Study of the gonocyte cell cycle in irradiated TP53 knockout mouse foetuses and newborns

International Journal of Radiation Biology

Volumn 78, Issue 8, 2002, Pages 703-709

  Moreno, S G ^a   Dutrillaux, B ^a   Coffigny, H ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FETUS; GAMMA IRRADIATION; GERM CELL; KNOCKOUT MOUSE; MALE; MITOSIS INHIBITION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; RADIOSENSITIVITY; STAINING;

ANIMALS; ANIMALS, NEWBORN; BROMODEOXYURIDINE; CELL CYCLE; FETUS; GENES, P53; GENOTYPE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOSIS; POLYMERASE CHAIN REACTION; RADIATION TOLERANCE; RATS; TIME FACTORS;

ANIMALIA; RODENTIA;

EID: 0036687919     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000210134818     Document Type: Article

References (32)

1. P53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
2. Changes in the radiosensitivity of the testis during foetal development
3. Regulatory role of p27kip1 in the mouse and human testis
4. The role of the minor suppressor p53 in spermatogenesis
5. Effect of dose-rate (γ-irradiation) on the mitotically-active and differentiating germ cell of the prenatal male rat
6. Comparative analysis of p73 and p53 regulation and effector functions
7. Radiosensitivity of male germ cells in neonatal rats
8. Continuous and acute irradiation effects on developing animals
9. p73 is a simian [correction of human] p53-related protein that can induce apoptosis
10. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
11. Promoter specificity and stability control of the p53-related protein p73
12. Structure, function and regulation of p63 and p73
13. The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
14. Radiation sensitivity of the human testis
15. Status of p53, p21, mdm2, pRb proteins and DNA methylation in gonocytes of control and γ-irradiated rats during testicular development
16. DNA damage and p53-mediated cell cycle arrest: A reevaluation
17. Influence of germ cells upon Sertoli cells during continuous low-dose-rate γ-irradiation of adult rats
18. An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis
19. p53 controls low DNA damage-dependent premeiotic checkpoint and facilitates DNA repair during spermatogenesis
20. The physiology of p16(INK4A)-mediated G1 proliferative arrest
21. CDK inhibitors: Positive and negative regulators of G1-phase progression
22. Expression of p53 in normal and γ-irradiated rat testis suggests a role for p53 in meiotic recombination and repair
23. The effect of cysteamine on the survival of fetal germ cells after irradiation
24. Evidence for a second cell cycle block at G2/M by p53
25. Response to fission neutron irradiation of spermatogonial stem cells in different stages of the cycle of the seminiferous epithelium
26. The sensitivity of quiescent and proliferating mouse spermatogonial stem cells to X-irradiation
27. Radiosensitivity of testicular cells in the fetal mouse
28. Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice
29. p53-independent functions of the p19(ARF) tumor suppressor
30. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
31. MDM2 suppresses p73 function without promoting p73 degradation
32. The potential tumor suppressor p73 differentially regulates cellular p53 target genes