Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss

Journal of Neurosurgery

Volumn 92, Issue 6, 2000, Pages 983-990

  Ino, Yasushi ^b   Zlatescu, Magdalena C ^b   Sasaki, Hikaru ^b   Macdonald, David R ^b   Stemmer Rachamimov, Anat O ^b   Jhung, Sarah ^b   Ramsay, David A ^b   Von Deimling, Andreas ^b   Louis, David N ^a   Cairncross, J Gregory ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

Chromosome marker; Glioblastoma multiforme; Oligodendroglioma

Indexed keywords

ADULT; ANAPLASTIC CARCINOMA; ARTICLE; ASTROCYTOMA; CANCER GRADING; CANCER SURVIVAL; CHROMOSOME 1P; CHROMOSOME LOSS; CHROMOSOME MARKER; CLINICAL ARTICLE; FEMALE; GLIOBLASTOMA; GLIOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; OLIGODENDROGLIOMA; PHENOTYPE; PRIORITY JOURNAL;

EID: 0034036250     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2000.92.6.0983     Document Type: Article

References (20)

1. Bello MJ, Leone PE, Nebreda P, et al: Allelic status of chromosome 1 in neoplasms of the nervous system. Cancer Genet Cytogenet 83:160-164, 1995
2. Burger PC, Scheithauer BW: Tumors of the Central Nervous System. Atlas of Tumor Pathology, Ser 3, Fasc 10. Washington, DC: Armed Forces Institute of Pathology, 1994
3. Cairncross JG, Ueki K, Zlatescu MC. et al: Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 90: 1473-1479, 1998
4. Hayashi Y, Ueki K, Waha A, et al: Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathol 7:871-875, 1997
5. Hermanson M, Funa K, Koopmann J, et al: Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor a receptor expression in human malignant gliomas. Cancer Res 56:164-171, 1996
6. Kleihues P, Burger PC, Scheithauer BW: Histological Typing of Tumours of the Central Nervous System. Berlin: Springer-Verlag, 1993
7. Kraus JA, Koopmann J, Kaskel P, et al: Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 54:91-95, 1995
8. Levin VA, Edwards MS, Wright DC, et al: Modified procarbazine, CCNU, and vincristine (PCV 3) combination chemotherapy in the treatment of malignant brain tumors. Cancer Treat Rep 64:237-244, 1980
9. Louis DN: Clinicopatho-genetic subsets of glioblastoma multiforme: from both sides now. Brain Pathol 6:223-224, 1996
10. Louis DN, Cavenee WK: Molecular biology of central nervous system neoplasms, in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology, ed 5. Philadephia: Lippincott-Raven, 1997, pp 2013-2022
11. Louis DN, Gusella JF: A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet 11: 412-415, 1995
12. Louis DN, Rubio MP, Correa KM, et al: Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens. J Neuropathol Exp Neurol 52:507-515, 1993
13. Louis DN, von Deimling A, Chung RY, et al: Comparative study of p53 gene and protein alterations in human astrocytic tumors. J Neuropathol Exp Neurol 52:31-38, 1993
14. n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens. Am J Pathol 141:777-782, 1992
15. Maintz D, Fiedler K, Koopmann J, et al: Molecular genetic evidence for subtypes of oligoastrocytomas. J Neuropathol Exp Neurol 56:1098-1104, 1997
16. Ono Y, Tamiya T, Ichikawa T, et al: Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices. J Neuropathol Exp Neurol 55: 1026-1031, 1996
17. Rubio MP, von Deimling A, Yandell DW, et al: Accumulation of wild type p53 protein in human astrocytomas. Cancer Res 53:3465-3467, 1993
18. Ueki K, Ono Y, Henson JW, et al: CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 56:150-153, 1996
19. von Deimling A, Louis DN, von Ammon K, et al: Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. J Neurosurg 77:295-301, 1992
20. von Deimling A, von Ammon K, Schoenfeld D, et al: Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol 3:19-26, 1993