Transfection with aFGF cDNA improves wound healing

Journal of Investigative Dermatology

Volumn 108, Issue 3, 1997, Pages 313-318

  Sun, Liying ^a   Xu, Lan ^a   Chang, Henry ^a   Henry, Fleetwood A ^a   Miller, Robert M ^a   Harmon, John M ^b,c   Nielsen, Thor B ^a,c  

^a NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

cytokine expression; diabetic mice; gene therapy

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; RECOMBINANT ACIDIC FIBROBLAST GROWTH FACTOR;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE THERAPY; GENE TRANSFER; HISTOLOGY; IMMUNOBLOTTING; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; RNA TRANSCRIPTION; TOPICAL DRUG ADMINISTRATION; WOUND HEALING;

EID: 0031043724     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12286471     Document Type: Article

References (37)

1. Anderson WF: Human gene therapy. Science 256:808-813, 1992
2. Andree C, Swain WF, Page CP, Macklin MD, Slama J, Hatzis D, Eriksson E: In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair. Proc Natl Acad Sci USA 91:12188-12192, 1994
3. Barr E, Leiden JM: Systemic delivery of recombinant proteins by genetically modified myoblasts. Science 254:1507-1509, 1991
4. Brown GL, Curtsinger L, Jurkiewicz MJ, Nahai F, Schultz G: Stimulation of healing of chronic wounds by epidermal growth factor. Plast Reconstr Surg 88:189-194, 1991
5. Brown RL, Breeden MP, Greenhalgh DG: PDGF and TGF-α act synergistically to improve wound healing in the genetically diabetic mouse. J Surg Res 56:562-570, 1994
6. Burgess WH, Mehlman T, Marshak DR, Fraser BA, Maciag T: Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor. Proc Natl Acad Sci USA 83:7216-7220, 1986
7. Chen JK, Haimes HB, Weinberg CB: Role of growth factors in the contraction and maintenance of collagen lattices made with arterial smooth muscle cells. J Cell Physiol 146:110-116, 1991
8. Colombo MP, Ferrari G, Stoppacciaro A, Parenza M, Rodolfo M, Mavilio F, Parmiani G: Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo. J Exp Med 173:889-897, 1991
9. Committee on Care and Use of Laboratory Animals: Guide for the Care and Use of Laboratory Animals. DDHS Publ. No. (NIH) 85-23. National Institutes of Health, Bethesda, MD, 1985
10. Dabin I, Courtois Y: Acidic fibroblast growth factor overexpression in corneal epithelial wound healing. Growth Factors 5:129-139, 1991
11. Danko I, Fritz JD, Jiao S, Hogan K, Latendresse JS, Wolff JA: Pharmacological enhancement of in vivo foreign gene expression in muscle. Gene Therapy 1:114-121, 1994
12. Federoff HJ, Geschwind MD, Geller AI, Kessler JA: Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia. Proc Natl Acad Sci USA 89:1636-1640, 1992
13. Fitzpatrick LR, Jakubowska A, Martin GE, Davis M, Jaye MC, Dionne CA: Acidic fibroblast growth factor accelerates the healing of acetic-acid-induced gastric ulcers in rats. Digestion 53:17-27, 1992
14. Forough R, Xi Z, MacPhee M, Friedman S, Engleka KA, Sayers T, Wiltrout RH, Maciag T: Differential transforming abilities of non-secreted and secreted forms of human fibroblast growth factor-1. J Biol Chem 268:2960-2968, 1993
15. Greenhalgh DA, Rothnagel JA, Roop DR: Epidermis: an attractive target tissue for gene therapy. J Invest Dermatol 103:63S-69S, 1994
16. Greenhalgh DG, Sprugel KH, Murray MJ, Ross R: PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am J Pathol 136:1235-1246, 1990
17. Gutierrez AA, Lemoine NR, Sikora K: Gene therapy for cancer. Lancet 339:715-721, 1992
18. Imamura T, Engleka K, Zhan X, Tokita Y, Forough R, Roeder D, Jackson A, Maier JA, Hla T, Maciag T: Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. Science 249:1567-1570, 1990
19. Jackson A, Friedman S, Zhan X, Engleka KA, Forough R, Matiag T: Heat shock induces the release of fibroblast growth factor 1 from NIH 3T3 cells. Proc Natl Acad Sci USA 89:10691-10695, 1992
20. Klein-Soyer C, Archipoff G, Beretz A, Cazenave JP: Opposing effects of heparin with TGF-beta or aFGF during repair of a mechanical wound of human endothelium. Influence of cAMP on cell migration. Biol Cell 75:155-162, 1992
21. Krueger GG, Morgan JR, Jorgensen CM, Schmidt L, Li HL, Kwan MK, Boyce ST, Wiley HS, Kaplan J, Petersen MJ: Genetically modified skin to treat disease: potential and limitations. J Invest Dermatol 103:76S-84S, 1994
22. Mason IJ: The ins and outs of fibroblast growth factors. Cell 78:547-552, 1994
23. Matuszewska B, Keogan M, Fisher DM, Soper KA, Hoe CM, Huber AC, Bondi JV: Acidic fibroblast growth factor: evaluation of topical formulations in a diabetic mouse wound healing model. Pharmacol Res 11:65-71, 1994
24. Mellin TN, Cashen DE, Ronan JJ, Murphy BS, diSalvo J, Thomas KA: Acidic fibroblast growth factor accelerates dermal wound healing in diabetic mice. J Invest Dermatol 104:850-855, 1995
25. Mellin TN, Mennie RJ, Cashen DE, Ronan JJ, Capparella J, James M, Disalvo J, Frank J, Linemeyer D, Gimenez-Gallego G, Thomas KA: Acidic fibroblast growth factor accelerates dermal wound healing. Growth Factors 7:1-14, 1992
26. Mignatti P, Morimoto T, Rifkin DB: Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J Cell Physiol 151:81-93, 1992
27. Mulligan RC: The basic science of gene therapy. Science 260:926-932, 1993
28. Raz E, Watanabe A, Baird SM, Eisenberg RA, Parr TB, Lotz M, Kipps TJ, Carson DA: Systemic immunological effects of cytokine genes injected into skeletal muscle. Proc Natl Acad Sci USA 90:4523-4527, 1993
29. Robson MC, Phillips LG, Thomason A, Robson LE, Pierce GF: Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. Lancet 339:23-25, 1992
30. Roemer K, Friedmann T: Concepts and strategies for human gene therapy. Eur J Biochem 208:211-225, 1992
31. Steed DI, Goslen JB, Holloway GA, Malone JM, Bunt TJ, Webster MW: Randomized prospective double-blind trial in healing chronic diabetic foot ulcers: CT-102 activated platelet supernatant, topical versus placebo. Diabetes Care 15:1598-1604, 1992
32. Sun L, Xu L, Henry FA, Spiegel S, Nielsen TB: A new wound healing agent: sphingosylphosphorylcholine. J Invest Dermatol 106:232-237, 1996
33. Tsuboi R, Rifkin DB: Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice. J Exp Med 172:245-251, 1990
34. Tsuboi R, Sato C, Shi CM, Ogawa H: Stimulation of keratinocyte migration by growth factors. J Dermatol 19:652-653, 1992
35. Vile R, Russell SJ: Gene transfer technologies for the gene therapy of cancer. Gene Therapy 1:88-98, 1994
36. Wang B, Ugen KE, Srikantan V, Agadjanyan MG, Dang K, Refaeli Y, Sato AI, Boyer J, Williams WV, Weiner DB: Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc Natl Acad Sci USA 90:4156-4160, 1993
37. Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A, Felgner PI : Direct gene transfer into mouse muscle in vivo. Science 247:1465-1468, 1990