B lymphocytes as antigen-presenting cells for CD4+ T cell priming in vivo

Journal of Immunology

Volumn 162, Issue 10, 1999, Pages 5695-5703

  Constant, Stephanie L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL INTERACTION; HELPER CELL; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0033563084     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Healy, J. I., and C. C. Goodnow. 1998. Positive versus negative signaling by lymphocyte antigen receptors. Annu. Rev. Immunol. 16:645.
2. Ashwell, J. D. 1988. Are B lymphocytes the principal antigen-presenting cells in vivo? J. Immunol. 140:3697.
3. + T lymphocytes to peptide antigen in vivo. J. Immunol. 151:6742.
4. Wilson, J. L., A. C. Cunningham, and J. A. Kirby. 1995. Alloantigen presentation by B cells: analysis of the requirement for B-cell activation. Immunology 86:325.
5. Lassila, O., S. Vainio, and P. Matzinger. 1988. Can B cells turn on virgin T cells? Nature 334:253.
6. Eynon, E. E., and D. C. Parker. 1992. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J. Exp. Med. 175:131.
7. Noelle, R. J., E. C. Snow, J. W. Uhr, and E. S. Vitetta. 1983. Activation of antigen-specific B cells: role of T cells, cytokines, and antigen in induction of growth and differentiation. Proc. Natl. Acad. Sci. USA 80:6628.
8. Grewal, I. S., and R. A. Ravell. 1998. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16:111.
9. Inaba, K., and R. M. Steinman. 1984. Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release. J. Exp. Med. 160:1717.
10. Croft, M., and S. L. Swain. 1991. B cell response to fresh and effector helper T cells: a role of cognate T-B interaction and the cytokines IL-2, IL-4, and IL-6. J. Immunol. 146:4055.
11. Fuchs, F. J., and P. Matzinger. 1992. B cells turn off virgin but not memory T cells. Science 258:1156.
12. + T cell activation but both are required for optimum response. J. Immunol. 155:45.
13. Eynon, E. E., and D. C. Parker. 1993. Parameters of tolerance induction by antigen targeted to B lymphocytes. J. Immunol. 151:2958.
14. Morris, S. C., A. Lees, and F. D. Finkelman. 1994. In vivo activation of naive T cells by anitgen-presenting B cells. J. Immunol. 152:3777.
15. + T cells to protein antigens in vivo. J. Immunol. 155:3734.
16. Goodnow, C. C., J. Crosbie, S. Adelstein,T. B. Lavoie, S. J. Smith-Gill, R. Brink, H. Pritchard-Briscoe, J. Wotherspoon, R. Loblay, K. Raphael, R. Trent, and A. Basten. 1988. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334:676.
17. + T cells in transgenic mice express a class II MHC restricted antigen receptor. Nature 341:746.
18. Xu, J., T. M. Foy, J. D. Laman, E. A. Elliott, J. J. Dunn, T. J. Waldschmidt, J. Elsemore, R. J. Noelle, and R. A. Flavell. 1994. Mice deficient for the CD40 ligand. Immunity 1:423.
19. Lyons, A. B., and C. R. Parish. 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171:131.
20. + T cells. J. Immunol. 154:4915.
21. Garside, P., E. Ingulli, R. R. Merica. J. G. Johnson, R. J. Noelle, and M. K. Jenkins. 1998. Visualization of specific B and T lymphocyte interactions in the lymph node. Science 281:96.
22. Stossel, H., F. Koch, E. Kampgen, P. Stoger, A. Lenz, C. Heufler, N. Romani, and G. Schuler. 1990. Disappearance of certain acidic organelles (endosomes and Langerhans cell granules) accompanies loss of antigen processing capacity upon culture of epidermal Langerhans cells. J. Exp. Med. 172:1471.
23. Knight, S. C., and A. J. Stagg. 1993. Antigen-presenting cell types. Curr. Opin. Immunol. 5:374.
24. Jiang, W., W. J. Swiggard, C. Heufler, M. Peng, A. Mirza, R. M. Steinman, and M. C. Nussenzweig. 1995. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375:151.
25. Banchereau, J., F. Bazan, D. Blanchard, F. Briere, J. P. Galizzi, C. van Kooten, Y. J. Liu, F. Rousset, and S. Saeland. 1994. The CD40 antigen and its ligand. Annu. Rev. Immunol. 12:881.
26. Grabstein, K. H., C. R. Maliszewski, K. Shanebeck, T. A. Sato, M. K. Spriggs, W. C. Fanslow, and R. J. Armitage. 1993. The regulation of T cell-dependent antibody formation in vitro by CD40 ligand and IL-2. J. Immunol. 150:3141.
27. Roy, M., A. Aruffo, J. Ledbetter, P. Linsley, M. Kehry, and R. Noelle. 1995. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. Eur. J. Immunol. 25:596.
28. Lenschow, D. J., A. I. Sperling, M. P. Cooke, G. Freeman, L. Rhee, D. C. Decker, G. Gray, L. M. Nadler, C. C. Goodnow, and J. A. Bluestone. 1994. Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen. J. Immunol. 153:1990.
29. Grewal, I. S., J. Xu, and R. A. Flavell. 1995. Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. Nature 378:617.
30. Song, W., H. Cho, P. Cheng, and S. K. Pierce. 1995. Entry of B cell antigen receptor and antigen into class II peptide-loading compartment is independent of receptor cross-linking. J. Immunol. 155:4255.
31. Cyster, J. G., and C. C. Goodnow, 1995. Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate. Immunity 3:691.
32. Fulcher, D. A., A. B. Lyons, S. L. Korn, M. C. Cook, C. Koleda, C. Parish, B. Fazekas de St. Groth, and A. Basten. 1996. The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help. J. Exp. Med. 183:2313.
33. Fournier, S., J. C. Rathmell, C. G. Goodnow, and J. P. Allison. 1997. T cell-mediated elimination of B7.2 transgenic B cells. Immunity 6:327.
34. Townsend, S. E., and C. C. Goodnow. 1998. Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo. J. Exp. Med. 187:1611.
35. Klinman, N. R., and J. L. Press. 1975. The B cell specificity repertoire: its relationship to definable subpopulations. Transplant. Rev. 24:41.
36. Liu, Y. J., J. Zhang, P. J. L. Lane, E. Y. T. Chan, and I. C. M. MacLennan. 1991. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21:2951.