메뉴 건너뛰기




Volumn 42, Issue 10, 2002, Pages 1159-1164

The effect of erythromycin and clarithromycin on the pharmacokinetics of intravenous digoxin in healthy volunteers

Author keywords

[No Author keywords available]

Indexed keywords

CLARITHROMYCIN; CYCLOSPORIN; DIGOSIN; DIGOXIN; ERYTHROMYCIN; FELODIPINE; ITRACONAZOLE; MACROLIDE; QUINIDINE; RIFAMPICIN; SIMVASTATIN; TALINOLOL; TRIAZOLAM; VERAPAMIL;

EID: 0036786390     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/009127002401382641     Document Type: Article
Times cited : (24)

References (45)
  • 1
    • 0031051347 scopus 로고    scopus 로고
    • The effect of digoxin on mortality and morbidity in patients with heart failure
    • The Digitalis Investigation Group: The effect of digoxin on mortality and morbidity in patients with heart failure. New Engl J Med 1997;336:525-533.
    • (1997) New Engl J Med , vol.336 , pp. 525-533
  • 2
    • 0029860174 scopus 로고    scopus 로고
    • Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr1a P-glycoprotein
    • Mayer U, Wagenaar E, Beijnen JH, Smit JW, Meijer DKG, van Asperen J, et al: Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr1a P-glycoprotein. Br J Pharmacol 1996;119:1038-1044.
    • (1996) Br J Pharmacol , vol.119 , pp. 1038-1044
    • Mayer, U.1    Wagenaar, E.2    Beijnen, J.H.3    Smit, J.W.4    Meijer, D.K.G.5    Van Asperen, J.6
  • 3
  • 4
    • 0029997940 scopus 로고    scopus 로고
    • Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells
    • Cavet ME, West M, Simmons NL: Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells. Br J Pharmacol 1996;118:1389-1396.
    • (1996) Br J Pharmacol , vol.118 , pp. 1389-1396
    • Cavet, M.E.1    West, M.2    Simmons, N.L.3
  • 5
    • 0026459449 scopus 로고
    • Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1)
    • Tanigawara Y, Okamura N, Hirai M, Yasuhara M, Ueda K, Kioka N, et al: Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). J Pharmacol Exp Ther 1992;263:840-845.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 840-845
    • Tanigawara, Y.1    Okamura, N.2    Hirai, M.3    Yasuhara, M.4    Ueda, K.5    Kioka, N.6
  • 6
    • 0010608710 scopus 로고
    • P-glycoprotein-mediated renal tubular secretion of digoxin: The toxicological significance of the urine-blood barrier model
    • Ito S, Woodland C, Harper PA, Koren G: P-glycoprotein-mediated renal tubular secretion of digoxin: the toxicological significance of the urine-blood barrier model. Life Sci 1993;53:PL25-31.
    • (1993) Life Sci , vol.53
    • Ito, S.1    Woodland, C.2    Harper, P.A.3    Koren, G.4
  • 7
    • 0027818964 scopus 로고    scopus 로고
    • Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney
    • 196
    • Hori R, Okamura N, Aiba T, Tanigawara Y: Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney. J Pharmacol Exp Ther 196;266:1620-1625.
    • J Pharmacol Exp Ther , vol.266 , pp. 1620-1625
    • Hori, R.1    Okamura, N.2    Aiba, T.3    Tanigawara, Y.4
  • 8
    • 9044245300 scopus 로고    scopus 로고
    • Inhibition of the intestinal digoxin absorption and exsorption by quinidine
    • Su S-F, Hung J-D: Inhibition of the intestinal digoxin absorption and exsorption by quinidine. Drug Metab Dispos 1996;24:142-146.
    • (1996) Drug Metab Dispos , vol.24 , pp. 142-146
    • Su, S.-F.1    Hung, J.-D.2
  • 9
    • 0027529288 scopus 로고
    • Quinidine enhances digitalis toxicity at therapeutic serum digoxin levels
    • Mordel A, Halkin H, Zulty L, Almog S, Ezra D: Quinidine enhances digitalis toxicity at therapeutic serum digoxin levels. Clin Pharmacol Ther 1993;52:457-462.
    • (1993) Clin Pharmacol Ther , vol.52 , pp. 457-462
    • Mordel, A.1    Halkin, H.2    Zulty, L.3    Almog, S.4    Ezra, D.5
  • 12
  • 14
    • 0027856015 scopus 로고
    • Digoxin-cyclosporin A interaction: Modulation of the multidrug transporter P-glycoprotein in the kidney
    • Okamura N, Hirai M, Tanigawara Y, Tanaka K, Yasuhara M, Ueda K, et al: Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney. J Pharmacol Exp Ther 1993;266:1614-1619.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 1614-1619
    • Okamura, N.1    Hirai, M.2    Tanigawara, Y.3    Tanaka, K.4    Yasuhara, M.5    Ueda, K.6
  • 15
    • 0026536295 scopus 로고
    • The effects of cardiac transplantation and cyclosporine therapy on digoxin pharmacokinetics
    • Robieux I, Dorian P, Klein J, Chung D, Zborowska-Sluiz D, Ogilvie R, et al: The effects of cardiac transplantation and cyclosporine therapy on digoxin pharmacokinetics. J Clin Pharmacol 1992;32:338-343.
    • (1992) J Clin Pharmacol , vol.32 , pp. 338-343
    • Robieux, I.1    Dorian, P.2    Klein, J.3    Chung, D.4    Zborowska-Sluiz, D.5    Ogilvie, R.6
  • 18
    • 0033865280 scopus 로고    scopus 로고
    • Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal P-glycoprotein
    • Westphal K, Weinbrenner A, Giessmann T, Stuhr M, Franke G, Zschiesche M, et al: Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein. Clin Pharmacol Ther 2000;68:6-12.
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 6-12
    • Westphal, K.1    Weinbrenner, A.2    Giessmann, T.3    Stuhr, M.4    Franke, G.5    Zschiesche, M.6
  • 19
    • 0031845356 scopus 로고    scopus 로고
    • Effect of clarithromycin on renal excretion of digoxin: Interaction with P-glycoprotein
    • Wakasugi H, Yano I, Ito H, Hashida T, Futami T, Nohara R, et al: Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. Clin Pharmacol Ther 1998;64:123-128.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 123-128
    • Wakasugi, H.1    Yano, I.2    Ito, H.3    Hashida, T.4    Futami, T.5    Nohara, R.6
  • 20
    • 0030775525 scopus 로고    scopus 로고
    • Clarithromycin-induced digoxin intoxication
    • Laberge P, Martineau P: Clarithromycin-induced digoxin intoxication. Ann Pharmacother 1997;31:999-1002.
    • (1997) Ann Pharmacother , vol.31 , pp. 999-1002
    • Laberge, P.1    Martineau, P.2
  • 22
    • 0024509893 scopus 로고
    • Digoxin toxicity due to interaction of digoxin with erythromycin
    • Maxwell DL, Gilmour-White SK, Hall MR: Digoxin toxicity due to interaction of digoxin with erythromycin. Br Med J 1989;298:572.
    • (1989) Br Med J , vol.298 , pp. 572
    • Maxwell, D.L.1    Gilmour-White, S.K.2    Hall, M.R.3
  • 23
    • 0022495594 scopus 로고
    • The significance of the enterohepatic circulation on the metabolism of digoxin in patients with the ability of intestinal conversion of the drug
    • Nørregaard-Hnawn K, Klitgaard NA, Pedersen KE: The significance of the enterohepatic circulation on the metabolism of digoxin in patients with the ability of intestinal conversion of the drug. Acta Med Scand 1986;220:89-92.
    • (1986) Acta Med Scand , vol.220 , pp. 89-92
    • Norregaard-Hnawn, K.1    Klitgaard, N.A.2    Pedersen, K.E.3
  • 24
    • 0024423702 scopus 로고
    • Erythromycin-induced digoxin toxicity
    • Morton MR, Cooper JW: Erythromycin-induced digoxin toxicity. Ann Pharmacother 1989;23:668-670.
    • (1989) Ann Pharmacother , vol.23 , pp. 668-670
    • Morton, M.R.1    Cooper, J.W.2
  • 26
  • 27
  • 28
    • 0032500849 scopus 로고    scopus 로고
    • Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells
    • Takano M, Hsegawa R, Fukuda T, Yumoto R, Nagai J, Murakami T: Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. Eur J Pharmacol 1998;358:289-294.
    • (1998) Eur J Pharmacol , vol.358 , pp. 289-294
    • Takano, M.1    Hsegawa, R.2    Fukuda, T.3    Yumoto, R.4    Nagai, J.5    Murakami, T.6
  • 29
    • 0032951089 scopus 로고    scopus 로고
    • Transport of rhodamine 123, a P-glycoprotein substrate, across intestine and Caco-2 cell monolayers in the presence of cytochrome P450 3A-related compounds
    • Yumoto R, Murakami T, Nakamoto Y, Hasegawa R, Nagai J, Takano M: Transport of rhodamine 123, a P-glycoprotein substrate, across intestine and Caco-2 cell monolayers in the presence of cytochrome P450 3A-related compounds. J Pharmacol Exp Ther 1999;289:149-155.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 149-155
    • Yumoto, R.1    Murakami, T.2    Nakamoto, Y.3    Hasegawa, R.4    Nagai, J.5    Takano, M.6
  • 30
    • 0030781139 scopus 로고    scopus 로고
    • Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833
    • Mayer U, Wagenaar E, Dorobek B, Beijnen JH, Borst P, Shinkel AH: Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. J Clin Invest 1997;100:2430-2436.
    • (1997) J Clin Invest , vol.100 , pp. 2430-2436
    • Mayer, U.1    Wagenaar, E.2    Dorobek, B.3    Beijnen, J.H.4    Borst, P.5    Shinkel, A.H.6
  • 31
    • 0030886124 scopus 로고    scopus 로고
    • Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
    • Noé B, Hagenbuch B, Stieger B, Meier PJ: Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci USA 1997;94:10346-10350.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10346-10350
    • Noé, B.1    Hagenbuch, B.2    Stieger, B.3    Meier, P.J.4
  • 33
    • 0019981880 scopus 로고
    • Renal digoxin clearance: Dependence on plasma digoxin and diuresis
    • Steiness E, Waldorf S, Hansen PB: Renal digoxin clearance: dependence on plasma digoxin and diuresis. Eur J Clin Pharmacol 1982;23:151-154.
    • (1982) Eur J Clin Pharmacol , vol.23 , pp. 151-154
    • Steiness, E.1    Waldorf, S.2    Hansen, P.B.3
  • 34
    • 0033678688 scopus 로고    scopus 로고
    • Atrovostatin coadministration may increase digoxin concentration by inhibition of intestinal P-glycoprotein-mediated secretion
    • Boyd RA, Stern RH, Stewart BH, Wu X, Reyner EL, Zegarac EA, et al: Atrovostatin coadministration may increase digoxin concentration by inhibition of intestinal P-glycoprotein-mediated secretion. J Clin Pharmacol 2000;40:91-98.
    • (2000) J Clin Pharmacol , vol.40 , pp. 91-98
    • Boyd, R.A.1    Stern, R.H.2    Stewart, B.H.3    Wu, X.4    Reyner, E.L.5    Zegarac, E.A.6
  • 35
    • 0026092531 scopus 로고
    • Digoxin-verapamil interaction: Reduction of biliary but not renal digoxin clearance in humans
    • Hedman A, Angelin B, Arvidsson A, Beck O, Dahlqvist R, Nilsson B, et al: Digoxin-verapamil interaction: reduction of biliary but not renal digoxin clearance in humans. Clin Pharmacol Ther 1991;49:256-262.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 256-262
    • Hedman, A.1    Angelin, B.2    Arvidsson, A.3    Beck, O.4    Dahlqvist, R.5    Nilsson, B.6
  • 37
    • 0026096151 scopus 로고
    • Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans
    • Hinderling PH, Hartman D: Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans. Ther Drug Monit 1991;13:381-401.
    • (1991) Ther Drug Monit , vol.13 , pp. 381-401
    • Hinderling, P.H.1    Hartman, D.2
  • 41
    • 0026740641 scopus 로고
    • Clarithromycin: A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential
    • Peters DH, Clissold SP: Clarithromycin: a review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential. Drugs 1992;44:117-164.
    • (1992) Drugs , vol.44 , pp. 117-164
    • Peters, D.H.1    Clissold, S.P.2
  • 42
    • 0021927474 scopus 로고
    • Pharmacokinetic interactions of the macrolide antibiotics
    • Ludden TM: Pharmacokinetic interactions of the macrolide antibiotics. Clin Pharmacokinet 1985;10:63-79.
    • (1985) Clin Pharmacokinet , vol.10 , pp. 63-79
    • Ludden, T.M.1
  • 43
    • 0029782647 scopus 로고    scopus 로고
    • Erythromycin-felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice
    • Bailey DG, Bend JR, Arnold MO, Tran LT, Spence JD: Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. Clin Pharmacol Ther 1996;60:25-33.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 25-33
    • Bailey, D.G.1    Bend, J.R.2    Arnold, M.O.3    Tran, L.T.4    Spence, J.D.5
  • 44
    • 13144257695 scopus 로고    scopus 로고
    • Inhibition of triazolam clearance by macrolide antimicrobial agents: In vitro correlates and dynamic consequences
    • Greenblat DJ, von Moltke LL, Harmatz JS, Counihan M, Graf JA, Durol ALB, et al: Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. Clin Pharmacol Ther 1998;64:278-285.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 278-285
    • Greenblat, D.J.1    Von Moltke, L.L.2    Harmatz, J.S.3    Counihan, M.4    Graf, J.A.5    Durol, A.L.B.6
  • 45
    • 0031670167 scopus 로고    scopus 로고
    • Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations
    • Kantola T, Kivistö KT, Neuvonen PJ: Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther 1998;64:177-182.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 177-182
    • Kantola, T.1    Kivistö, K.T.2    Neuvonen, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.