Up-regulation of the TrkB receptor in mice injured by the partial ligation of the sciatic nerve

European Journal of Pharmacology

Volumn 401, Issue 2, 2000, Pages 187-190

  Narita, Minoru ^a   Yajima, Yoshinori ^a   Aoki, Takeshi ^a   Ozaki, Satoru ^a   Narita, Michiko ^b   Mizoguchi, Hirokazu ^b   Tseng, Leon F ^b   Suzuki, Tsutomu ^a  

^a HOSHI UNIVERSITY   (Japan)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Chronic pain; Mouse; Nerve ligation; Protein kinase C; Spinal cord; TrkB receptor

Indexed keywords

PROTEIN KINASE C; TYROSINE KINASE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; HYPERALGESIA; MALE; MOUSE; NERVE LIGATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SCIATIC NERVE; SPINAL CORD; SYNAPTIC TRANSMISSION;

ANIMALS; HYPERALGESIA; ISOENZYMES; LIGATION; MALE; MICE; MICE, INBRED ICR; PROTEIN KINASE C; RECEPTOR, TRKB; SCIATIC NERVE; SPINAL CORD; UP-REGULATION;

EID: 0034604799     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00449-0     Document Type: Article

References (14)

1. Coderre T.J. Contribution of protein kinase C to central sensitization and persistent pain following tissue injury. Neurosci. Lett. 140:1992;181-184.
2. Kaplan D.R., Stephens R.M. Neurotrophin signal transduction by the Trk receptor. J. Neurobiol. 25:1994;1404-1417.
3. Lewin G.R, Mendell L.M. Nerve growth factor and nociception. Trends Neurosci. 16:1993;353-359.
4. Malmberg A.B., Chen C., Tonegawa S., Basbaum A.I. Preserved acute pain and reduced neuropathic pain in mice lacking PKCγ Science. 278:1997;279-283.
5. Maness L.M., Kastin A.J., Weber J.T., Banks W.A., Beckman B.S., Zadina J.E. The neurotrophines and their receptors: structure, function, and neuropathology. Neuro Biobehav. Res. 18:1994;143-159.
6. Mao J., Mayer D.J., Hayes R.L., Price D.D. Spatial patterns of increased spinal cord membrane-bound protein kinase C and their relation to increases in 14C-2-deoxyglucose metabolic activity in rats with painful peripheral mononeuropathy. J. Neurophysiol. 70:1993;470-481.
7. Meller S.T., Dykstra C., Gebhart G.F. Acute thermal hyperalgesia in the rat is produced by activation of N-methyl-D-aspartate receptors and protein kinase C and production of nitric oxide. Neuroscience. 71:1996;327-335.
8. Seltzer Z., Dubner R., Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 43:1990;205-218.
9. Stephens R.M., Loeb D.M., Copeland T.D., Pawson T., Greene L.A., Kaplan D.R. Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ1 to mediate NGF responses. Neuron. 12:1994;691-705.
10. Theodosiou M., Rush R.A., Zhou X.F., Hu D., Walker J.S., Tracey D.J. Hyperalgesia due to nerve damage: role of nerve growth factor. Pain. 81:1999;245-255.
11. Thoenen H. The changing scene of neurotrophic factors. Trends Neurosci. 14:1991;165-170.
12. Thompson S.W.N., Bennett D.L.H., Kerr B.J., Bradbury E.J., McMahon S.B. Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord. Proc. Natl. Acad. Sci. U. S. A. 96:1999;7714-7718.
13. Woolf C.J., Costigan M. Transcriptional and post-translational plasticity and the generation of inflammatory pain. Proc. Natl. Acad. Sci. U. S. A. 96:1999;7723-7730.
14. Zhou X.F., Rush R.A. Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons. Neuroscience. 74:1996;945-951.