Dietary restriction initiated late in life can reduce mitochondrial protein carbonyls in rat livers: Western blot studies

Biogerontology

Volumn 1, Issue 4, 2000, Pages 321-328

  Nagai, Michiko ^a   Takahashi, Ryoya ^a   Goto, Sataro ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

Aging; ATPase; Dietary restriction; Mitochondria; Oxidative stress; Protein carbonyl; Succinyl CoA synthetase; Western blot

Indexed keywords

PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SUCCINYL COENZYME A SYNTHETASE;

AGING; ANIMAL; ARTICLE; FISCHER 344 RAT; FOOD DEPRIVATION; LIVER; LIVER MITOCHONDRION; MALE; METABOLISM; METHODOLOGY; OXIDATION REDUCTION REACTION; PHYSIOLOGY; RAT; WESTERN BLOTTING;

AGING; ANIMALS; BLOTTING, WESTERN; FOOD DEPRIVATION; LIVER; MALE; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; PROTEINS; PROTON-TRANSLOCATING ATPASES; RATS; RATS, INBRED F344; SUCCINATE-COA LIGASES;

EID: 0034578393     PISSN: 13895729     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Aloso E and Rubo V (1995) Affinity cleavage of carbamoyl-phosphate synthetase β localizes regions of the enzyme interacting with the molecule of ATP that phosphorylates carbamate. Eur J Biochem 229: 377-384
2. Aloso E, Cervera J, Garcia-Espana A, Bendala E and Rubio V (1992) Oxidative inactivation of carvamoyl phosphate synthetase (ammonia) Mechanism and sites of oxidation, degradation of the oxidized enzyme, and inactivation by glycerol, EDTA, and thiol protecting agents. J Biol Chem 267: 4524-4532
3. Ames BN, Shigenaga MK and Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 90: 7915-7922
4. Beckman KB and Ames BN (1998) The free radical theory of aging matures. Physiol Rev 78: 547-581
5. Barogi S, Baracca A, Parenti CG, Bovina C, Formiggini G, Marchetti M, Solaini G and Lenaz G (1995) Lack of major changes in ATPase activity in mitochondria from liver, heart, and skeletal muscle of rats upon ageing. Mech Ageing Dev 84: 139-150
6. Cao G and Cutler RG (1995) Protein oxidation and aging. I. Difficulties in measuring reactive protein carbonyls in tissue using 2,4-dinitrophenylhydrazine. Arch Biochem Biophys 320: 106-114
7. Chance B, Sies H and Boveris A. (1979) Hydroperoxide metabolism in mammalian organs. Physiol Rev 59: 527-605
8. Chen JJ and Yu BP (1994) Alterations in mitochondrial membrane fluidity by lipid peroxidation products. Free Radic Biol Med 17: 411-418
9. Clark S (1976) A major polypeptide component of rat liver mitochondria: Carbamyl phosphate synthetase. J Biol Chem 251: 950-961
10. Goodell SC and Cortopassi GA (1998) Analysis of oxygen consumption and mitochondrial permeability with age in mice. Mech Ageing Dev 101: 245-256
11. Goto S and Nakamura A (1997) Age-associated, oxidatively modified proteins: A critical evaluation. Age 20: 81-89
12. Hagen TM, Yowe DL, Bartholomew JC, Wehr CM, Do KL, Park JY and Ames BN (1997) Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA 94: 3064-3069
13. Halliwell B and Gutteridge JM (1986) Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. Arch Biochem Biophys 246: 501-514
14. Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 2: 289-300
15. Ishigami A and Goto S (1990) Effect of dietary restriction on the degradation of proteins in senescent mouse liver parenchymal cells in culture. Arch Biochem Biophys 283: 362-366
16. Johnson D and Lardy H (1967) Isolation of liver and kidney mitochondria. Methods Enzymol 10: 94-96
17. Kaneko T, Tahara S and Matsuo M (1996) Nonlinear accumulation of 8-hydroxy-2-deoxyguanosine, a marker of DNA damage, during aging. Mutation Res 316: 277-285
18. Kaneko T, Tahara S and Matsuo M (1997) Retarding effect of dietary restriction on the accumulation of 8-hydroxy-2-deoxyguanosine in organs o Fischer 344 rats during aging. Free Radie Biol Med 23: 76-81
19. Laganiere S and Yu BP (1994) Effect of chronic food restriction in aging rats. I. Liver subcellular membranes. Mech Ageing Dev 48: 207-219
20. Lass A, Sohal BH, Weindruch R, Forster MJ and Sohal RS (1998) Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic Biol Med 25: 1089-1097
21. Lee J, Yu BP and Herlihy JT (1999) Modulation of cardiac mitochondrial membrane fluidity by age and calorie intake. Free Radie Biol Med 26: 260-265
22. Lenaz G (1998) Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta 1366: 53-67
23. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shaltiel S and Stadtman ER (1990) Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 186: 464-478
24. Linnane AW, Maruzuki S, Ozawa T and Tanaka M (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet i: 642-645
25. Martin GM, Austad SN and Johnson TE (1996) Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nature Genetics 13: 25-34
26. Martinez M, Hernandez AI, Martinez N and Ferrandiz ML (1996) Age-related increase in oxidized proteins in mouse synaptic mitochondria. Brain Res 731: 246-248
27. Masoro EJ (1995) Design Issue in the use of the diet-restricted rodent model. In: Hart RW et al. (eds) Dietary Restriction, pp 41-50. ILSI Press, Washington
28. Nakamura A and Goto S (1996) Analysis of protein carbonyls with 2,4-dinitrophenyl hydrazine and its antibodies by immunoblot in two-dimensional gel electrophoresis. J Biochem 119: 768-774
29. Sastre J, Pallardó FV, Plá R, Pell A, Juan G, O'Connor JE, Estrela JM, Miquel J and Vi J (1996) Aging of the liver: age-associated mitochondrial damage in intact hepatocytes. Hepatology 24: 1199-1205
30. Shigenaga MK, Hagen TM and Ames BN (1994) Oxidative damage and mitochodrial decay in aging. Proc Natl Acad Sci USA 91: 10771-10778
31. Sohal RS and Dubey A (1994) Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic Biol Med 16: 621-626
32. Sohal RS, Sohal BH and Orr WC (1995) Mitochondnal superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. Free Radic Biol Med 19: 499-504
33. Sokal RR and Rohlf FJ (1981) Biometry, 2nd ed. WA Freeman, New York
34. Stadtman ER (1992) Protein oxidation and aging. Science 257: 1220-1224
35. Starke-Reed PE and Oliver CN (1989) Protein oxidation and proteolysis during aging and oxidative stress. Arch Biochem Biophys 275: 559-567
36. Takahashi R and Goto S (1987) Influence of dietary restriction on accumulation of heat-labile enzyme molecules in the liver and brain of mice. Arch Biochem Biophys 257: 200-206
37. Tauchi H and Sato T (1968) Age changes in size and number of mitochondria of human hepatic cells. J Gerontol 23: 454-461
38. Weindruch R and Walford RL (1982) Dietary restriction in mice beginning at 1 year of age: Effect on life-span and spontaneous cancer incidence. Science, 215: 1415-1418
39. Wilson PD and Franks LM (1975) The effect of age on mitochondrial ultrastructure and enzymes. Adv Exp Med Biol 53: 171-183
40. Yan L-J, Levine RL and Sohal RS (1997) Oxidative damage during aging targets mitochondrial aconitase. Proc Natl Acad Sci USA 94: 11168-11172
41. Yu BP, Chen JJ, Kang CM, Choe M, Maeng, YS and Kristal BS (1996) Mitochondrial aging and lipoperoxidative products. In: Kitani K, Aoba A and Goto S (eds) Pharmacological Intervention in Aging and Age-associated Disorders. Ann NY Acad Sci Vol 786, 44-56. The New York Academy of Sciences, New York