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Volumn 3, Issue 5, 2002, Pages 679-686

The hunt for new genes and polymorphisms that can control the response to drugs

Author keywords

Association study; Case control; CYP450; Microarray; Pharmacogenetics; Pharmacogenomics; Polymorphism; TDT

Indexed keywords

CYCLOSPORIN A; CYTOCHROME P450; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; DRUG METABOLIZING ENZYME; ESTROGEN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TACROLIMUS;

EID: 0036740844     PISSN: 14622416     EISSN: None     Source Type: Journal    
DOI: 10.1517/14622416.3.5.679     Document Type: Article
Times cited : (6)

References (44)
  • 1
    • 0034621009 scopus 로고    scopus 로고
    • Science, medicine and the future: Pharmacogenetics
    • Wolf CR, Smith G, Smith RL: Science, medicine and the future: pharmacogenetics. Br. Med. J. 320, 987-990 (2000).
    • (2000) Br. Med. J , vol.320 , pp. 987-990
    • Wolf, C.R.1    Smith, G.2    Smith, R.L.3
  • 2
    • 0034660560 scopus 로고    scopus 로고
    • Pharmacogenetics and the practice of medicine
    • Roses AD: Pharmacogenetics and the practice of medicine. Nature 405, 857-865 (2000).
    • (2000) Nature , vol.405 , pp. 857-865
    • Roses, A.D.1
  • 3
    • 0035669996 scopus 로고    scopus 로고
    • Strategies to find new genes involved in drug metabolism
    • Sheffield LJ: Strategies to find new genes involved in drug metabolism. Curr Opin. Mol. Ther. 3, 579-584 (2001).
    • (2001) Curr. Opin. Mol. Ther , vol.3 , pp. 579-584
    • Sheffield, L.J.1
  • 4
    • 0036209142 scopus 로고    scopus 로고
    • Candidate gene approach for pharmacogenetic studies
    • Ring HZ, Kroetz DL: Candidate gene approach for pharmacogenetic studies. Pharmacogenomics 3, 47-56 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 47-56
    • Ring, H.Z.1    Kroetz, D.L.2
  • 5
    • 0036119167 scopus 로고    scopus 로고
    • The role of pharmacogenetically-variable cytochrome P450 enzymes in drug abuse and dependence
    • Howard LA, Sellers EM, Tyndale RF: The role of pharmacogenetically-variable cytochrome P450 enzymes in drug abuse and dependence. Pharmacogenomics 3, 185-199 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 185-199
    • Howard, L.A.1    Sellers, E.M.2    Tyndale, R.F.3
  • 6
    • 0035474758 scopus 로고    scopus 로고
    • Pharmacogenetics
    • Roses AD: Pharmacogenetics. Hum. Mol. Genet. 10, 2261-2267 (2001).
    • (2001) Hum. Mol. Genet , vol.10 , pp. 2261-2267
    • Roses, A.D.1
  • 7
    • 0036124149 scopus 로고    scopus 로고
    • The application of genetics to the discovery of better medicines
    • Pettipher R, Cardon LR: The application of genetics to the discovery of better medicines. Pharmacogenomics 3, 257-263 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 257-263
    • Pettipher, R.1    Cardon, L.R.2
  • 8
    • 0032748555 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist?
    • Nebert DW. Pharmacogenetics and pharmacogenomics: why is this relevant to the clinical geneticist? Clin. Gen. 56, 247-258 (1999).
    • (1999) Clin. Gen , vol.56 , pp. 247-258
    • Nebert, D.W.1
  • 10
    • 0037192320 scopus 로고    scopus 로고
    • Toxicology and genetic toxicology in the new era of 'toxicogenomics': Impact of '-omics' technologies
    • Aardema MJ, MacGregor JT: Toxicology and genetic toxicology in the new era of 'toxicogenomics': impact of '-omics' technologies. Mutat. Res. 499, 13-25 (2002).
    • (2002) Mutat. Res , vol.499 , pp. 13-25
    • Aardema, M.J.1    MacGregor, J.T.2
  • 11
    • 0026240125 scopus 로고
    • Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylatrion (cytochrome P4502D6) phenotypes
    • Daly AK, Armstrong M, Monkman SC, Idle ME, Idle JR: Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylatrion (cytochrome P4502D6) phenotypes. Pharmacogenetics 1, 33-41 (1991).
    • (1991) Pharmacogenetics , vol.1 , pp. 33-41
    • Daly, A.K.1    Armstrong, M.2    Monkman, S.C.3    Idle, M.E.4    Idle, J.R.5
  • 12
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachs C, Brockmoller J, Bauer S, Roots I: Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am. J. Hum. Genet. 60, 284-295 (1997).
    • (1997) Am. J. Hum. Genet , vol.60 , pp. 284-295
    • Sachs, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 13
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD: CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3, 229-243 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 14
    • 0034139510 scopus 로고    scopus 로고
    • The use of single nucleotide polymorphisms in the isolation of common disease genes
    • Riley JH, Allan CJ, Lai E, Roses A: The use of single nucleotide polymorphisms in the isolation of common disease genes. Pharmacogenomics 1, 39-47 (2000).
    • (2000) Pharmacogenomics , vol.1 , pp. 39-47
    • Riley, J.H.1    Allan, C.J.2    Lai, E.3    Roses, A.4
  • 15
    • 0034022213 scopus 로고    scopus 로고
    • The use of single-nucleotide polymorphism maps in pharmacogenomics
    • McCarthy JJ, Hilfiker R: The use of single-nucleotide polymorphism maps in pharmacogenomics. Nat. Biotechnol. 18, 505-508 (2000).
    • (2000) Nat. Biotechnol , vol.18 , pp. 505-508
    • McCarthy, J.J.1    Hilfiker, R.2
  • 16
    • 0035750366 scopus 로고    scopus 로고
    • Recent advances in P450 research
    • Raucy JL, Allen SW: Recent advances in P450 research. Pharmacogenomics J. 1, 178-186 (2001).
    • (2001) Pharmacogenomics J , vol.1 , pp. 178-186
    • Raucy, J.L.1    Allen, S.W.2
  • 18
    • 0023879378 scopus 로고
    • Human cytochrome P450 PB-1: A multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10
    • Meehan RR Gosden JR, Rout D et al.: Human cytochrome P450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10. Am. J. Hum. Genet. 42, 26-37 (1988).
    • (1988) Am. J. Hum. Genet , vol.42 , pp. 26-37
    • Meehan, R.R.1    Gosden, J.R.2    Rout, D.3
  • 19
    • 0023954396 scopus 로고
    • Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22
    • Gonzalez FJ, Vilbois F, Hardwick JP et al.: Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22. Genomics 2, 174-179 (1988).
    • (1988) Genomics , vol.2 , pp. 174-179
    • Gonzalez, F.J.1    Vilbois, F.2    Hardwick, J.P.3
  • 20
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch NJ: Searching for genetic determinants in the new millennium. Nature 405, 847-856 (2000).
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 21
    • 0035513076 scopus 로고    scopus 로고
    • Candidate gene case-control association studies: Advantages and potential pitfalls
    • Daly AK, Day CP: Candidate gene case-control association studies: advantages and potential pitfalls. Br. J. Clin. Pharmacol. 52, 489-499 (2001).
    • (2001) Br. J. Clin. Pharmacol , vol.52 , pp. 489-499
    • Daly, A.K.1    Day, C.P.2
  • 24
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K: The future of genetic studies of complex human diseases. Science 273, 1516-1517 (1996).
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 25
    • 0035752835 scopus 로고    scopus 로고
    • Pharmacogenomics, ethnicity and susceptibility genes
    • Nebert DW, Menon AG: Pharmacogenomics, ethnicity and susceptibility genes. Pharmacogenomics J. 1, 19-22 (2001).
    • (2001) Pharmacogenomics J , vol.1 , pp. 19-22
    • Nebert, D.W.1    Menon, A.G.2
  • 26
    • 0032542897 scopus 로고    scopus 로고
    • What's wrong with Bonferroni adjustments?
    • Perneger TV: What's wrong with Bonferroni adjustments? Br. Med. J. 316, 1236-1238 (1998).
    • (1998) Br. Med. J , vol.316 , pp. 1236-1238
    • Perneger, T.V.1
  • 27
    • 0033812655 scopus 로고    scopus 로고
    • Genetic association studies of bronchial asthma-a need for Bonferroni correction?
    • Boehringer S, Epplen JT, Krawczak M: Genetic association studies of bronchial asthma-a need for Bonferroni correction? Hum. Genet. 107, 197 (2000).
    • (2000) Hum. Genet , vol.107 , pp. 197
    • Boehringer, S.1    Epplen, J.T.2    Krawczak, M.3
  • 28
    • 0032427048 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling
    • Risch N, Teng J: The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Res. 8, 1273-1288 (1998).
    • (1998) Genome Res , vol.8 , pp. 1273-1288
    • Risch, N.1    Teng, J.2
  • 29
    • 4243401846 scopus 로고    scopus 로고
    • MR genetic dissection of complex traits in a high density SNP map era
    • Davarsi A: MR genetic dissection of complex traits in a high density SNP map era. Am. J. Hum. Genet. 63(Suppl.), A229 (1999).
    • (1999) Am. J. Hum. Genet , vol.63 , Issue.SUPPL.
    • Davarsi, A.1
  • 30
    • 0032897131 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping
    • Teng J, Risch N: The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping. Genome Res. 9, 234-241 (1999).
    • (1999) Genome Res , vol.9 , pp. 234-241
    • Teng, J.1    Risch, N.2
  • 31
    • 18544386662 scopus 로고    scopus 로고
    • Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity
    • Hosking LK, Boyd PR, Xu CF et al.: Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity. Pharmacogenomics J. 2, 165-175 (2002).
    • (2002) Pharmacogenomics J , vol.2 , pp. 165-175
    • Hosking, L.K.1    Boyd, P.R.2    Xu, C.F.3
  • 32
    • 0035656115 scopus 로고    scopus 로고
    • Invited review: Pharmacogenetics of oestrogen replacement therapy
    • Herrington DM, Klein KP: Invited review: pharmacogenetics of oestrogen replacement therapy. J. Appl. Physiol. 91, 2776-2784 (2001).
    • (2001) J. Appl. Physiol , vol.91 , pp. 2776-2784
    • Herrington, D.M.1    Klein, K.P.2
  • 33
    • 0035752337 scopus 로고    scopus 로고
    • Genes that cocluster with oestrogen receptor alpha in microarray analysis of breast biopsies
    • Dressman MA, Walz TM, Lavedan C et al.: Genes that cocluster with oestrogen receptor alpha in microarray analysis of breast biopsies. Pharmacogenomics J. 1, 135-141 (2001).
    • (2001) Pharmacogenomics J , vol.1 , pp. 135-141
    • Dressman, M.A.1    Walz, T.M.2    Lavedan, C.3
  • 34
    • 0031730097 scopus 로고    scopus 로고
    • Drug target validation and identification of secondary drug target effects using DNA microarrays
    • Marton MJ, DeRisi JL, Bennett HA et al.: Drug target validation and identification of secondary drug target effects using DNA microarrays. Nat. Med. 4, 1293-1301 (1998).
    • (1998) Nat. Med , vol.4 , pp. 1293-1301
    • Marton, M.J.1    DeRisi, J.L.2    Bennett, H.A.3
  • 35
    • 0036233675 scopus 로고    scopus 로고
    • Developmental therapeutics programme at the NCI: Molecular target and drug discovery process
    • Monga M, Sausville EA: Developmental therapeutics programme at the NCI: molecular target and drug discovery process. Leukaemia 16, 520-526 (2002).
    • (2002) Leukaemia , vol.16 , pp. 520-526
    • Monga, M.1    Sausville, E.A.2
  • 36
    • 0033966933 scopus 로고    scopus 로고
    • High-throughput gene expression analysis for drug discovery
    • Lennon GG: High-throughput gene expression analysis for drug discovery. Drug Discov. Today 5, 59-66 (2000).
    • (2000) Drug Discov. Today , vol.5 , pp. 59-66
    • Lennon, G.G.1
  • 37
    • 0036262111 scopus 로고    scopus 로고
    • Analyzing array data using supervised methods
    • Ringner M, Peterson C, Khan J: Analyzing array data using supervised methods. Pharmacogenomics 3, 403 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 403
    • Ringner, M.1    Peterson, C.2    Khan, J.3
  • 38
    • 0034252557 scopus 로고    scopus 로고
    • Applications of biochip and microarray systems in pharmacogenomics
    • Jain KK: Applications of biochip and microarray systems in pharmacogenomics. Pharmacogenomics 1, 289-307 (2000).
    • (2000) Pharmacogenomics , vol.1 , pp. 289-307
    • Jain, K.K.1
  • 39
    • 0033552437 scopus 로고    scopus 로고
    • How DNA microarrays and expression profiling will affect clinical practice
    • Friend SH: How DNA microarrays and expression profiling will affect clinical practice. Br. Med. J. 319, 1306-1307 (1999).
    • (1999) Br. Med. J , vol.319 , pp. 1306-1307
    • Friend, S.H.1
  • 40
    • 0032555671 scopus 로고    scopus 로고
    • Direct allelic variation scanning of the yeast genome
    • Winzeler EA Richards DR, Conway AR et al: Direct allelic variation scanning of the yeast genome. Science 281, 1194-1197 (1998).
    • (1998) Science , vol.281 , pp. 1194-1197
    • Winzeler, E.A.1    Richards, D.R.2    Conway, A.R.3
  • 41
    • 0032402905 scopus 로고    scopus 로고
    • The integration of microarray information in the drug development process
    • Braxton S, Bedilion T: The integration of microarray information in the drug development process. Curr. Opin. Biotechnol. 9, 643-649 (1998).
    • (1998) Curr. Opin. Biotechnol , vol.9 , pp. 643-649
    • Braxton, S.1    Bedilion, T.2
  • 42
    • 0032403973 scopus 로고    scopus 로고
    • Linkage disequilibrium mapping of complex disease: Fantasy or reality?
    • Terwilliger JD, Weiss KM: Linkage disequilibrium mapping of complex disease: fantasy or reality? Curr. Opin. Biotechnol. 9, 578-594 (1998).
    • (1998) Curr. Opin. Biotechnol , vol.9 , pp. 578-594
    • Terwilliger, J.D.1    Weiss, K.M.2
  • 43
    • 0033039497 scopus 로고    scopus 로고
    • Prospects for whole-genome linkage disequilibrium, mapping of common disease genes
    • Kruglyak L: Prospects for whole-genome linkage disequilibrium, mapping of common disease genes. Nat. Genet. 22, 139-144 (1999).
    • (1999) Nat. Genet , vol.22 , pp. 139-144
    • Kruglyak, L.1
  • 44
    • 0034139799 scopus 로고    scopus 로고
    • The predictive power of haplotypes in clinical response
    • Judson R, Stephens JC, Windemuth A: The predictive power of haplotypes in clinical response. Pharmacogenomics 1, 15-26 (2000).
    • (2000) Pharmacogenomics , vol.1 , pp. 15-26
    • Judson, R.1    Stephens, J.C.2    Windemuth, A.3


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