Plasticity-associated molecular and structural events in the injured brain

Journal of Neuropathology and Experimental Neurology

Volumn 61, Issue 10, 2002, Pages 831-840

  Keyvani, Kathy ^a   Schallert, Timothy ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Experience induced plasticity; Genes; Lesion induced plasticity; Morphology

Indexed keywords

CELL ADHESION MOLECULE; GROWTH FACTOR; NEUROTRANSMITTER RECEPTOR; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR;

BRAIN INJURY; CYTOSKELETON; DENDRITIC CELL; DENSITY; GROWTH CONE; LEARNING; NERVE CELL PLASTICITY; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SPINE; SYNAPSE; SYNAPTOGENESIS;

EID: 0036795330     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/61.10.831     Document Type: Review

References (100)

1. Soltmann O. Experimentelle Studien über die Functionen des Grosshims der Neugeborenen. Jahrb Kinderheilkd 1876;9:106-48
2. Hebb DO. The organization of behavior. New York: Wiley, 1949
3. Schallert T, Leasure JL, Kolb B. Experience-associated structural events, subependymal cellular proliferative activity, and functional recovery after injury to the central nervous system. J Cereb Blood Flow Metab 2000;20:1513-28
4. Nudo RJ, Plautz EJ, Frost SB. Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle Nerve 2001; 24:1000-1019
5. Whishaw IQ. Loss of the innate cortical engram for action patterns used in skilled reaching and the development of behavioral compensation following motor cortex lesions in the rat. Neuropharmacology 2000;39:788-805
6. Jones TA. Multiple synapse formation in the motor cortex opposite unilateral sensorimotor cortex lesions in adult rats. J Comp Neurol 1999;414:57-66
7. Harris KM. How multiple-synapse boutons could preserve input specificity during an interneuronal spread of LTP. Trends Neurosci 1995;18:365-69
8. Jones TA, Chu CJ, Grande LA, Gregory AD. Motor skills training enhances lesion-induced structural plasticity in the motor cortex of adult rats. J Neurosci 1999;19:10153-63
9. Schallert T, Kozlowski DA, Humm JL, Cocke RR. Use-dependent structural events in recovery of function. Adv Neurol 1997;73:229-38
10. Johansson BB, Belichenko PV. Neuronal plasticity and dendritic spines: Effect of environmental enrichment on intact and postischemic rat brain. J Cereb Blood Flow Metab 2002;22:89-96
11. Taub E, Uswatte G, Elbert T. New treatment in neurorehabilitation founded on basic research. Nature 2002;3:228-36
12. Bland ST, Schallert T, Strong R, et al. Early exclusive use of the affected forelimb after moderate transient focal ischemia in rats: Functional and anatomic outcome. Stroke 2000;31:1144-52
13. Gage FH. Neurogenesis in the adult brain. J Neurosci 2002;22:612-13
14. Zhang RL, Zhang ZG, Zhang L, Chopp M. Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neuroscience 2001;105:33-41
15. Takasawa KK, Kitagawa K, Yagita Y, et al. Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2002;22:299-307
16. Hsu CY, An G, Liu JS, et al. Expression of immediate early gene and growth factor mRNAs in a focal cerebral ischemia model in the rat. Stroke 1993;24:178
17. Honkaniemi J, States BA, Weinstein PR, Espinoza J, Sharp FR. Expression of zinc finger immediate early genes in rat brain after permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab 1997;17:636-46
18. Keyvani K, Witte OW, Paulus W. Gene expression profiling in perilesional and contralateral areas after ischemia in rat brain. J Cereb Blood Flow Metab 2002;22:153-60
19. Johansson IM, Wester P, Hakova M, et al. Early and delayed induction of immediate early gene expression in a novel focal cerebral ischemia model in the rat. Eur J Neurosci 2000;12:3615-25
20. Herdegen T, Leah JD. Inducible and constitutive transcription factors in the mammalian nervous system: Control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Rev 1998;28:370-490
21. Soriano MA, Tessier M, Certa U, Gill R. Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. J Cereb Blood Flow Metab 2000;20:1045-55
22. Lyford GL, Yamagata K, Kaufmann WE, et al. Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 1995; 14:433-45
23. Tanaka K, Nagata E, Suzuki S, et al. Immunohistochemical analysis of cyclic AMP response element binding protein phosphorylation in focal cerebral ischemia in rats. Brain Res 1999;818:520-26
24. Tanaka K, Nogawa S, Ito D, et al. Phosphorylation of cyclic adenosine monophosphate response element binding protein in oligodendrocytes in the corpus callosum after focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 2001;21:1177-88
25. Walton MR, Dragunow I. Is CREB a key to neuronal survival? Trends Neurosci 2000;23:48-53
26. Kandel ER. The molecular biology of memory storage: A dialogue between genes and synapses. Science 2001;294:1030-38
27. Barth AL, McKenna M, Glazewski S, et al. Upregulation of cAMP response element-mediated gene expression during experience-dependent plasticity in adult neocortex. J Neurosci 2000;20:4206-16
28. Sharp FR, Lu A, Tang Y. Millhorn DE. Multiple molecular penumbras after focal cerebral ischemia. J Cereb Blood Flow Metab 2000;20:1011-32
29. Albensi BC, Mattson MP. Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity. Synapse 2000; 35:151-59
30. Wu DC. Ye W, Che XM, Yang GY. Activation of mitogen-activated protein kinases after permanent cerebral artery occlusion in mouse brain. J Cereb Blood Flow Metab 2000;20:1320-30
31. Onodera H, Yamasaki Y, Kogure K, Miyamoto E. Calcium/calmodulin-dependent protein kinase II and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus long after ischemia. Brain Res 1995;684:95-98
32. 2+/calmodulin-dependent protein kinase II and calcineurin in the hippocampus of rat brain after transient forebrain ischemia. J Neurochem 1992;58:1798-1809
33. Soderling TR. The Ca-calmodulin-dependent protein kinase cascade. Trends Biochem Sci 1999;24:232-36
34. Nicole O, Ali C, Docagne F, et al. Neuroprotection mediated by glial cell line-derived neurotrophic factor: Involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway. J Neurosci 2001;21:3024-33
35. Friedman LK, Ginsberg MD, Belayev L, et al. Intraischemic but not postischemic hypothermia prevents non-selective hippocampal downregulation of AMPA and NMDA receptor gene expression after global ischemia. Mol Brain Res 2001;86:34-47
36. Qu M, Mittmann T, Luhmann HJ, Schleicher A, Zilles K. Long-term changes of ionotropic glutamate and GABA receptors after unilateral permanent focal cerebral ischemia in the mouse brain. Neuroscience 1998;85:29-43
37. Que M, Schiene K, Witte OW, Zilles K. Widespread up-regulation of N-methyl-D-aspartate receptors after focal photothrombotic lesion in rat brain. Neurosci Lett 1999;273:77-80
38. Iversen L, Mulvihill E, Haldeman B, et al. Changes in metabotropic glutamate receptor mRNA levels following global ischemia: increase of a putative presynaptic subtype (mGluR4) in highly vulnerable rat brain areas. J Neurochem 1994;63:625-33
39. Keyvani K, Bosse F, Reinecke S, Paulus W, Witte OW. Postlesional transcriptional regulation of metabotropic glutamate receptors: Implications for plasticity and excitotoxicity. Acta Neuropathol 2001; 101:79-84
40. Meldrum BS. Excitatory amino acid receptors and their role in epilepsy and cerebral ischemia. Ann N Y Acad Sci 1995;757:492-505
41. Shapiro M. Plasticity, hippocampal place cells, and cognitive maps. Arch Neurol 2001;58:874-81
42. Luscher C, Xia H, Beattie EC, et al. Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 1999;24:649-58
43. Bortolotto ZA, Clarke VR, Delany CM, et al. Kainate receptors are involved in synaptic plasticity. Nature 1999;402:297-301
44. Bortolotto ZA, Fitzjohn SM, Collingridge GL. Roles of metabotropic glutamate receptors in LTP and LTD in the hippocampus. Curr Opin Neurobiol 1999;9:299-304
45. Alicke B, Schwartz-Bloom RD. Rapid down-regulation of GABAA receptors in the gerbil hippocampus following transient cerebral ischemia. J Neurochem 1995;65:2808-11
46. Witte OW, Bidmon HJ, Schiene K, Redecker C, Hagemann G. Functional differentiation of multiple perilesional zones after focal cerebral ischemia. J Cereb Blood Flow Metab 2000;20:1149-65
47. Kokaia Z, Andsberg G, Yan Q, Lindvall O. Rapid alterations of BDNF protein levels in the rat brain after focal ischemia: Evidence for increased synthesis and anterograde axonal transport. Exp Neurol 1998;154:289-301
48. Arai S, Kinouchi H, Akabane A, et al. Induction of brain-derived neurotrophic factor (BDNF) and the receptor trk B mRNA following middle cerebral artery occlusion in rat. Neurosci Lett 1996;211: 57-60
49. Takeda A, Onodera H, Sugimoto A, et al. Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia. Neuroscience 1993;55:23-31
50. Lee TH, Kato H, Kogure K, Itoyama Y. Temporal profile of nerve growth factor-like immunoreactivity after focal cerebral ischemia in rats. Brain Res 1996;713:199-210
51. Lin TN, Te J, Lee M, Sun GY, Hsu CY. Induction of basic fibroblast growth factor (bFGF) expression following focal cerebral ischemia. Mol Brain Res 1997;49:255-65
52. Miyazaki H, Nagashima K, Okuma Y, Nomura Y. Expression of glial cell line-derived neurotrophic factor induced by transient forebrain ischemia in rats. Brain Res 2001;20;922:165-72
53. Iihara K, Sasahara M, Hashimoto N, et al. Ischemia induces the expression of the platelet-derived growth factor-B chain in neurons and brain macrophages in vivo. J Cereb Blood Flow Metab 1994; 14:818-24
54. Garcia-Estrada J, Garcia-Segura LM, Torres-Aleman I. Expression of insulin-like growth factor I by astrocytes in response to injury. Brain Res 1992;592:343-47
55. Lehrmann E, Kiefer R, Christensen T, et al. Microglia and macrophages are major sources of locally produced transforming growth factor-beta1 after transient middle cerebral artery occlusion in rats. Glia 1998;24:437-48
56. Beck H, Acker T, Puschel AW, et al. Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling. J Neuropathol Exp Neurol 2002;61:339-50
57. Mattson MP. Trophic factors and brain cell survival. In: Welch KM, Caplan LR, Reis DJ, eds. Primer on cerebrovascular diseases. Portland: Academic Press, 1999:237-39
58. McAllister AK, Katz LC, Lo DC. Neurotrophins and synaptic plasticity. Annu Rev Neurosci 1999;22:295-318
59. Zhai QH, Futrell N, Chen FJ. Gene expression of IL-10 in relationship to TNF-α, IL-1β and IL-2 in the rat brain following middle cerebral artery occlusion. J Neurol Sci 1997;152:119-24
60. Koistinaho J, Pyykonen I, Keinanen R, Hokfelt T. Expression of beta-amyloid precursor protein mRNAs following transient focal ischaemia. Neuroreport 1996;7:2727-31
61. Kim JH, Anwyl R, Suh YH, Djamgoz MB, Rowan MJ. Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo. J Neurosci 2001;21:1327-33
62. Stroemer RP, Kent TA, Hulsebosch CE. Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke 1995;26:2135-44
63. Tagaya M, Matsuyama T, Nakamura H, et al. Increased FI/GAP-43 mRNA accumulation in gerbil hippocampus after brain ischemia. J Cereb Blood Flow Metab 1995;15:1132-36
64. McNeill TH, Mori N, Cheng HW. Differential regulation of the growth-associated proteins, GAP-43 and SCG-10, in response to unilateral cortical ablation in adult rats. Neuroscience 1999;90: 1349-60
65. Li Y, Jiang N, Powers C, Chopp M. Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43, and cyclin DI immunoreactivity after focal cerebral ischemia in rats. Stroke 1998;29:1972-80
66. Poirier J, Hess M, May PC, Finch CE. Cloning of hippocampal poly(A) RNA sequences that increase after entorhinal cortex lesion in adult rat. Mol Brain Res 1991;9:191-95
67. Kitagawa K, Matsumoto M, Kuwabara K, Ohtsuki T, Hori M. Delayed, but marked, expression of apolipoprotein E is involved in tissue clearance after cerebral infarction. J Cereb Blood Flow Metab 2001;21:1199-207
68. Franz G, Reindl M, Patel SC, et al. Increased expression of apolipoprotein D following experimental traumatic brain injury. J Neurochem 1999;73:1615-25
69. Terrisse L, Seguin D, Bertrand P, et al. Modulation of apolipoprotein D and apolipoprotein E expression in rat hippocampus after entorhinal cortex lesion. Mol Brain Res 1999;70:26-35
70. Masliah E, Mallory M, Veinbergs I, Miller A, Samuel W. Alterations in apolipoprotein E expression during aging and neurodegeneration. Prog Neurobiol 1996;50:493-503
71. Marti E, Ferrer I, Blasi J. Transient increase of synapsin-I immunoreactivity in the mossy fiber layer of the hippocampus after transient forebrain ischemia in the mongolian gerbil. Brain Res 1999; 824:153-60
72. Lapchak PA, Araujo DM, Beck KD, et al. BDNF and trkB mRNA expression in the hippocampal formation of aging rats. Neurobiol Aging 1993;14:121-26
73. Hayashi T, Seki T, Sato K, et al. Expression of polysialylated neural cell adhesion molecule in rat brain after transient middle cerebral artery occlusion. Brain Res 2001;907:130-33
74. Sato K, Hayashi T, Sasaki C, et al. Temporal and spatial differences of PSA-NCAM expression between young-adult and aged rats in normal and ischemic brains. Brain Res 2001;922:135-39
75. Fox GB, Kjoller C, Murphy KJ, Regan CM. The modulations of NCAM polysialylation state that follow transient global ischemia are brief on neurons but enduring on glia. J Neuropathol Exp Neurol 2001;60:132-40
76. Styren SD, Miller PD, Lagenaur CF, DeKosky ST. Alternate strategies in lesion-induced reactive synaptogenesis: Differential expression of L1 in two populations of sprouting axons. Exp Neurol 1995;131:165-73
77. Cho H, Shimazaki K, Takeuchi K, et al. Biphasic changes in F3/contactin expression in the gerbil hippocampus after transient ischemia. Exp Brain Res 1998;122:227-34
78. Deller T, Haas CA, Naumann T, et al. Up-regulation of astrocyte-derived tenascin-C correlates with neurite outgrowth in the rat dentate gyrus after unilateral entorhinal cortex lesion. Neuroscience 1997;81:829-46
79. Jin K, Mao XO. Eshoo MW, et al. Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann Neurol 2001;50:93-103
80. Ying G, Huang C, Jing N, Zhou C. Identification of differentially expressed genes in the denervated rat hippocampus by cDNA arrays. Neurosci Lett 2001;306:121-25
81. Staiger JF, Bisler S, Schleicher A, et al. Exploration of a novel environment leads to the expression of inducible transcription factors in barrel-related columns. Neuroscience 2000;99:7-16
82. Rose SP. God's organism? The chick as a model system for memory studies. Learn Mem 2000;7:1-17
83. Malkani S, Rosen JB. Induction of NGFI-B mRNA following contextual fear conditioning and its blockade by diazepam. Mol Brain Res 2000;80:153-65
84. Mack KJ, Yi SD, Chang S, Millan N, Mack P. NGFI-C expression is affected by physiological stimulation and seizures in the somatosensory cortex. Mol Brain Res 1995;29:140-46
85. Pinaud R, Penner MR, Robertson HA, Currie RW. Upregulation of the immediate early gene arc in the brains of rats exposed to environmental enrichment: Implications for molecular plasticity. Mol Brain Res 2001;91:50-6
86. Freudenthal R, Romano A. Participation of Rel/NF-kappaB transcription factors in long-term memory in the crab Chasmagnathus. Brain Res 2000;855:274-81
87. Schafe GE, Atkins CM, Swank MW, et al. Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning. J Neurosci 2000;20:8177-87
88. Tong L, Shen H, Perreau VM, Balazs R, Cotman CW. Effects of exercise on gene-expression profile in the rat hippocampus. Neurobiol Dis 2001;8:1046-56
89. Tang YP, Wang H, Feng R, Kyin M, Tsien JZ. Differential effects of enrichment on learning and memory function in NR2B transgenic mice. Neuropharmacology 2001;41:779-90
90. Aultman JM, Moghaddam B. Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task. Psychopharmacology (Berl) 2001;153:353-64
91. Jasnow AM, Huhman KL. Activation of GABA(A) receptors in the amygdala blocks the acquisition and expression of conditioned defeat in Syrian hamsters. Brain Res 2001;920:142-50
92. Ickes BR, Pham TM, Sanders LA, et al. Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain. Exp Neurol 2000;164:45-52
93. Gomez-Pinilla F, So V, Kesslak JP. Spatial learning and physical activity contribute to the induction of fibroblast growth factor: Neural substrates for increased cognition associated with exercise. Neuroscience 1998;85:53-61
94. Young D, Lawlor PA, Leone P, Dragunow M, During MJ. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med 1999;5:448-53
95. Gomez-Pinilla F, So V, Kesslak JP. Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus. Brain Res 2001;904:13-19
96. Quattrone A, Pascale A, Nogues X, et al. Post-transcriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins. Proc Natl Acad Sci U S A 2001;98: 11668-73
97. Scholey AB, Bullock S, Rose SP. Passive avoidance learning in the young chick results in time- and locus-specific elevations of alphatubulin immunoreactivity. Neurochem Int 1992;21:343-50
98. Van der Zee EA, Douma BR. Bohus B, Luiten PG. Passive avoidance training induces enhanced levels of immunoreactivity for muscarinic acetylcholine receptor and coexpressed PKC gamma and MAP-2 in rat cortical neurons. Cereb Cortex 1994;4:376-90
99. Nakamura H, Kobayashi S, Ohashi Y. Ando S. Age-changes of brain synapses and synaptic plasticity in response to an enriched environment. J Neurosci Res 1999;56:307-15
100. Murphy KJ, Regan CM. Sequential training in separate paradigms impairs second task consolidation and learning-associated modulations of hippocampal NCAM polysialylation. Neurobiol Learn Mem 1999;72:28-38