Can pretreatment screening for dhps and dhfr point mutations in Plasmodium falciparum infections be used to predict sulfadoxine-pyrimethamine treatment failure?

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 95, Issue 3, 2001, Pages 315-319

  Omar, S A ^a,b   Adagu, I S ^b   Warhurst, D C ^b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

dhfr; dhps; Kenya; Plasmodium falciparum; Point mutations; Sulfadoxine pyrimethamine failure

Indexed keywords

ANTIMALARIAL AGENT; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FANSIDAR; MEROZOITE SURFACE PROTEIN 2, PLASMODIUM; PARASITE ANTIGEN; PROTOZOAL PROTEIN; PYRIMETHAMINE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; DRUG COMBINATION; FEMALE; GENE; GENETIC SCREENING; GENETICS; HUMAN; INFANT; MALARIA FALCIPARUM; MALE; METHODOLOGY; POINT MUTATION; PRESCHOOL CHILD; TREATMENT FAILURE;

ADOLESCENT; ADULT; ANTIGENS, PROTOZOAN; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; DIHYDROPTEROATE SYNTHASE; DRUG COMBINATIONS; FEMALE; GENES, PROTOZOAN; GENETIC SCREENING; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; POINT MUTATION; PROTOZOAN PROTEINS; PYRIMETHAMINE; SULFADOXINE; TETRAHYDROFOLATE DEHYDROGENASE; TREATMENT FAILURE;

EID: 0035350481     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(01)90250-0     Document Type: Article

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