CCR5 and CXCR4 expression after highly active antiretroviral therapy (HAART) [2]

Journal of Acquired Immune Deficiency Syndromes

Volumn 30, Issue 4, 2002, Pages 458-460

  Smith, Kimberly Y ^a   Kumar, Sampath ^a   Pulvirenti, Joseph J ^a   Gianesin, MaryAnn ^a   Kessler, Harold A ^a   Landay, Alan ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; VIRUS RNA;

CELL COUNT; DRUG EFFECT; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TREATMENT OUTCOME; VIRUS LOAD; VIRUS REPLICATION; VIRUS TRANSMISSION;

EID: 0036682593     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-200208010-00013     Document Type: Letter

References (12)

1. Identification of a Major Coreceptor for Primary Isolates of HIV-1
2. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated in human T lymphocytes
3. CCR5 levels and expression pattern correlate with infectability of macrophage-tropic HIV-1, in vitro
4. Heterozygosity for a deletion in CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals
5. Expression of chemokine receptors CXCR4 and CCR5 in HIV-1-infected and uninfected individuals
6. CCR5 and CXCR4 chemokine receptor expression and β-chemokine production during early T-cell repopulation induced by highly active antiretroviral therapy
7. CCR5 and CXCR4 Expression on memory and naive T cells in HIV-1 infection and response to highly active antiretroviral therapy
8. CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1
9. CC chemokine receptor 5 cell surface expression in relation to CC chemokine receptor 5 genotype and the clinical course of HIV-1 infection
10. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
11. Adaptations to promiscuous usage of CC and CXC-chemokine coreceptors in vivo correlates with HIV-1 disease progression
12. Regulation of CCR5 and CXCR4 expression by type 1 and type 2 cytokines: CCR5 expression is downregulated by IL-10 in CD4-positive lymphocytes