Role of protein kinase C α in primary human osteoblast proliferation

Journal of Bone and Mineral Research

Volumn 17, Issue 11, 2002, Pages 1968-1976

  Lampasso, J D ^a   Marzec, N ^b   Margarone, J ^c   Dziak, R ^c  

^a UNIVERSITY AT BUFFALO   (United States)

^b Williamsville NY   (United States)

^c NONE   (United States)

Author keywords

Isoforms; Oligodeoxynucleotides; Osteoblast; Proliferation; Protein kinase C

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OSSIFICATION; OSTEOBLAST; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

CELL COMPARTMENTATION; CELL DIVISION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; HUMANS; ISOENZYMES; LYSOPHOSPHOLIPIDS; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASES; MITOGENS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OSTEOBLASTS; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-DELTA; PROTEIN TRANSPORT; SPHINGOSINE;

EID: 0036828407     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2002.17.11.1968     Document Type: Article

References (33)

1. Nishizuka Y 1984 Turnover of inositol phospholipids and signal transduction. Science 225:1365-1370.
2. Mathews SA, Rozengurt E, Cantrell D 2000 Protein kinase D. A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes. J Exp Med 191:2075-2082.
3. Rosales OR, Isales CM, Bhargava J 1998 Overexpression of protein kinase C α and β1 has distinct effects on bovine aortic endothelial cell growth. Cell Signal 10:589-597.
4. Parames S, Vijaya K, Sen S 1998 Increased protein kinase C activity in myotrophin induced myocyte growth. Circ Res 82:1173-1188.
5. Capiati D, Tellez-Inon MT, Boland RL 1999 Participation of protein kinase C alpha in 1,25 dihydroxy-vitamin D3 regulation of chick myoloblast proliferation and differentiation. Mol Cell Endocrinol 153:39-45.
6. Busuttil SJ, Morehouse MD, Yourkey MD, Singer HA 1996 Antisense suppression of protein kinase C-α and -δ in vascular smooth muscle. J Surg Res 63:137-142.
7. Carpio LC, Stephan E, Kamer A, Dziak R 1999 Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells. Prostaglandins Leukot Essent Fatty Acids 61:267-273.
8. Oliver A, Spiegel S 1993 Sphingosine 1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 138:220-229.
9. Rani CS, Wang F, Fuior E, Berger A, Wu J, Sturgill TW, Beitner-Johnson D, LeRoith D, Varticovski L, Spiegel S 1997 Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. J Biol Chem 272:10777-10783.
10. Sato K, Ishikawa K, Ui M, Okajima F 1999 Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells. Mol Brain Res 74:182-189.
11. Banno Y, Fujita H, Ona Y, Nakashima S, Ito Y, Kuzumaki N, Nozawa Y 1999 Differential phospholipase D activation by bradykinin and sphingosine 1-phosphate in NIH 3T3 fibroblasts overexpressing gelsolin. J Biol Chem 274:27385-27391.
12. Lampasso JD, Kamer A, Margarone J III, Dziak R 2001 Sphingosine-1-phosphate effects on PKC isoform expression in human osteoblastic cells. Prostaglandins Leukot Essent Fatty Acids 65:139-146.
13. Chen CC, Wang JK, Lin SB 1998 Antisense oligonucleotides targeting protein kinase C-α, -β1, or -δ but not -η inhibit lipopolysacharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: Involvement of a nuclear factor kB-dependent mechanism. J Immunol 161:6206-6214.
14. Liedtke CM, Cole T 1997 Antisense oligonucleotide to PKC δ blocks α1-adrenergic activation of Na-K-2Cl co-transport. Am J Physiol 273:C1632-C1640.
15. Dominguez I, Diaz-Meco MT, Municio MM, Berra E, Garcia DE, Herreros A, Cornet ME, Sanz L, Muscat J 1992 Evidence for a role of protein kinase C ζ subspecies in maturation of Xenopus laevis Oocytes. Mol Cell Biol 12:3776-3783.
16. Racke FK, Wang D, Zaidi Z, Kelley J, Visvader J, Soh JW, Goldfarb AN 2001 A potential role for protein kinase C-ε in regulating megakaryocytic lineage commitment. J Biol Chem 276:522-528.
17. Wooten MW, Seibenhener ML, Zhou G, Vandenplas ML, Tan TH 1999 Overexpression of atypical PKC in PC12 cells enhances NGF-responsiveness and survival through an NF-kappaB dependent pathway. Cell Death Differ 6:753-764.
18. Pardee AB 1989 G1 events and regulation of cell proliferation. Science 246:603-608 (review).
19. Moreton K, Turner R, Blake N, Paton A, Groome N, Rumsby M 1995 Protein expression of the α, γ,δ and ε subspecies of protein kinase C changes as C6 glioma cells become contact inhibited and quiescent in the presence of serum. FEBS Lett 372:33-38.
20. Yuen AR, Halsey J, Fisher GA, Holmlund JT, Geary RS, Kwoh TJ, Dorr A, Sikic BI 1999 Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer. Clini Cancer Res 5:3357-3363.
21. Nemunaitis J, Holmlund JT, Kraynak M, Richards D, Bruce J, Ognoskie N, Kwoh TJ, Geary R, Dorr A, Von Hoff D, Eckhardt SG 1999 Phase I evaluation of ISIS 3521, an antisense oligonucleotide to protein kinase C-alpha, in patients with advanced cancer. J Clin Oncol 17:3586-3595.
22. Murray NR, Fields AP 1997 A typical protein kinase Cι protects human leukemia cells against drug-induced apoptosis. J Biol Chem 272:27521-27524.
23. Bulteau L, Raymond G, Cognard C 1998 Antisense oligonucleotides against 'cardiac' and 'skeletal' DHP-receptors reveal a dual role for the 'skeletal' isoform in EC coupling of skeletal muscle cells in primary culture. J Cell Sci 111:2149-58.
24. Zhang X, Wen J, Aletta JM, Rubin RP 1997 Inhibition of expression of PKC α by antisense mRNA is associated with diminished cell growth and inhibition of amylase secretion by AR4-2J cells. Exp Cell Res 233:225-231.
25. Chaudry LR, Avioli LV 1997 Activation of extracellular signal-regulated kinases 1 and 2 (ERK1 & ERK2) by FGF-2 and PDGF-BB in normal human osteoblastic and bone marrow stromal cells: Differences in mobility and in-gel renaturation of ERK1 in humans, rat and mouse osteoblastic cells. Biochem Biophys Res Commun 238:134-139.
26. Mani I, Iversen L, Ziboh WA 1998 Up regulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: Modulation by 13M-(S)-hydroxyoctadecadienoic acid. Cell Signal 10:143-149.
27. Goodnight J, Mischak H, Kolch W, Mushinski F 1995 Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH-3T3 fibroblasts. J Biol Chem 270:9991-10001.
28. Neri LM, Billi AM, Manzoli L, Rubbini S, Gilmour RS, Cocco L, Martelli AM 1994 Selective nuclear translocation of PKC α in Swiss 3T3 cells treated with IGF-I PDGF and EGF. FEBS Lett 347:63-68.
29. Haller H, Quass P, Lindschau C, Luft FC, Dister A 1994 Platelet derived growth factor and angiotensin II induce different spatial distribution of PKC α and β in vascular smooth muscle cells. Hypertension 23:848-852.
30. Zini N, Martelli AM, Neri LM, Bavelloni A, Sabatelli P, Santi S, Maraldi NM 1995 Immunocytochemical evaluation of PKC translocation to the inner nuclear matrix in 3T3 mouse fibroblast after IGF-I treatment. Histochemistry 102:447-457.
31. Sanders J, Stern P 1996 Expression and phorbol ester-induced down-regulation of protein kinase C isozymes in osteoblasts. J Bone Miner Res 11:1862-1872.
32. Sakai T, Okano Y, Nozawa Y, Oka N 1992 Different protein kinase C isozymes could modulate bradykinin-induced extracellular calcium dependent and -independent increases in osteoblast-like MC3T3-E1 cells. Cell Calcium 13:329-340.
33. Lampasso JD, Intini G, Dziak R 2000 Effects of 1,25 dihydroxyvitamin D3 on PKC isoform expression. Int J Oral Biol 25:65-73.