Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis

Biochemistry

Volumn 40, Issue 21, 2001, Pages 6335-6343

  Farazi, Thalia A ^a   Waksman, Gabriel ^a   Gordon, Jeffrey I ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; ENZYMES; NEGATIVE IONS; POLARIZATION;

SUBSTRATE RECOGNITION;

BIOCHEMISTRY;

(2 OXO)PENTADECYL COENZYME A; CARBOXYLIC ACID DERIVATIVE; COENZYME A; FUNGAL ENZYME; FUNGAL PROTEIN; GLYCINE; MYRISTOYL COENZYME A DERIVATIVE; NITROGEN; OCTAPEPTIDE; PEPTIDE; PROTEIN N MYRISTOYLTRANSFERASE; PROTEIN NMT1P; SULFUR; THIOESTER; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CELL FUNCTION; CONTROLLED STUDY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; PROTON TRANSPORT; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ACYL COENZYME A; ACYLTRANSFERASES; BINDING, COMPETITIVE; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DIPEPTIDES; ENZYME INHIBITORS; IMIDAZOLES; MACROMOLECULAR SUBSTANCES; OLIGOPEPTIDES; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 0035967517     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0101401     Document Type: Article

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