Increased protein kinase C activity in myotrophin-induced myocyte growth

Circulation Research

Volumn 82, Issue 11, 1998, Pages 1173-1188

  Sil, Parames ^a   Kandaswamy, Vijaya ^a   Sen, Subha ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Hypertrophy; Myocytes; Myotrophin; PKC; myosin heavy chain

Indexed keywords

MYOSIN HEAVY CHAIN; PROTEIN KINASE C; RECOMBINANT SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; CELL GROWTH; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; HORMONE RESPONSE; MOLECULAR CLONING; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SYNTHESIS INHIBITION; RAT; SIGNAL TRANSDUCTION;

EID: 0032526919     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.82.11.1173     Document Type: Article

References (60)

1. Kannel WB, Dawber TR, Kagan A, Revotskie N. Suzuki K. Factors of risk in the development of coronary heart disease: six years' follow-up experience. Ann Intern Med. 1961;55:33-50.
2. Kannel WB, Gordon T, Castelli WP, Margolis JR. Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease: the Framingham study. Ann Intern Med. 1970;72:813-822.
3. 1-adrenoceptor mediated phosphoinositide breakdown in cardiomyocytes. J Mol Cell Cardiol. 1989;21:661-668.
4. Dunnmon PM, Iwaki K, Henderson SA, Sen A, Chien KR. Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells. J Mol Cell Cardiol. 1990;22:901-910.
5. Chien KR, Knowlton KU, Zhu H, Chien S. Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J. 1991;5:3037-3046.
6. Nishizuka Y. The molecular heterogeneity of protein kinase C and its implication for cellular regulation. Nature. 1988;334:661-665.
7. Coussens L, Parker PJ, Rhee L, Yang-Feng TL, Chen E, Waterfield MD. Francke U, Ullrich A. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science. 1986;233:859-866.
8. Henrich CJ, Simpson PC. Differential acute and chronic response of protein kinase C in cultured neonatal rat heart myocytes to α1-adrenergic and phorbol ester stimulation. J Mol Cell Cardiol. 1988;20:1081-1085.
9. Sen S, Tarazi RC, Bumpus FM. Cardiac hypertrophy and antihypertensive therapy. Cardiovasc Res. 1977;11:427-433.
10. Sen S, Tarazi RC, Khairallah PA, Bumpus FM. Cardiac hypertrophy in spontaneously hypertensive rats. Circ Res. 1974;35:775-781.
11. Sen S, Tarazi RC. Regression of myocardial hypertrophy and influence of adrenergic system. Am J Physiol. 1983;244;H97-H101.
12. Freis E. Essential hypertension and spontaneous hypertension. In: Okamoto K, ed. Pathogenesis of Hypertension. Tokyo, Japan: Igaku, Shoin; 1972:231-244.
13. Hollander W, Madoff I, Paddock J, Kirkpatrick B. Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta. Circ Res. 1976;38:63-72.
14. Tomanek RJ, Davis JW, Anderson SC. The effects of α-methyldopa on cardiac hypertrophy in spontaneously hypertensive rats: ultrastructural, stereological, and morphometric analysis. Cardiovasc Res. 1979;13: 173-182.
15. Yamori Y, Mori C, Nishio T, Ooshima A, Horie R, Ohtaka M, Soeda T, Saito M, Abe K, Nara Y, Nakao Y, Kihara M. Cardiac hypertrophy in early hypertension. Am J Cardiol. 1979;44:964-969.
16. Sen S, Factors regulating myocardial hypertrophy in hypertension. Circulation. 1987;75:181-184.
17. Sen S, Petscher C, Ratliff N. A factor that initiates myocardial hypertrophy in hypertension. Hypertension. 1987;9:261-267.
18. Sen S, Kundu G, Mekhail N, Castel J, Misono K, Healy B. Myotrophin: purification of a novel peptide from spontaneously hypertensive rat heart that influences myocardial growth. J Biol Chem. 1990;265:16635-16643.
19. Sil P, Sen S. Purification of myotrophin from human cardiomyopathic heart. FASEB J. 1991;5:A1244. Abstract.
20. Sil P, Misono K, Sen S. Myotrophin in human cardiomyopathic heart. Circ Res. 1993;73:98-108.
21. Mukherjee D, McTiernan CF, Sen S. Effect of myotrophin on induction of proto-oncogenes ANF and contractile element transcript levels. Circulation. 1992;86(suppl I):I-626. Abstract.
22. Sivasubramanian N, Adhikary G, Sil PC, Sen S. Cardiac myotrophin exhibits rel/NK-kB interacting activity in vitro. J Biol Chem. 1996;271: 2812-2816.
23. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 1992;258:607-614.
24. Kohout TA, Rogers TB. Use of a PCR-based method to characterize protein kinase C isoform expression in cardiac cells. Am J Physiol. 1993;264:C1350-C1359.
25. Pears CJ, Parker PJ. Domain interactions in protein kinase C. J Cell Sci. 1991;100:683-686.
26. Stabel S, Parker PI. Protein kinase C. Pharmacol Ther. 1991;51:71-95.
27. Clemens MJ, Trayner I, Menaya J. The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation. J Cell Sci. 1992;103:881-887.
28. Azzi A, Boscoboinik D, Hensey C. The protein kinase C family. Eur J Biochem. 1992;208:547-557.
29. Hug H, Sarre TF. Protein kinase C isoenzymes: divergence in signal transduction? Biochem J. 1993;291:329-343.
30. Ono Y, Fujii T, Ogita K, Kikkawa U, Igarashi K, Nishizuka Y. Protein kinase C ζ subspecies from rat brain: its structure, expression, and properties. Proc Natl Acad Sci U S A. 1989;86:3099-3103.
31. Selbie LA, Schmitz-Peiffer C, Sheng Y, Biden TJ. Molecular cloning and characterization of PKCι, an atypical isoform of protein kinase C derived from insulin-secreting cells. J Biol Chem. 1993;268:24296-24302.
32. Akimoto K, Mizuno K, Osada S, Hirai S, Tanuma S, Suzuki K, Ohno S. A new member of the third class in the protein kinase C family, PKCλ. expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells. J Biol Chem. 1994;269:12677-12683.
33. Rybin VO, Steinberg SF. Protein kinase C isoform expression and regulation in the developing rat heart. Circ Res. 1994;74:299-309.
34. Shearman MS, Ogita K, Kikkawa U, Nishizuka Y. A rapid method for the resolution of protein kinase C subspecies from rat brain tissue. Methods Enzymol. 1989;168:347-351.
35. Rybin V, Steinberg SF. Thyroid hormone represses protein kinase C isoform expression and activity in rat cardiac myocytes. Circ Res. 1996; 79:388-398.
36. Kitano T, Go M, Kikkawa U, Nishizuka Y. Assay and purification of protein kinase C. Methods Enzymol. 1986;124:349-352.
37. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
38. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
39. Towbin HT, Stachelin T, Gordon J. Electrophoretic transfers of proteins from polyacrylamide gels to nitrocellulose sheets. Proc Natl Acad Sci U S A. 1979;79:4350-4354.
40. Tsang VCW, Peralta JM, Simons AR. Enzyme-linked immuno-electrotransfer blot techniques (EITB) for studying the specificities of antigens and antibodies separated by gel electrophoresis. Methods Enzymol. 1983;92:377-391.
41. Baxter GT, Miller DL, Kuo RC, Wada HG, Owicki JC. PKCε is involved in granulocyte-macrophage colony-stimulating factor signal transduction: evidence from microphysiometry and antisense oligonucleotide experiments. Biochemistry. 1992;31:10950-10954.
42. Steinberg SF, Goldberg M, Rybin VO. Protein kinase C isoform diversity in the heart. J Mol Cell Cardiol. 1995;27:141-153.
43. Paul K. Ball NA, Dom GW II, Walsh RA. Left ventricular stretch stimulates angiotensin II-mediated phosphatidylinositol hydrolysis and protein kinase Cε isoform translocation in adult guinea pig hearts. Circ Res. 1997;81:643-650.
44. Nishizuka Y. Turnover of inositol phospholipids and signal transduction. Science. 1984;225:1365-1370.
45. Rozengurt E. Early signals in the mitogenic response. Science. 1986;234: 161-166.
46. Richter EA, Cleland PJ, Rattigan S, Clark MG. Contraction-associated translocation of protein kinase C in rat skeletal muscle. FEBS Lett. 1987;217:232-236.
47. Morgan HE, Gordon EE, Kira Y, Chua HL, Russo LA, Peterson CJ, McDermott PJ, Watson PA. Biochemical mechanisms of cardiac hypertrophy. Annu Rev Physiol. 1987;49:533-543.
48. Lehoux JG, Grondin F, Pacuraru JP, Yachaoui Y. The protein kinase C content is increased in the nuclear fraction of rat adrenal zona glomerulosa following long-term ACTH administration. Mol Cell Endocrinol. 1991;78:97-106.
49. Allo SN, McDermott PJ, Carl LL, Morgan HE. Phorbol ester stimulation of protein kinase C activity and ribosomal DNA transcription: role in hypertrophic growth of cultured cardiomyocytes. J Biol Chem. 1991;266: 22003-22009.
50. Gu X, Bishop SP. Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat. Circ Res. 1994;75: 926-931.
51. Johnson JA, Mochly-Rosen D. Inhibition of the spontaneous rate of contraction on neonatal cardiac myocytes by protein kinase C isozymes: a putative role for the c isozyme. Circ Res. 1995;76:654-663.
52. Shubeita HE, Martinson EA. Van Bilsen M, Chien KR, Brown JH. Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes. Proc Natl Acad Sci U S A. 1992;89:1305-1309.
53. Kariya K, Karns LR, Simpson PC. Expression of a constitutively activated mutant of the β-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the β-myosin heavy chain isogene. J Biol Chem. 1991;266:10023-10026.
54. Izumo S, Lompre AM, Matsuoka R, Koren G, Schwartz K, Nadal-Ginard B, Mahdavi V. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy: interaction between hemodynamic and thyroid hormone-induced signals. J Clin Invest. 1987;79:970-977.
55. Schwartz K, de la Bastie D, Bouveret P, Oliviero P, Alonso S, Buckingham M. α-Skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts. Circ Res. 1986;59:551-555.
56. Izumo S, Nadal-Ginard B, Mahdavi V. Proto-oncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci U S A. 1988;85:339-343.
57. Schaap D, Parker PJ. Expression, purification, and characterization of protein kinase C-ε. J Biol Chem. 1990;265:7301-7307.
58. Bazzi MD, Nelsestuen GL. Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation. Biochemistry. 1987;26:1974-1982.
59. Xu Y, Yau L, Yu L, Elimban V, Zahradka P, Dhalla NS. Stimulation of protein synthesis by phosphatidic acid in rat cardiomyocytes. Biochem Pharmacol. 1996;52:1735-1740.
60. Na via multiple protein kinase pathways. Circ Res. 1997;81:387-395.