Reveromycin A inhibits antigen receptor-mediated antigen presentation by B lymphoma cells via its effect on intracellular trafficking of the antigen

Journal of Antibiotics

Volumn 55, Issue 10, 2002, Pages 904-913

  Tanaka, Yuriko ^a   Ishikawa, Fumio ^a   Osada, Hiroyuki ^a   Imajoh Ohmi, Shinobu ^a   Uchida, Tetsuya ^a   Kakiuchi, Terutaka ^a  

^a TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; B LYMPHOCYTE RECEPTOR; BAFILOMYCIN A1; BREFELDIN A; CYCLOHEXIMIDE; EMETINE; EPIDERMAL GROWTH FACTOR; GENISTEIN; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; OVALBUMIN; PEPTIDE DERIVATIVE; PROTEIN TYROSINE KINASE INHIBITOR; REVEROMYCIN A; STAUROSPORINE; TRINITROPHENYL; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANIMAL CELL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; B CELL LYMPHOMA; CELL GROWTH; CELL SPECIFICITY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG MECHANISM; ENDOCYTOSIS; ENDOSOME; INCUBATION TIME; INTERNALIZATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; STRAIN DIFFERENCE; T LYMPHOCYTE;

EID: 0036808676     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.55.904     Document Type: Article

References (41)

1. CHESNUT, R. W. & H. M. GREY: Antigen presentation by B cells and its significance in T-B interactions. Adv. Immunol. 39: 51-94, 1986
2. LANZAVECCHIA, A.: Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. Annu. Rev. Immunol. 8: 773-793, 1990
3. TOWNSEND, S. E. & C. C. GOODNOW: Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo. J. Exp. Med. 187: 1611-1621, 1998
4. CONSTANT, S. L.: B lymphocytes as antigen-presenting cells for CD4+ T cell priming in vivo. J. Immunol. 162: 5695-5703, 1999
5. VAN LITH, M.; M. VAN HAM, A. GRIEKSPOOR, E. TJIN, D. VERWOERD, J. CALAFAT, H. JANSSEN, E. REITS, L. PASTOORS & J. NEEFJES: Regulation of MHC class II antigen presentation by sorting of recycling HLA-DM/DO and class II within the multivesicular body. J. Immunol. 167: 884-892, 2001
6. BATISTA, F. D.; D. IBER & M. S. NEUBERGER: B cells acquire antigen from target cells after synapse formation. Nature 411: 489-494, 2001
7. TARLINTON, D.: Antigen presentation by memory B cells: the sting is the tail. Science 276: 374-375, 1997
8. CHESNUT, R. W. & H. M. GREY: Studies on the capacity of B cells to serve as antigen-presenting cells. J. Immunol. 126: 1075-1079, 1981
9. LANZAVECCHIA, A.: Antigen-specific interaction between T and B cells. Nature 314: 537-539, 1985
10. QIU Y.; X. XU, A. WANDINGER-NESS, D. P. DALKE & S. K. PIERCE: Separation of subcellular compartments containing distinct functional forms of MHC class II. J. Cell Biol. 125: 595-605, 1994
11. DRAKE, J. R.; T. A. LEWIS, K. B. CONDON, R. N. MITCHELL & P. WEBSTER: Involvement of MIIC-like late endosomes in B cell receptor-mediated antigen processing in murine B cells. J. Immunol. 162: 1150-1155, 1999
12. DRAKE, J. R.; P. WEBSTER, J. C. CAMBIER & I. MELLMAN: Delivery of B cell receptor-internalized antigen to endosomes and class II vesicles. J. Exp. Med. 186: 1299-1306, 1997
13. SONG, W.; H. CHO, P. CHENG & S. K. PIERCE: Entry of B cell antigen receptor and antigen into class II peptide-loading compartment is independent of receptor cross-linking. J. Immunol. 155: 4255-4263, 1995
14. ALUVIHARE, V. R.; A. A. KHAMLICHI, G. T. WILLIAMS, L. ADORINI & M. S. NEUBERGER: Acceleration of intracellular targeting of antigen by the B-cell antigen receptor: importance depends on the nature of the antigen-antibody interaction. EMBO J. 16: 3553-3362, 1997
15. SIEMASKO, K.; B. J. EISFELDER, C. STEBBINS, S. KABAK, A. J. SANT, W. SONG & M. R. CLARK: Ig alpha and Ig beta are required for efficient trafficking to late endosomes and to enhance antigen presentation. J. Immunol. 162: 6518-6525, 1999
16. BROWN, B. K.; C. LI, P. C. CHENG & W. SONG: Trafficking of the Ig alpha/Ig beta heterodimer with membrane Ig and bound antigen to the major histocompatibility complex class II peptide-loading compartment. J. Biol. Chem. 274: 11439-11446, 1999
17. CHENG, P. C.; C. R. STEELE, L. Gu, W. SONG & S. K. PIERCE: MHC class II antigen processing in B cells: accelerated intracellular targeting of antigens. J. Immunol. 62: 7171-7180, 1999
18. GONDRE-LEWIS, T. A.; A. E. MOQUIN & J. R. DRAKE: Prolonged antigen persistence within nonterminal late endocytic compartments of antigen-specific B lymphocytes. J. Immunol. 166: 6657-6664, 2001
19. KAKIUCHI, T.; M. WATANABE, N. HOZUMI & H. NARIUCHI: Differential sensitivity of specific and nonspecific antigen-presentation by B cells to a protein synthesis inhibitor. J. Immunol. 145: 1653-1658, 1990
20. KAKIUCHI, T.; A. TAKATSUKI, M. WATANABE & H. NARIUCHI: Inhibition by brefeldin A of the specific B cell antigen presentation to MHC class II-restricted T cells. J. Immunol. 147: 3289-3295, 1991
21. GRIFFIN, J. P.; R. CHU & C. V. HARDING: Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms. J. Immunol. 158: 1523-1532, 1997
22. BRIKEN, V.; D. LANKAR & C. BONNEROT: New evidence for two MHC class II-restricted antigen presentation pathways by overexpression of a small G protein. J. Immunol. 159: 4653-4658, 1997
23. PINET, V. M. & E. O. LONG: Peptide loading onto recycling HLA-DR molecules occurs in early endosomes. Eur. J. Immunol. 28: 799-804, 1998
24. FORQUET, F.; N. BAROIS, P. MACHY, J. TRUCY, V. S. ZIMMERMANN, L. LESERMAN & J. DAVOUST: Presentation of antigens internalized through the B cell receptor requires newly synthesized MHC class II molecules. J. Immunol. 162: 3408-3416, 1999
25. SIEMASKO, K.; B. J. EISFELDER, E. WILLIAMSON, S. KABAK & M.R. CLARK: Cutting edge: signals from the B lymphocyte antigen receptor regulate MHC class II containing late endosomes. J. Immunol. 160: 5203-5208, 1998
26. OSADA, H.; H. KOSHINO, H. TAKAHASHI, G. KAWANISHI & K. ISONO: Reveromycin A, a new antibiotic which inhibits the mitogenic activity of epidermal growth factor. J. Antibiotics 44: 259-261, 1991
27. TAKAHASHI, H.; Y. YAMASHITA, H. TAKAOKA, J. NAKAMURA, M. YOSHIHAMA & H. OSADA: Inhibitory action of reveromycin A on TGF-α-dependent growth of ovarian carcinoma BG-1 in vitro and in vivo. Oncol. Res. 9: 7-11, 1997
28. EISEN, H. N.: Preparation of immunologenic 2,4-dinitrophenil proteins. In Methods in immunology and immunocytochemistry, Vol. 1. Ed., C. A. WILLIAMS et al., pp. 128-133, Academic Press, New York. 1967
29. BHATTACHARYA, A.; M. E. DORF & T. A. SPRINGER: A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J. Immunol. 127: 2488-2495, 1981
30. DIALYNAS, D. P.; Z. S. QUAN, K. A. WALL, A. PIERRES, J. QUINTANS, M. R. LOKEN, M. PIRRES & F. W. FITCH: Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human leu-3/T4 molecule. J. Immunol. 131: 2445-2451, 1983
31. HOLMES, K. & B. J. FOWLKES: Preparation of cells and reagents for flow cytometry. In Current protocols in immunology. Ed., J. E. COLIGAN et al., pp. 5.3.5-5.3.6, Wiley, New York. 1995
32. WATANABE, M.; D. R. WEGMANN, A. OCHI & N. HOZUMI: Antigen presentation by a B-cell line transfected with cloned immunoglobulin heavy- and light-chain genes specific for a defined hapten. Proc. Natl. Acad. Sci. USA. 83: 5247-5251, 1986
33. AOI, T.; H. NAKANO, Y. TANAKA & T. KAKIUCHI: Enhancement of antigen-presenting ability of B lymphoma cells by partial inhibition of protein synthesis through inducing B7-1 expression. Immunology. 91: 212-218, 1997
34. TANAKA, Y.; H. NAKANO, F. ISHIKAWA, M. YOSHIDA, Y. GYOTOKU & T. KAKIUCHI: Cholera toxin increases intracellular pH in B lymphoma cells and decreases their antigen-presenting ability. Eur. J. Immunol. 29: 1561-1570, 1999
35. BROWN, B. K. & W. SONG: The actin cytoskeleton is required for the trafficking of the B cell antigen receptor to the late endosomes. Traffic 2: 414-427, 2001
36. VILLADANGOS, J. A.; R. A. R. BRYANT, J. DEUSSING, C. DRIESSEN, A.-M. LENNON-DUMENIL, R. J. RIESE, W. ROTH, P. SAFTIG, G.-P. SHI, H. A. CHAPMAN, C. PETERS & H. L. PLOEGH: Proteases involved in MHC class II antigen presentation. Immunol. Rev. 172: 109-120, 1999
37. SALISBURY, J. L.; J. S. CONDEELIS & P. SATIR: Role of coated vesicles, microfilaments, and calmodulin in receptor-mediated endocytosis by cultured B lymphoblastoid cells. J. Cell Biol. 87: 132-141, 1980
38. MELAMED, I.; G. P. DOWNEY & C. M. ROIFMAN: Tyrosine phosphorylation is essential for microfilament assembly in B lymphocytes. Biochem. Biophys. Res. Commun. 176: 1424-1429, 1991
39. BAROIS, N.; F. FORQUET & J. DAVOUST: Actin microfilaments control the MHC class II antigen presentation pathway in B cells. J. Cell Sci. 111: 1791-1800, 1998
40. CLAGUE, M. J.; S. URBE, F. ANIENTO & J. GRUENBERG: Vacuolar ATPase activity is required for endosomal carrier vesicle formation. J. Biol. Chem. 269: 21-24, 1994
41. DROSE, S. & K. ALTENDORF: Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases. J. Exp. Biol. 200: 1-8, 1997