The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings

EMBO Reports

Volumn 3, Issue 8, 2002, Pages 792-797

  Yu, Xiong ^a   VanLoock, Margaret S ^a   Poplawski, Andrzej ^a   Kelman, Zvi ^a   Xiang, Tao ^a   Tye, Bik K ^a   Egelman, Edward H ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARCHAEAL PROTEIN; DNA; HELICASE; MCM PROTEIN, METHANOBACTERIUM THERMOAUTOTROPHICUM; BACTERIAL DNA; MINICHROMOSOME MAINTENANCE PROTEIN; PROTEIN SUBUNIT;

ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRON MICROSCOPY; ESCHERICHIA COLI; METABOLISM; METHANOBACTERIUM; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY; AMINO TERMINAL SEQUENCE; ARCHAEBACTERIUM; BACTERIOPHAGE T7; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA REPLICATION; EUKARYOTE; METHANOBACTERIUM THERMOAUTOTROPHICUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMINO ACID MOTIFS; ARCHAEAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA HELICASES; ESCHERICHIA COLI; METHANOBACTERIUM; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0036668640     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvf160     Document Type: Article

References (38)

1. A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast
2. A ring-opening mechanism for DNA binding in the central channel of the T7 helicase-primase protein
3. Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase
4. A 7-kDa region of the bacteriophage T7 gene 4 protein is required for primase but not for helicase activity
5. The initiation of simian virus 40 DNA replication in vitro
6. Physical and functional interaction between the MCM-like DNA helicase and the single-stranded DNA binding protein from the crenarchaeon Sulfolobus solfataricus
7. Electron microscopy of chaperonins
8. A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase
9. The simian virus 40 T antigen double hexamer assembles around the DNA at the replication origin
10. Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases
11. Further additions to MolScript version 1.4, including reading and contouring of electron-density maps
12. Structural changes in GroEL effected by binding a denatured protein substrate
13. SPIDER and WEB: Processing and visualization of images in 3D electron microscopy and related fields
14. A DNA helicase activity is associated with an MCM4,-6, and-7 protein complex
15. Global conformational transitions in Escherichia coli primary replicative helicase DnaB protein induced by ATP, ADP and single-stranded DNA binding. Multiple conformational states of the helicase hexamer
16. Improved methods for binding protein models in electron density maps and the location of errors in these models
17. The 3′-tail of a forked-duplex sterically determines whether one or two DNA strands pass through the central channel of a replication-fork helicase
18. The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum ΔH contains DNA helicase activity
19. A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication
20. Uninterrupted MCM2-7 function required for DNA replication fork progression
21. Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures
22. Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopy
23. Crystal structure of the hexameric replicative helicase RepA of plasmid RSF1010
24. Human Dmc1 protein binds DNA as an octameric ring
25. Oligomeric structure of bacteriophage T7 DNA primase/helicase proteins
26. The zinc finger domain of the archaeal minichromosome maintenance protein is required for helicase activity
27. Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity
28. Electron microscopic observation and single-stranded DNA binding activity of the Mcm4, 6, 7 complex
29. The RepA protein of plasmid RSF1010 is a replicative DNA helicase
30. The intrinsic DNA helicase activity of Methanobacterium thermoautotrophicum δ H minichromosome maintenance protein
31. Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides
32. The Escherichia coli RuvB branch migration protein forms double hexameric rings around DNA
33. MCM proteins in DNA replication
34. Insights into DNA replication from the third domain of life
35. The primase active site is on the outside of the hexameric bacteriophage T7 gene 4 helicase-primase ring
36. Structural polymorphism of the RecA protein from the thermophilic bacterium Thermus aquaticus
37. DNA is bound within the central hole to one or two of the six subunits of the T7 DNA helicase
38. Three-dimensional reconstruction of transcription termination factor ρ: Orientation of the N-terminal domain and visualization of an RNA-binding site