Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase β in human peripheral blood mononuclear cells

European Journal of Biochemistry

Volumn 264, Issue 3, 1999, Pages 952-959

  Ahlers, Christoph ^d   Kreideweiß, Stefan ^a   Nordheim, Alfred ^c   Rühlmann, Andreas ^b  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d NONE

Author keywords

Ca2+ mediated signal transduction; Cyclosporin A; DNA repair; Immunosuppression

Indexed keywords

CALCINEURIN; CALCIUM ION; CYCLOSPORIN A; DNA DIRECTED DNA POLYMERASE BETA; IONOMYCIN; TACROLIMUS; CALCIUM; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; IONOPHORE; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PRIMER DNA;

ARTICLE; CANCER INCIDENCE; DNA REPAIR; ENZYME INDUCTION; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; DRUG EFFECT; GENETICS; IN VITRO STUDY; METABOLISM; NEOPLASM; NUCLEOTIDE SEQUENCE; UPREGULATION;

ANIMALS; BASE SEQUENCE; CALCINEURIN; CALCIUM; CYCLOSPORINE; DNA POLYMERASE BETA; DNA PRIMERS; DNA REPAIR; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IONOMYCIN; IONOPHORES; LEUKOCYTES, MONONUCLEAR; NEOPLASMS; RNA, MESSENGER; TACROLIMUS; TETRADECANOYLPHORBOL ACETATE; UP-REGULATION;

EID: 0033194959     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00700.x     Document Type: Article

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