Expression and regulation of the AMP-activated protein kinase-SNF1 (sucrose non-fermenting 1) kinase complexes in yeast and mammalian cells: Studies using chimaeric catalytic subunits

Biochemical Journal

Volumn 365, Issue 3, 2002, Pages 629-638

  Daniel, Tyrone ^a   Carling, David ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Glucose repression; Metabolic stress; Protein phosphorylation

Indexed keywords

ADENOSINETRIPHOSPHATE; CELLS; CHEMICAL ACTIVATION; GLUCOSE; MUTAGENS; YEAST;

ENERGY HOMOEOSTASIS;

ENZYMES;

ADENOSINE PHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE; SNF1 PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; ENZYME REPRESSION; ENZYME SUBUNIT; GENETIC CONSERVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; CATALYTIC DOMAIN; CELL LINE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; MACROMOLECULAR SUBSTANCES; PLASMIDS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES; ZINC FINGERS;

ANIMALIA; MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0036683346     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020124     Document Type: Article

References (46)

1. The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
2. The AMP-activated protein kinase: Fuel gauge of the mammalian cell
3. AMP-activated protein kinase: An ultrasensitive system for monitorin cellular energy charge
4. 2+/calmodulin activates the calmodulin-dependent protein kinase-I cascade, via 3 independent mechanisms
5. Yeast Snf1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo
6. Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP/ATP ratio
7. Yeast carbon catabolite repression
8. Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase
9. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
10. AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes
11. The AMP-activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex
12. Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
13. Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
14. Cloning and genetic mapping of SNF1, a gene required for expression of glucose-repressible genes in Saccharomyces cerevisiae
15. A yeast gene that is essential for release from glucose repression encodes a protein kinase
16. The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1
17. Snf1 protein kinase regulates phosphorylation of the Mig1 repressor in Saccharomyces cerevisiae
18. Regulated nuclear translocation of the Mig1 glucose repressor
19. Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway
20. Glucose repression affects ion homeostasis in yeast through the regulation of the stress-activated ENA1 gene
21. Mammalian AMP-activated protein-kinase subfamily
22. AMP-activated protein kinase isoenzyme family: Subunit structure and chromosomal location
23. Identification of a novel AMP-activated protein kinase β isoform which is highly expressed in skeletal muscle
24. Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding
25. Glucose regulates protein interactions within the SNF1 protein kinase complex
26. The Snf1 protein kinase and its activating subunit. Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex
27. Subcellular localization of the Snf1 kinase is regulated by specific β subunits and a novel glucose signalling mechanism
28. Regulation of AMP-activated protein kinase activity by the noncatalytic β and γ subunits
29. Functional domains of the α1 catalytic subunit of the AMP-activated protein kinase
30. High efficiency transformation of mammalian cells by plasmid DNA
31. Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure
32. Characterization of AMP-activated protein kinase β subunit and γ subunit. Assembly of the heterotrimeric complex in vitro
33. Tissue distribution of AMP-activated protein kinase, and lack of activation by cyclic AMP-dependent protein kinase, studied using a specific and sensitive peptide assay
34. Characterisation of the AMP-activated protein kinase kinase from rat liver and identification of threonine-172 as the major site at which it phosphorylates AMP-activated protein kinase
35. The regulation of AMP-activated protein kinase by phosphorylation
36. A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle
37. Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism
38. Repression by SSN6-TUP1 is directed by MIGI, a repressor/activator protein
39. Regulation of Snf1 kinase
40. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
41. Dealing with energy demand: The AMP-activated protein kinase
42. Phosphorylation and inactivation of HMG-CoA reductase at the AMP-activated protein kinase site in response to fructose treatment of isolated hepatocytes
43. Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase
44. Feasting, fasting and fermenting: Glucose sensing in yeast and other cells
45. The α1 and α2 isoforms of the AMP-activated protein kinase have similar activities in rat liver, but exhibit differences in substrate specificity in vitro
46. A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex