Functional dissection of the Drosophila modifier of variegation Su(var)3-7

Development

Volumn 129, Issue 17, 2002, Pages 3975-3982

  Jaquet, Yannis ^a   Delattre, Marion ^a   Spierer, Anne ^a   Spierer, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Drosophila melanogaster; Heterochromatin; Position effect variegation

Indexed keywords

CHROMOSOME PROTEIN; DNA BINDING PROTEIN; ZINC FINGER PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMOSOME BAND; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EUCHROMATIN; FEMALE; GENE MAPPING; GENE SILENCING; HETEROCHROMATIN; INHIBITION KINETICS; MALE; NONHUMAN; POSITION EFFECT VARIEGATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; WILD TYPE;

ANIMALS; CHROMOSOMES; CLONING, MOLECULAR; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EUCHROMATIN; FEMALE; GENE SILENCING; HETEROCHROMATIN; MALE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0036712086     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31
2. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
3. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
4. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer
5. The Drosophila stonewall gene encodes a putative transcription factor essential for germ cell development
6. Position-effect variegation in Drosophila: The modifier Su(var)3-7 is a modular DNA-binding protein
7. SU(VAR)3-7, a Drosophila heterochromatin-associated protein and companion of HP1 in the genomic silencing of position-effect variegation
8. The modifier of position-effect variegation Suvar(3)7 of Drosophila: There are two alternative transcripts and seven scattered zinc fingers, each preceded by a tryptophan box
9. Dimerisation of a chromo shadow domain and distinctions from the chromodomain as revealed by structural analysis
10. The genomic silencing of position-effect variegation in Drosophila melanogaster: Interaction between the heterochromatin-associated proteins Su(var)3-7 and HP1
11. The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation
12. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster
13. The heterochromatin protein 1 prevents telomere fusions in Drosophila
14. A novel genetic system to detect protein-protein interactions
15. The scs' boundary element: Characterization of boundary element-associated factors
16. Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3
17. Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila
18. Mammalian chromodomain proteins: Their role in genome organisation and expression
19. Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos
20. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
21. A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors
22. Heterochromatin formation in mammalian cells: Interaction between histones and HP1 proteins
23. Functional analysis of the chromo domain of HP1
24. Regulation of chromatin structure by site-specific historic H3 methyltransferases
25. Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-finger protein
26. Position effect variegation and chromatin proteins
27. Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity
28. Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing
29. A GAL4-HP1 fusion protein targeted near heterochromatin promotes gene silencing
30. The enhancer-blocking suppressor of Hairy-wing zinc finger protein of Drosophila melanogaster alters DNA structure
31. Chromatin insulator elements block the silencing of a target gene by the Drosophila polycomb response element (PRE) but allow trans interactions between PREs on different chromosomes
32. A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants
33. The hinge and chromo shadow domain impart distinct targeting of HP1 - Like proteins
34. Position-effect variegation in Drosophila
35. The fourth chromosome of Drosophila melanogaster: Interspersed euchromatic and heterochromatic domains
36. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes
37. Unfolding the mysteries of heterochromatin
38. Heterochromatin and gene expression in Drosophila
39. A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin
40. Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR
41. Visualization of chromosomal domains with boundary element-associated factor BEAF-32