Gene therapy for intraperitoneally disseminated pancreatic cancers by Escherichia coli uracil phosphoribosiltransferase (UPRT) gene mediated by restricted replication-competent adenoviral vectors

International Journal of Cancer

Volumn 102, Issue 1, 2002, Pages 51-59

  Oonuma, Masaru ^a   Sunamura, Makoto ^a,c   Motoi, Fuyuhiko ^a   Fukuyama, Shouji ^a   Shimamura, Hiromune ^a   Yamauchi, Jun Ichiro ^a   Shibuya, Kazuhiko ^a   Egawa, Shin Ichi ^a   Hamada, Hirofumi ^b   Takeda, Kazunori ^a   Matsuno, Seiki ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Gene therapy; Pancreatic cancer; Peritoneal dissemination; Replicating adenovirus; UPRT

Indexed keywords

ADENOVIRUS VECTOR; FLOXURIDINE PHOSPHATE; FLUOROURACIL; PROTEIN; PROTEIN AXEIADB; UNCLASSIFIED DRUG; URACIL PHOSPHORIBOSYLTRANSFERASE;

ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MALE; METASTASIS; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; REPORTER GENE; TOXICITY; VIRUS REPLICATION; XENOTRANSPLANTATION;

ADENOVIRIDAE; ADENOVIRUS E1B PROTEINS; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BETA-GALACTOSIDASE; CELL DIVISION; ESCHERICHIA COLI; FLUORODEOXYURIDYLATE; FLUOROURACIL; GENE THERAPY; GENETIC VECTORS; HUMANS; IMMUNOENZYME TECHNIQUES; INJECTIONS, INTRAPERITONEAL; LAC OPERON; MALE; MICE; MICE, SCID; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PENTOSYLTRANSFERASES; RECOMBINATION, GENETIC; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; VIRUS REPLICATION;

EID: 0036837479     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10650     Document Type: Article

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