Therapeutic liabilities of in vivo viral vector tropism: Adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity

Molecular Therapy

Volumn 6, Issue 4, 2002, Pages 495-500

  Haberman, Rebecca P ^a   Criswell, Hugh E ^a,b   Snowdy, Stephen ^b   Ming, Zhen ^a   Breese, George R ^a,b   Samulski, R Jude ^a   McCown, Thomas J ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

AAV; Antisense; Gene therapy; NMDA; Promoters; Seizures; Tropism

Indexed keywords

BETA GALACTOSIDASE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; GREEN FLUORESCENT PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TETRACYCLINE; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL POPULATION; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG ACTIVITY; EFFERENT NERVE; FOCAL EPILEPSY; GENE EXPRESSION; IMMUNOREACTIVITY; IN VIVO STUDY; INFERIOR COLLICULUS; INTERNEURON; MOLECULAR CLONING; NERVE CELL CULTURE; NERVE CONDUCTION; NONHUMAN; NUCLEIC ACID PROBE; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PROMOTER REGION; PYRAMIDAL NERVE CELL; RAT; SEIZURE SUSCEPTIBILITY; TEMPORAL CORTEX; VIRAL GENE THERAPY;

ADENO-ASSOCIATED VIRUS; ANIMALIA; CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS;

EID: 0036798809     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2002.0701     Document Type: Article

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