cells and mice. Mutat Res 259: 79-87.
21. Katiyar SK, Mukhtar H. 1996. Tea in chemoprevention of cancer: Epidemiological experimental studies (review). Int J Oncol 8: 221-238.
22. Kato R. 1986. Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates. Crit Rev Toxicol 16: 307-348.
23. Kennedy DO, Nishimura S, Hasuma T, Yano Y, Otani S, Matsui-Yuasa I. 1998. Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro. Chem Biol Interact 110: 159-172.
24. Kono S, Ikeda M, Tokudome S, Kuratsume M. 1988. A case control study of gastric cancer and diet in Northern Kyushu, Japan. Jpn J Cancer Res 79: 1067-1074.
25. Kuroda Y. 1996. Bio-antimutagenic activity of green tea catechins in cultured Chinese hamster V79 cells. Mutat Res 361: 179-186.
26. Kuroda Y, Hara Y. 1999. Antimutagenic and anticarcinogenic activity of tea polyphenols. Mutat Res 436: 69-97.
27. Lee IP, Kim YH, Kang MH, Roberts C, Shim JS, Roh JK. 1997. Chemopreventive effect of green tea (Camellia sinensis) against cigarette smoke induced mutation (SCE) in humans. J Cell Biochem (Suppl) 27: 68-75.
28. Levin DE, Hollstein MC, Chirstrnan MF, Schwiers EA, Ames BN. 1982. A new Salmonella strain (TA102) with A: T base pair at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci USA 79: 7445-7449.
29. Maron DM, Ames BN. 1983. Revised methods for the Salmonella mutagenicity test. Mutat Res 113: 173-215.
30. Matsuzaki T, Hara Y. 1985. Antioxidative activity of tea leaf catechins (in Japanese). Nippon Kogeikagaku Kaishi 59: 129-134.
31. Nagabhusan M, Amonkar AJ, Nair UJ et al. 1988. Catechin as antimutagen: Its mode of action. J Cancer Res Clin Oncol 114:177-182.
32. Nakayama M, Toda M, Okubo S, Shimamura T. 1990. Inhibition of influenza virus infection by tea. Lett Appl Microbiol 11: 38-40.
33. Oguni L, Nasu K, Yamamoto S, Nomura T. 1988. On the antitumor activity of fresh green tea leaf. Agri Biol Chem 52:1879-1880.
34. Okubo S, Ikigai H, Toda M, Shimamura T. 1989. The antihaemolysin activity of tea and coffee. Lett Appl Microbiol 9: 65-66.
35. Okubo S, Toda M, Hara Y, Shimamura T. 1991. Antifungal and fungicidal activities of tea extract and catechin against Trichophyton (in Japanese). Jpn J Bacteriol 46: 509-514.
36. Okuda T, Mori K, Hayatsu H. 1984. Inhibitory effect of tannins on direct acting mutagens. Chem Pharmacol Bull 32: 3755-3758.
37. Prestera T, Zhang Y, Spencer SR, Wilezak, Talalay P. 1993. The electrophile counterattack response: Protection against neoplasia and toxicity. Adv Enzyme Regul 33: 281-296.
38. Roberts EAH. 1962. The Chemistry of Flavonoid Compounds, Geissman (ed.), MacMillan Co., New York: 468-512.
39. Rogers AE, Hafer LJ, Iskander YS, Yang S. 1998. Black tea and mammary gland carcinogenesis by 7,12- dimethylbenz [a]anthracene in rats fed control or high fat diets. Carcinogenesis 7: 1269-1273.
40. Shiraki M, Hara Y, Osawa T, Kumon H, Nakayama T, Kawakishi S. 1994. Antioxidative and antimutagenic effects of theaflavins from black tea. Mutat Res 323: 29-34.
41. Toda M, Okubo S, Hiyoshi R, Shimamura T. 1989. The bacteriocidal activity of tea and coffee. Lett Appl Microbiol 8: 123-125.
42. Toda M, Okubo S, Ikigi H, Suzuki T, Suzuki Y, Shimamura T. 1991. The protective activity of tea against infection by Vibrio cholerae 01. J Appl Bacteriol 70: 109-112.
43. Vuolo LL, Schuessler GJ. 1985. Protein pyrolysate products. Environ Mutagen 7: 577-598.
44. Weisburger JH, Hara Y, Dolan L, Luo FQ, Pittman B, Zang E. 1996. Tea polyphenols as inhibitors of major classes of carcinogens. Mutat Res 371: 57-63.
45. Xie B, Shi H, Chen Q, Ho CT. 1993. Antioxidant properties of fractions and polyphenol constituents from green, oolong and black teas. Proc Natl Sci Council Rep of China 17: 77-84.
46. Yang CS, Lee MJ, Chen L, Yang GY. 1997. Polyphenols as inhibitors of carcinogenesis. Environ Health Perspect 105(Suppl 4): 971-976.
47. Yen GC, Chen HY. 1996. Relationship between antimutagenic activity and major components of various teas. Mutagenesis 11: 37-41.