How Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing

RNA

Volumn 8, Issue 8, 2002, Pages 1068-1077

  James, Shelly Ann ^a   Turner, William ^a   Schwer, Beate ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Prp22; Prp43; Spliceosome; Zinc knuckle

Indexed keywords

ARTICLE; CATALYSIS; CELL GROWTH; CONFORMATIONAL TRANSITION; GENE MUTATION; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RNA SPLICING; SPLICEOSOME; TEMPERATURE SENSITIVE MUTANT; TRANSESTERIFICATION; YEAST;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; DEAD-BOX RNA HELICASES; FUNGAL PROTEINS; GENES, FUNGAL; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA HELICASES; RNA PRECURSORS; RNA SPLICING; RNA, FUNGAL; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; SPLICEOSOMES;

EID: 0036674909     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202022033     Document Type: Article

References (36)

1. NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition
2. SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing
3. Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA
4. Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae
5. Requirement for SLU7 in yeast pre-mRNA splicing is dictated by the distance between the branchpoint and the 3′ splice site
6. Splicing of precursors to mRNA by the spliceosome
7. The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers
8. Characterization and cloning of the human splicing factor 9G8: A novel 35 kDa factor of the serine/arginine protein family
9. Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing
10. Specific binding of HIV-1 nucleocapsid protein to PSI RNA in vitro requires N-terminal zinc finger and flanking basic amino acid residues
11. An essential splicing factor, SLU7, mediates 3' splice site choice in yeast
12. Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing
13. A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae
14. Stages in the second reaction of pre-mRNA splicing: The final step is ATP independent
15. Characterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast
16. Analysis of the splicing machinery in fission yeast: A comparison with budding yeast and mammals
17. Structural basis for recognition of the intron branch site RNA by splicing factor 1
18. Dynamic RNA-RNA interactions in the spliceosome
19. Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome
20. Splicing of precursors to mRNA by the spliceosome
21. The role of U5 snRNP in pre-mRNA splicing
22. RNA-RNA interactions in the spliceosome: Unraveling the ties that bind
23. Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1
24. Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing
25. Characterization of dominant-negative mutants of the DEAH-box splicing factors Prp22 and Prp16
26. PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome
27. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis
28. Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing
29. Mechanical devices of the spliceosome: Motors, clocks, springs, and things
30. Composition and functional characterization of the yeast spliceosomal penta-snRNR
31. A novel role for a U5 snRNP protein in 3′ splice site selection
32. The second catalytic step of pre-mRNA splicing
33. Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae
34. Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome
35. The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from spliceosomes and unwinds RNA duplexes
36. Functional and physical interaction between the yeast splicing factors Slu7 and Prp18