Model of the αLβ2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity

Proteins: Structure, Function and Genetics

Volumn 48, Issue 2, 2002, Pages 151-160

  Legge, Glen B ^a   Morris, Garrett M ^b   Sanner, Michel F ^b   Takada, Yoshikazu ^b   Olson, Arthur J ^b   Grynszpan, Flavio ^b  

^a University of Houston   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

L I domain; Docking; ICAM 1; Integrin, activation; Modeling

Indexed keywords

ALPHA1 BETA2 INTEGRIN I; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; UNCLASSIFIED DRUG; AMINO ACID; LIGAND; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ARTICLE; BINDING AFFINITY; CALCULATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BINDING SITES; COMPUTATIONAL BIOLOGY; INTERCELLULAR ADHESION MOLECULE-1; LIGANDS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

EID: 0036673369     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10134     Document Type: Article

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