Alzheimer's disease drug discovery targeted to the APP mRNA 5′untranslated region

Journal of Molecular Neuroscience

Volumn 19, Issue 1-2, 2002, Pages 77-82

  Rogers, J T ^a   Randall, J D ^b   Eder, P S ^c   Huang, X ^a   Bush, A I ^a   Tanzi, R E ^a   Venti, A ^a   Payton, S M ^a   Giordano, T ^c   Nagano, S ^a   Cahill, C M ^a   Moir, R ^a   Lahiri, D K ^d   Greig, N ^e   Sarang, S S ^b   Gullans, S R ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Message Pharmaceuticals Inc   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Alzheimer's disease; APP mRNA 5 untranslated region; Drug screen; FDA 2000 Drug library; RNA targeting; Translation

Indexed keywords

AMINOGLYCOSIDE; AMYLOID PRECURSOR PROTEIN; ANTIBIOTIC AGENT; CHELATING AGENT; CHOLINESTERASE INHIBITOR; DEFEROXAMINE; IRON CHELATING AGENT; LUCIFERASE; MACROLIDE; MESSENGER RNA; MUTAGENIC AGENT; NEUROLEPTIC AGENT; PHENSERINE; TOXIN;

5' UNTRANSLATED REGION; ALZHEIMER DISEASE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOD AND DRUG ADMINISTRATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; REPORTER GENE;

BACTERIA (MICROORGANISMS);

EID: 0036672706     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-002-0014-6     Document Type: Article

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