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Volumn 169, Issue 7, 2002, Pages 3811-3818

IL-4 induces the proteolytic processing of mast cell STAT6

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; INTERLEUKIN 4; STAT6 PROTEIN;

EID: 0036785569     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.7.3811     Document Type: Article
Times cited : (30)

References (74)
  • 1
    • 0030949167 scopus 로고    scopus 로고
    • STAT6: Its role in interleukin 4-mediated biological functions
    • Takeda, K., T. Kishimoto, and S. Akira. 1997. STAT6: its role in interleukin 4-mediated biological functions. J. Mol. Med. 75:317.
    • (1997) J. Mol. Med. , vol.75 , pp. 317
    • Takeda, K.1    Kishimoto, T.2    Akira, S.3
  • 4
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4:313.
    • (1996) Immunity , vol.4 , pp. 313
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 6
    • 0034544609 scopus 로고    scopus 로고
    • Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma
    • Ostrand-Rosenberg, S., M. J. Grusby, and V. K. Clements. 2000. Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma. J. Immunol. 165:6015.
    • (2000) J. Immunol. , vol.165 , pp. 6015
    • Ostrand-Rosenberg, S.1    Grusby, M.J.2    Clements, V.K.3
  • 7
    • 0034545618 scopus 로고    scopus 로고
    • Cutting edge: Spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice
    • Kacha, A. K., F. Fallarino, M. A. Markiewicz, and T. F. Gajewski. 2000. Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice. J. Immunol. 165:6024.
    • (2000) J. Immunol. , vol.165 , pp. 6024
    • Kacha, A.K.1    Fallarino, F.2    Markiewicz, M.A.3    Gajewski, T.F.4
  • 9
    • 0033662322 scopus 로고    scopus 로고
    • SOCS proteins, regulators of intracellular signaling
    • Chen, X. P., J. A. Losman, and P. Rothman. 2000. SOCS proteins, regulators of intracellular signaling. Immunity 13:287.
    • (2000) Immunity , vol.13 , pp. 287
    • Chen, X.P.1    Losman, J.A.2    Rothman, P.3
  • 10
    • 0033120880 scopus 로고    scopus 로고
    • Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
    • Losman, J. A., X. P. Chen, D. Hilton, and P. Rothman. 1999. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J. Immunol. 162:3770.
    • (1999) J. Immunol. , vol.162 , pp. 3770
    • Losman, J.A.1    Chen, X.P.2    Hilton, D.3    Rothman, P.4
  • 12
    • 0026725868 scopus 로고
    • Proteins of transcription factor ISGF-3: One gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon a
    • Schindler, C., X. Y. Fu, T. Improta, R. Aebersold, and J. E. Darnell, Jr. 1992. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon a. Proc. Natl. Acad. Sci. USA 89:7836.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7836
    • Schindler, C.1    Fu, X.Y.2    Improta, T.3    Aebersold, R.4    Darnell J.E., Jr.5
  • 13
    • 0027493650 scopus 로고
    • A single phosphotyrosine residue of Stat91 required for gene activation by interferon-γ
    • Shuai, K., G. R. Stark, I. M. Kerr, and J. E. Darnell, Jr. 1993. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-γ. Science 261:1744.
    • (1993) Science , vol.261 , pp. 1744
    • Shuai, K.1    Stark, G.R.2    Kerr, I.M.3    Darnell J.E., Jr.4
  • 15
    • 0030793345 scopus 로고    scopus 로고
    • Functionally distinct isoforms of STAT5 are generated by protein processing
    • Azam, M., C. Lee, I. Strehlow, and C. Schindler. 1997. Functionally distinct isoforms of STAT5 are generated by protein processing. Immunity 6:691.
    • (1997) Immunity , vol.6 , pp. 691
    • Azam, M.1    Lee, C.2    Strehlow, I.3    Schindler, C.4
  • 17
    • 0028963550 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
    • Mui, A. L., H. Wakao, A. M. O'Farrell, N. Harada, and A. Miyajima. 1995. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J. 14: 1166.
    • (1995) EMBO J. , vol.14 , pp. 1166
    • Mui, A.L.1    Wakao, H.2    O'Farrell, A.M.3    Harada, N.4    Miyajima, A.5
  • 19
    • 0034663045 scopus 로고    scopus 로고
    • Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing
    • Piazza, F., J. Valens, E. Lagasse, and C. Schindler. 2000. Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing. Blood 96:1358.
    • (2000) Blood , vol.96 , pp. 1358
    • Piazza, F.1    Valens, J.2    Lagasse, E.3    Schindler, C.4
  • 21
    • 0033105842 scopus 로고    scopus 로고
    • IL-4 preferentially activates a novel STAT6 isoform in mast cells
    • Sherman, M. A., V. H. Secor, and M. A. Brown. 1999. IL-4 preferentially activates a novel STAT6 isoform in mast cells. J. Immunol. 162:2703.
    • (1999) J. Immunol. , vol.162 , pp. 2703
    • Sherman, M.A.1    Secor, V.H.2    Brown, M.A.3
  • 22
    • 0033197954 scopus 로고    scopus 로고
    • Inhibition of kit expression by IL-4 and IL-10 in murine mast cells: Role of STAT6 and phosphatidylinositol 3′-kinase
    • Mirmonsef, P., C. P. Shelburne, C. Fitzhugh Yeatman II, H. J. Chong, and J. J. Ryan. 1999. Inhibition of kit expression by IL-4 and IL-10 in murine mast cells: role of STAT6 and phosphatidylinositol 3′-kinase. J. Immunol. 163:2530.
    • (1999) J. Immunol. , vol.163 , pp. 2530
    • Mirmonsef, P.1    Shelburne, C.P.2    Fitzhugh Yeatman C. II3    Chong, H.J.4    Ryan, J.J.5
  • 24
    • 0028141859 scopus 로고
    • Interleukin-4 inhibits the expression of kit and tryptase during stem cell factor-dependent development of human mast cells from fetal liver cells
    • Nilsson, G., U. Miettinen, T. Ishizaka, L. K. Ashman, A. M. Irani, and L. B. Schwartz. 1994. Interleukin-4 inhibits the expression of kit and tryptase during stem cell factor-dependent development of human mast cells from fetal liver cells. Blood 84:1519.
    • (1994) Blood , vol.84 , pp. 1519
    • Nilsson, G.1    Miettinen, U.2    Ishizaka, T.3    Ashman, L.K.4    Irani, A.M.5    Schwartz, L.B.6
  • 25
    • 0022006791 scopus 로고
    • Neoplastic transformation of mast cells by Abelson-MuLV: Abrogation of IL-3 dependence by a nonautocrine mechanism
    • Pierce, J. H., P. P. Di Fiore, S. A. Aaronson, M. Potter, J. Pumphrey, A. Scott, and J. N. Ihle. 1985. Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism. Cell 41:685.
    • (1985) Cell , vol.41 , pp. 685
    • Pierce, J.H.1    Di Fiore, P.P.2    Aaronson, S.A.3    Potter, M.4    Pumphrey, J.5    Scott, A.6    Ihle, J.N.7
  • 26
    • 0019445109 scopus 로고
    • Long-term in vitro culture of murine mast cells. II. Purification of a mast cell growth factor and its dissociation from TCGF
    • Yung, Y. P., R. Eger, G. Tertian, and M. A. Moore. 1981. Long-term in vitro culture of murine mast cells. II. Purification of a mast cell growth factor and its dissociation from TCGF. J. Immunol. 127:794.
    • (1981) J. Immunol. , vol.127 , pp. 794
    • Yung, Y.P.1    Eger, R.2    Tertian, G.3    Moore, M.A.4
  • 27
    • 0020038653 scopus 로고
    • Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line
    • Alt, F. W., N. Rosenberg, R. J. Casanova, E. Thomas, and D. Baltimore. 1982. Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line. Nature 296:325.
    • (1982) Nature , vol.296 , pp. 325
    • Alt, F.W.1    Rosenberg, N.2    Casanova, R.J.3    Thomas, E.4    Baltimore, D.5
  • 29
    • 0031204428 scopus 로고    scopus 로고
    • Identification of a STAT6 domain required for IL-4-induced activation of transcription
    • Lu, B., M. Reichel, D. A. Fisher, J. F. Smith, and P. Rothman. 1997. Identification of a STAT6 domain required for IL-4-induced activation of transcription. J. Immunol. 159:1255.
    • (1997) J. Immunol. , vol.159 , pp. 1255
    • Lu, B.1    Reichel, M.2    Fisher, D.A.3    Smith, J.F.4    Rothman, P.5
  • 30
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248.
    • (1976) Anal. Biochem. , vol.72 , pp. 248
    • Bradford, M.M.1
  • 31
    • 0025084605 scopus 로고
    • Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor
    • Fiering, S., J. P. Northrop, G. P. Nolan, P. S. Mattila, G. R. Crabtree, and L. A. Herzenberg. 1990. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes Dev. 4:1823.
    • (1990) Genes Dev. , vol.4 , pp. 1823
    • Fiering, S.1    Northrop, J.P.2    Nolan, G.P.3    Mattila, P.S.4    Crabtree, G.R.5    Herzenberg, L.A.6
  • 33
  • 35
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides, H., and N. C. Reich. 1993. Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. Science 262:1265.
    • (1993) Science , vol.262 , pp. 1265
    • Kotanides, H.1    Reich, N.C.2
  • 36
    • 0032520260 scopus 로고    scopus 로고
    • Carboxyl-truncated STAT5β is generated by a nucleus-associated serine protease in early hematopoietic progenitors
    • Meyer, J., M. Jucker, W. Ostertag, and C. Stocking. 1998. Carboxyl-truncated STAT5β is generated by a nucleus-associated serine protease in early hematopoietic progenitors. Blood 91:1901.
    • (1998) Blood , vol.91 , pp. 1901
    • Meyer, J.1    Jucker, M.2    Ostertag, W.3    Stocking, C.4
  • 37
    • 0035101634 scopus 로고    scopus 로고
    • The role of STAT6 in mast cell IL-4 production
    • Sherman, M. A. 2001. The role of STAT6 in mast cell IL-4 production. Immunol. Rev. 179:48.
    • (2001) Immunol. Rev. , vol.179 , pp. 48
    • Sherman, M.A.1
  • 38
    • 0035866398 scopus 로고    scopus 로고
    • A novel serine-dependent proteolytic activity is responsible for truncated signal transducer and activator of transcription proteins in acute myeloid leukemia blasts
    • Xia, Z., R. R. Salzler, D. P. Kunz, M. R. Baer, L. Kazim, H. Baumann, and M. Wetzler. 2001. A novel serine-dependent proteolytic activity is responsible for truncated signal transducer and activator of transcription proteins in acute myeloid leukemia blasts. Cancer Res. 61:1747.
    • (2001) Cancer Res. , vol.61 , pp. 1747
    • Xia, Z.1    Salzler, R.R.2    Kunz, D.P.3    Baer, M.R.4    Kazim, L.5    Baumann, H.6    Wetzler, M.7
  • 40
    • 0029008237 scopus 로고
    • Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element
    • Tara, D., D. L. Weiss, and M. A. Brown. 1995. Characterization of the constitutive and inducible components of a T cell IL-4 activation responsive element. J. Immunol. 154:4592.
    • (1995) J. Immunol. , vol.154 , pp. 4592
    • Tara, D.1    Weiss, D.L.2    Brown, M.A.3
  • 41
    • 0029655781 scopus 로고    scopus 로고
    • Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex
    • Weiss, D. L., J. Hural, D. Tara, L. A. Timmerman, G. Henkel, and M. A. Brown. 1996. Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex. Mol. Cell. Biol. 16:228.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 228
    • Weiss, D.L.1    Hural, J.2    Tara, D.3    Timmerman, L.A.4    Henkel, G.5    Brown, M.A.6
  • 42
    • 0033105494 scopus 로고    scopus 로고
    • NF-ATc isoforms are differentially expressed and regulated in murine T and mast cells
    • Sherman, M. A., D. R. Powell, D. L. Weiss, and M. A. Brown. 1999. NF-ATc isoforms are differentially expressed and regulated in murine T and mast cells. J. Immunol. 162:2820.
    • (1999) J. Immunol. , vol.162 , pp. 2820
    • Sherman, M.A.1    Powell, D.R.2    Weiss, D.L.3    Brown, M.A.4
  • 43
    • 0033567014 scopus 로고    scopus 로고
    • Cutting edge: IL-4 production by mast cells does not require c-maf
    • Sherman, M. A., T. Y. Nachman, and M. A. Brown. 1999. Cutting edge: IL-4 production by mast cells does not require c-maf. J. Immunol. 163:1733.
    • (1999) J. Immunol. , vol.163 , pp. 1733
    • Sherman, M.A.1    Nachman, T.Y.2    Brown, M.A.3
  • 44
    • 0034665507 scopus 로고    scopus 로고
    • An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells
    • Hural, J. A., M. Kwan, G. Henkel, M. B. Hock, and M. A. Brown. 2000. An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells. J. Immunol. 165:3239.
    • (2000) J. Immunol. , vol.165 , pp. 3239
    • Hural, J.A.1    Kwan, M.2    Henkel, G.3    Hock, M.B.4    Brown, M.A.5
  • 49
    • 0034665901 scopus 로고    scopus 로고
    • Role of common cytokine receptor γ chain (γc)- and Jak3-dependent signaling in the proliferation and survival of murine mast cells
    • Suzuki, K., H. Nakajima, N. Watanabe, S. Kagami, A. Suto, Y. Saito, T. Saito, and I. Iwamoto. 2000. Role of common cytokine receptor γ chain (γc)- and Jak3-dependent signaling in the proliferation and survival of murine mast cells. Blood 96:2172.
    • (2000) Blood , vol.96 , pp. 2172
    • Suzuki, K.1    Nakajima, H.2    Watanabe, N.3    Kagami, S.4    Suto, A.5    Saito, Y.6    Saito, T.7    Iwamoto, I.8
  • 50
    • 0034703078 scopus 로고    scopus 로고
    • Interleukin-15 induces rapid tyrosine phosphorylation of STAT6 and the expression of interleukin-4 in mouse mast cells
    • Masuda, A., T. Matsuguchi, K. Yamaki, T. Hayakawa, M. Kubo, W. J. LaRochelle, and Y. Yoshikai, 2000. Interleukin-15 induces rapid tyrosine phosphorylation of STAT6 and the expression of interleukin-4 in mouse mast cells. J. Biol. Chem. 275: 29331.
    • (2000) J. Biol. Chem. , vol.275 , pp. 29331
    • Masuda, A.1    Matsuguchi, T.2    Yamaki, K.3    Hayakawa, T.4    Kubo, M.5    LaRochelle, W.J.6    Yoshikai, Y.7
  • 51
    • 0023667058 scopus 로고
    • B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells
    • Brown, M. A., J. H. Pierce, C. J. Watson, J. Falco, J. N. Ihle, and W. E. Paul. 1987. B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells. Cell 50:809.
    • (1987) Cell , vol.50 , pp. 809
    • Brown, M.A.1    Pierce, J.H.2    Watson, C.J.3    Falco, J.4    Ihle, J.N.5    Paul, W.E.6
  • 52
    • 0034897403 scopus 로고    scopus 로고
    • Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway
    • Garren, H., P. J. Ruiz, T. A. Watkins, P. Fontoura, L. T. Nguyen, E. R. Estline, D. L. Hirschberg, and L. Steinman. 2001. Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway. Immunity 15:15.
    • (2001) Immunity , vol.15 , pp. 15
    • Garren, H.1    Ruiz, P.J.2    Watkins, T.A.3    Fontoura, P.4    Nguyen, L.T.5    Estline, E.R.6    Hirschberg, D.L.7    Steinman, L.8
  • 53
    • 0032532611 scopus 로고    scopus 로고
    • Mast cell activation and migration to lymph nodes during induction of an immune response in mice
    • Wang, H. W., N. Tedla, A. R. Lloyd, D. Wakefield, and P. H. McNeil. 1998. Mast cell activation and migration to lymph nodes during induction of an immune response in mice. J. Clin. Invest. 102:1617.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1617
    • Wang, H.W.1    Tedla, N.2    Lloyd, A.R.3    Wakefield, D.4    McNeil, P.H.5
  • 54
    • 0029790559 scopus 로고    scopus 로고
    • Requirements for interleukin-4-induced gene expression and functional characterization of Stat6
    • Mikita, T., D. Campbell, P. Wu, K. Williamson, and U. Schindler. 1996. Requirements for interleukin-4-induced gene expression and functional characterization of Stat6. Mol. Cell. Biol. 15:5811.
    • (1996) Mol. Cell. Biol. , vol.15 , pp. 5811
    • Mikita, T.1    Campbell, D.2    Wu, P.3    Williamson, K.4    Schindler, U.5
  • 55
    • 0035019227 scopus 로고    scopus 로고
    • Sulfhydryl-2 domain-containing protein tyrosine phosphatase-1 is not a negative regulator of interleukin-4 signaling in murine mast cells
    • White, E. D., R. P. Andrews, and G. K. Hershey. 2001. Sulfhydryl-2 domain-containing protein tyrosine phosphatase-1 is not a negative regulator of interleukin-4 signaling in murine mast cells. J. Leukocyte Biol. 69:825.
    • (2001) J. Leukocyte Biol. , vol.69 , pp. 825
    • White, E.D.1    Andrews, R.P.2    Hershey, G.K.3
  • 58
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • Agarwal, S., and A. Rao. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9:765.
    • (1998) Immunity , vol.9 , pp. 765
    • Agarwal, S.1    Rao, A.2
  • 59
    • 0036305450 scopus 로고    scopus 로고
    • Th cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
    • Avni, O., D. Lee, F. Macian, S. Szabo, L. Glimcher, and A. Rao. 2002. Th cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes, Nat. Immunol. 3:643.
    • (2002) Nat. Immunol. , vol.3 , pp. 643
    • Avni, O.1    Lee, D.2    Macian, F.3    Szabo, S.4    Glimcher, L.5    Rao, A.6
  • 60
    • 0034652034 scopus 로고    scopus 로고
    • IL-4 suppression of in vivo T cell activation and antibody production
    • Morris, S. C., W. C. Gause, and F. D. Finkelman. 2000. IL-4 suppression of in vivo T cell activation and antibody production, J. Immunol. 164:1734.
    • (2000) J. Immunol. , vol.164 , pp. 1734
    • Morris, S.C.1    Gause, W.C.2    Finkelman, F.D.3
  • 61
    • 0032731993 scopus 로고    scopus 로고
    • Recombinant human (rh)IL-4-mediated apoptosis and recombinant human IL-6-mediated protection of recombinant human stem cell factor-dependent human mast cells derived from cord blood mononuclear cell progenitors
    • Oskeritzian, C. A., Z. Wang. J. P. Kochan, M. Grimes, Z. Du, H. W. Chang, S. Grant, and L. B. Schwartz. 1999. Recombinant human (rh)IL-4-mediated apoptosis and recombinant human IL-6-mediated protection of recombinant human stem cell factor-dependent human mast cells derived from cord blood mononuclear cell progenitors. J. Immunol. 163:5105.
    • (1999) J. Immunol. , vol.163 , pp. 5105
    • Oskeritzian, C.A.1    Wang, Z.2    Kochan, J.P.3    Grimes, M.4    Du, Z.5    Chang, H.W.6    Grant, S.7    Schwartz, L.B.8
  • 63
    • 0030749703 scopus 로고    scopus 로고
    • Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: Stat6 is probably not required for the effect of IL-4
    • Vella, A., T. K. Teague, J. Ihle, J. Kappler, and P. Marrack. 1997. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: Stat6 is probably not required for the effect of IL-4. J. Exp. Med. 186:325.
    • (1997) J. Exp. Med. , vol.186 , pp. 325
    • Vella, A.1    Teague, T.K.2    Ihle, J.3    Kappler, J.4    Marrack, P.5
  • 64
    • 0035213428 scopus 로고    scopus 로고
    • NF-κB activation plays an important role in the IL-4-induced protection from apoptosis
    • Zamorano, J., A. L. Mora, M. Boothby, and A. D. Keegan. 2001. NF-κB activation plays an important role in the IL-4-induced protection from apoptosis. Int. Immunol. 13:1479.
    • (2001) Int. Immunol. , vol.13 , pp. 1479
    • Zamorano, J.1    Mora, A.L.2    Boothby, M.3    Keegan, A.D.4
  • 68
    • 0028294575 scopus 로고
    • Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40
    • Parry, S. L., J. Hasbold, M. Holman, and G. G. Klaus. 1994. Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J. Immunol. 152:2821.
    • (1994) J. Immunol. , vol.152 , pp. 2821
    • Parry, S.L.1    Hasbold, J.2    Holman, M.3    Klaus, G.G.4
  • 69
    • 0030444051 scopus 로고    scopus 로고
    • IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway
    • Zamorano, J., H. Y. Wang, L. M. Wang, J. H. Pierce, and A. D. Keegan. 1996. IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway. J. Immunol. 157:4926.
    • (1996) J. Immunol. , vol.157 , pp. 4926
    • Zamorano, J.1    Wang, H.Y.2    Wang, L.M.3    Pierce, J.H.4    Keegan, A.D.5
  • 70
    • 0036133110 scopus 로고    scopus 로고
    • Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis
    • Wurster, A. L., D. J. Withers, T. Uchida, M. F. White, and M. J. Grusby. 2002. Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis. Mol. Cell. Biol. 22:117.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 117
    • Wurster, A.L.1    Withers, D.J.2    Uchida, T.3    White, M.F.4    Grusby, M.J.5
  • 71
    • 0035049865 scopus 로고    scopus 로고
    • Interleukin-4 induces a switch of human intestinal must cells from proinflammatory cells to Th2-type cells
    • Bischoff, S. C., G. Sellge, M. P. Manns, and A. Lorentz. 2001. Interleukin-4 induces a switch of human intestinal must cells from proinflammatory cells to Th2-type cells. Int. Arch. Allergy Immunol. 124:151.
    • (2001) Int. Arch. Allergy Immunol. , vol.124 , pp. 151
    • Bischoff, S.C.1    Sellge, G.2    Manns, M.P.3    Lorentz, A.4
  • 72
    • 0032516816 scopus 로고    scopus 로고
    • Positive selection of apoptosis-resistant cells correlates with activation of dominant-negative STAT5
    • Bovolenta. C., L. Testolin, L. Benussi, P. M. Lievens, and E. Liboi. 1998. Positive selection of apoptosis-resistant cells correlates with activation of dominant-negative STAT5. J. Biol. Chem. 273:20779.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20779
    • Bovolenta, C.1    Testolin, L.2    Benussi, L.3    Lievens, P.M.4    Liboi, E.5


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