Sphingomyelinase and ceramide analogs induce contraction and rises in [Ca2+](i) in canine cerebral vascular muscle

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 278, Issue 5 47-5, 2000, Pages

  Zheng, Tao ^a   Li, Wenyan ^a   Wang, Jun ^b   Altura, Bella T ^a,b   Altura, Burton M ^a,b  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b SUNY Downstate Medical Center   (United States)

Author keywords

Cerebral vascular tone; Intracellular calcium; Signal transduction; Smooth muscle contraction; Sphingolipids

Indexed keywords

CERAMIDE; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; BRAIN BLOOD VESSEL; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; DOG; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

EID: 0034042058     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.278.5.h1421     Document Type: Article

References (41)

1. 2+ release in cerebral arteries. Pharmacol Ther 64: 493-507, 1994.
2. Alborch E, Salom JB, and Torregrosa G. Calcium channels in cerebral arteries. Pharmacol Ther 68: 1-34, 1995.
3. Altura BM and Altura BT. Differential effects of substrate depletion on drug-induced concentrations of rabbit aorta. Am J Physiol 219: 1698-1705, 1970.
4. Altura BM and Altura BT. Withdrawal of magnesium causes vasospasm while elevated magnesium produces relaxations of tone in cerebral arteries. Neurosci Lett 20: 323-327, 1980.
5. Altura BM and Altura BT. Magnesium and cardiovascular biology: an important link between cardiovascular risk factors and atherogenesis. Cell Mol Biol Res 41: 347-360, 1995.
6. Augé N, Andrieu N, Nègre-Salvayre A, Thiers J-C, Levade T, and Salvayre R. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation. J Biol Chem 271: 19251-19255, 1996.
7. Augé N, Escargueil-Blanc I, Lajoie-Mazenc I, Suc I, Andrieu-Abadie N, Pieraggi M-T, Chatelut M, Thiers J-C, Jaffrezou JP, Laurent G, Levade T, Nègre-Salvayre A, and Salvayre R. Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein. J Biol Chem 273: 12893-12900, 1998.
8. Ballou LR, Sphingolipids and cell function, Immunol Today 13: 339-341, 1992.
9. Chatterzee, S. Neutral sphingomyelinase. Adv Lipid Res 26: 25-48, 1993.
10. Chatterzee S. Sphingolipids in atherosclerosis and vascular biology. Arterioscler Thromb Vasc Biol 18: 1523-1533, 1998.
11. Dressler KA and Kolesnick RN. Ceramide-1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. J Biol Chem 265: 14917-14921, 1990.
12. Hannun YA. The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269: 3125-3128, 1994.
13. Hannun YA. Functions of ceramide in coordinating cellular responses to stress. Science 274: 1855-1859, 1996.
14. Hannun YA and Bell RM. The sphingomyelin cycle: a prototypic sphingolipid signaling pathway. Adv Lipid Res 25: 27-40, 1993.
15. He GQ, Zhang A, Altura BT, and Altura BM. Cocaine-induced cerebrovasospasm and its mechanism of action. J Pharmacol Exp Ther 268: 1532-1539, 1994.
16. Jones MJ and Murry AW. Evidence that ceramide selectively inhibits protein kinase C-α translocation and modulates bradykinin activation of phospholipase D. J Biol Chem 270: 5007-5013, 1995.
17. Kim M-Y, Linardic C, Obeid L, and Hannun Y. Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α and γ-interferon. J Biol Chem 266: 484-489, 1991.
18. Kolesnick R. Signal transduction through the sphingomyelin pathway. Mol Chem Neuropathol 21: 287-297, 1994.
19. Linardic CM and Hannun YA. Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle. J Biol Chem 269: 23530-23537, 1994.
20. Mathias S, Dressler KA, and Kolesnick RN. Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor a. Proc Natl Acad Sci USA 88: 10009-10013, 1991.
21. Mathias S and Kolesnick R. Ceramide: a novel second messenger. Adv Lipid Res 25: 65-90, 1993.
22. Missiacn L, Smedt HD, Droogmans G, Himpens B, and Casteels R. Calcium ion homeostasis in smooth muscle. Pharmacol Ther 56: 191-231, 1992.
23. 2+ modulates membrane sphingolipid and lipid second messenger levels in vascular smooth muscle cells. FEBS Lett 440: 167-171, 1998.
24. Raines MA, Kolesnick RN, and Golde DW. Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells. J Biol Chem 268: 14572-14575, 1993.
25. Riboni L, Viani P, Bassi R, Prinetti A, and Tettamanti G. The role of sphingolipids in the process of signal transduction. Prog Lipid Res 36: 153-195, 1997.
26. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801-809, 1993.
27. Rüegg VT and Burgen GM. Staurosporine, K-252 and VCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol Sci 10: 218-220, 1989.
28. Sbrissa D, Yamada H, Hajra A, and Bitar KN. Bombesin-stimulated ceramide production and MAP kinase activation in rabbit rectosigmoid smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 272: G1615-G1625, 1997.
29. Schissel SL, Tweedie-Hardman J, Rapp JH, Graham G, Williams KJ, and Tabas I. Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins. J Clin Invest 98: 1455-1464, 1996.
30. Schwartz SM, Heimark RL, and Majesky MW. Developmental mechanisms underlying pathology of arteries. Physiol Rev 70: 1177-1209, 1990.
31. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, and Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 24: 15771-15781, 1991.
32. Wiegmann K, Schütze S, Machleidt T, Witte D, and Krönke M. Functional dichotomy of neutral and acidic sphingomyelinase in tumor necrosis factor signaling. Cell 78: 1005-1015, 1994.
33. +. Br J Pharmacol 105: 305-310, 1992.
34. Zhang A, Altura BT, and Altura BM. Ethanol-induced contraction of cerebral arteries in diverse mammals and its mechanism of action. Eur J Pharmacol 248: 229-236, 1993.
35. Zhang A, Cheng TPO, and Altura BM. Ethanol decreases cytosolic-free calcium ions in vascular smooth muscle cells as assessed by digital image analysis. Alcohol Clin Exp Res 16: 55-57, 1992.
36. Zhang A, Cheng TPO, and Altura BM. Magnesium regulates intracellular free ionized calcium concentration and cell geometry in vascular smooth muscle cells. Biochim Biophys Acta 1134: 25-29, 1992.
37. i: relation to etiology of alcohol-induced stroke. Alcohol 14: 367-371, 1997.
38. 2+ in EDRF release in rat aorta. J Vasc Res 31: 18-24, 1994.
39. i in canine cerebral vascular smooth muscle. Neurosci Lett 256: 113-116, 1998.
40. i in rat aortic smooth muscle. Lipids 34: 689-695, 1999.
41. 2+ mobilization in rat aortic smooth muscle. Eur J Pharmacol. In press.