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Volumn 19, Issue 6 A, 1999, Pages 4831-4838

The role of oval cells and gap junctional intercellular communication in hepatocarcinogenesis

Author keywords

Gap junctions; Hepatocarcinogenesis; Intercellular communication; Oval cells

Indexed keywords

CARCINOGEN; CONNEXIN 32; CONNEXIN 43; PEPTIDE;

EID: 0033368072     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (25)

References (78)
  • 1
    • 0028352195 scopus 로고
    • The multistage nature of chemically induced hepatocarcinogenesis in the rat
    • Pilot HC and Dragan YP: The multistage nature of chemically induced hepatocarcinogenesis in the rat. Drug Metab Rev 26: 209-220, 1994.
    • (1994) Drug Metab Rev , vol.26 , pp. 209-220
    • Pilot, H.C.1    Dragan, Y.P.2
  • 2
    • 0019406463 scopus 로고
    • The sequential analysis of cancer induction with chemicals
    • Farber E: The sequential analysis of cancer induction with chemicals. Acta Pathol Jpn 31: 1-11, 1981.
    • (1981) Acta Pathol Jpn , vol.31 , pp. 1-11
    • Farber, E.1
  • 3
    • 0027892512 scopus 로고
    • Cellular origin of cancer: Dedifferentiation or stem cell maturation arrest?
    • Sell S: Cellular origin of cancer: Dedifferentiation or stem cell maturation arrest? Environ Hlth Persp 101 (suppl. 5): 15-26, 1993.
    • (1993) Environ Hlth Persp , vol.101 , Issue.SUPPL. 5 , pp. 15-26
    • Sell, S.1
  • 4
    • 0028939049 scopus 로고
    • Ductular hepatocytes
    • Sirica AE: Ductular hepatocytes. Histol Histopathol 10: 433-456, 1995.
    • (1995) Histol Histopathol , vol.10 , pp. 433-456
    • Sirica, A.E.1
  • 5
    • 0027488689 scopus 로고
    • Cell lineages in hepatic development and the identification of progenitor cells in normal and injured liver
    • Fausto N, Lemire JM and Shiojiri N: Cell lineages in hepatic development and the identification of progenitor cells in normal and injured liver. Proc Soc Exp Biol Med 204: 237-241, 1993.
    • (1993) Proc Soc Exp Biol Med , vol.204 , pp. 237-241
    • Fausto, N.1    Lemire, J.M.2    Shiojiri, N.3
  • 6
    • 0028217537 scopus 로고
    • Migration of hepatocytes along hepatic plates and stem cell-fed hepatocyte lineages
    • Grisham JW: Migration of hepatocytes along hepatic plates and stem cell-fed hepatocyte lineages. Am J Pathol 144: 849-854, 1994.
    • (1994) Am J Pathol , vol.144 , pp. 849-854
    • Grisham, J.W.1
  • 7
    • 0031898873 scopus 로고    scopus 로고
    • Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats
    • Petersen BE, Zajac VF and Michalopoulos GK: Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats. Hepatology 27: 1030-1038, 1998.
    • (1998) Hepatology , vol.27 , pp. 1030-1038
    • Petersen, B.E.1    Zajac, V.F.2    Michalopoulos, G.K.3
  • 8
    • 0031438036 scopus 로고    scopus 로고
    • Liver stem cells: When the going gets tough they get going
    • Alison MR, Golding M and Sarraf CE: Liver stem cells: when the going gets tough they get going. Int J Exp Path 78: 365-381, 1997.
    • (1997) Int J Exp Path , vol.78 , pp. 365-381
    • Alison, M.R.1    Golding, M.2    Sarraf, C.E.3
  • 10
    • 0018382741 scopus 로고
    • Junctional intercellular communication and the control of growth
    • Loewenstein WR: Junctional intercellular communication and the control of growth. Biochim Biophys Acta. 560: 1-65, 1979.
    • (1979) Biochim Biophys Acta , vol.560 , pp. 1-65
    • Loewenstein, W.R.1
  • 11
    • 0000299698 scopus 로고    scopus 로고
    • Cell-cell communication in carcinogenesis
    • Trosko JE and Ruch RJ: Cell-cell communication in carcinogenesis. Front Biosci 3: D208-D236, 1998.
    • (1998) Front Biosci , vol.3
    • Trosko, J.E.1    Ruch, R.J.2
  • 12
    • 0019815827 scopus 로고
    • Intercellular communication in normal and regenerating rat liver: A quantitative analysis
    • Meyer DJ, Yancey SB and Revel JP: Intercellular communication in normal and regenerating rat liver: a quantitative analysis. J Cell Biol 91: 505-523, 1981.
    • (1981) J Cell Biol , vol.91 , pp. 505-523
    • Meyer, D.J.1    Yancey, S.B.2    Revel, J.P.3
  • 13
    • 0027848777 scopus 로고
    • Gap functional intercellular communication and cell proliferation during rat liver carcinogenesis
    • Yamasaki H, Kjutovskikh V, Mesnil M, Columbano A, Tsuda H and Ito N: Gap functional intercellular communication and cell proliferation during rat liver carcinogenesis. Environ Health Perspect 101 (Suppl5): 191-147, 1993.
    • (1993) Environ Health Perspect , vol.101 , Issue.SUPPL. 5 , pp. 191-1147
    • Yamasaki, H.1    Kjutovskikh, V.2    Mesnil, M.3    Columbano, A.4    Tsuda, H.5    Ito, N.6
  • 14
    • 0025382389 scopus 로고
    • Role of inhibition of intercellular communication in carcinogenesis
    • Klaunig JE and Ruch RJ: Role of inhibition of intercellular communication in carcinogenesis. Lab Invest 62: 135-146, 1990.
    • (1990) Lab Invest , vol.62 , pp. 135-146
    • Klaunig, J.E.1    Ruch, R.J.2
  • 15
    • 0023621552 scopus 로고
    • Cell contact but not junctional communication (dye coupling) with biliary epithelial cells is required for hepatocytes to maintain differentiated functions
    • Mesnil M, Fraslin JM, Piccoli C, Yamasaki H, and Guguen-Guillouzo C: Cell contact but not junctional communication (dye coupling) with biliary epithelial cells is required for hepatocytes to maintain differentiated functions. Exp Cell Res 173: 524-533, 1987.
    • (1987) Exp Cell Res , vol.173 , pp. 524-533
    • Mesnil, M.1    Fraslin, J.M.2    Piccoli, C.3    Yamasaki, H.4    Guguen-Guillouzo, C.5
  • 16
    • 0030497355 scopus 로고    scopus 로고
    • Long-term maintenance of gap junctional intercellular communication and connexin32 expression by dexamethasone in rat hepatocyte-WB-F344 rat liver epithelial cell cocultures
    • Ren P and Ruch RJ: Long-term maintenance of gap junctional intercellular communication and connexin32 expression by dexamethasone in rat hepatocyte-WB-F344 rat liver epithelial cell cocultures. In Vitro Toxicol 9: 419-429, 1996.
    • (1996) In Vitro Toxicol , vol.9 , pp. 419-429
    • Ren, P.1    Ruch, R.J.2
  • 17
    • 0027196120 scopus 로고
    • Mechanisms of multistep carcinogenesis and carcinogen risk assessment
    • Barrett JC: Mechanisms of multistep carcinogenesis and carcinogen risk assessment. Environ Hlth Persp 100: 9-20, 1993.
    • (1993) Environ Hlth Persp , vol.100 , pp. 9-20
    • Barrett, J.C.1
  • 19
    • 0028559017 scopus 로고
    • Hypomethylation of DNA: An epigenetic mechanism involved in tumor promotion
    • Counts JL and Goodman JI: Hypomethylation of DNA: an epigenetic mechanism involved in tumor promotion. Mol Carcinog 11: 185-188, 1994.
    • (1994) Mol Carcinog , vol.11 , pp. 185-188
    • Counts, J.L.1    Goodman, J.I.2
  • 20
    • 0029981431 scopus 로고    scopus 로고
    • A possible role in chemical carcinogenesis for epigenetic, heritable changes in gene expression
    • MacLeod MC: A possible role in chemical carcinogenesis for epigenetic, heritable changes in gene expression. Mol Carcinog 15: 241-250, 1996.
    • (1996) Mol Carcinog , vol.15 , pp. 241-250
    • MacLeod, M.C.1
  • 21
    • 0003070587 scopus 로고
    • Epigenetic nature of neoplastic transformation
    • (Hodges G and Rowlatt M, eds). Boca raton, FL, CRC Press
    • Rubin H: Epigenetic nature of neoplastic transformation. In: Developmental Biology and Cancer (Hodges G and Rowlatt M, eds). Boca raton, FL, CRC Press, 1994, pp 61-84.
    • (1994) Developmental Biology and Cancer , pp. 61-84
    • Rubin, H.1
  • 22
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW and Vogelstein B: Lessons from hereditary colorectal cancer. Cell 87: 159-170, 1996.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 23
    • 0023911132 scopus 로고
    • Expression of the c-raf protooncogene, gamma-glutamyltranspeptidase, and gap junction protein in rat liver neoplasms
    • Beer DG, Neveu MJ, Paul DL, Rapp UR and Pilot HC: Expression of the c-raf protooncogene, gamma-glutamyltranspeptidase, and gap junction protein in rat liver neoplasms. Cancer Res 48: 1610-1617, 1988.
    • (1988) Cancer Res , vol.48 , pp. 1610-1617
    • Beer, D.G.1    Neveu, M.J.2    Paul, D.L.3    Rapp, U.R.4    Pilot, H.C.5
  • 24
    • 0031927039 scopus 로고    scopus 로고
    • Wild-type p53 expression in liver tissue and in enzyme-altered foci: An in vivo investigation on diethylnitrosamine-treated rats
    • Lennartsson P, Hogberg J and Stenius U: Wild-type p53 expression in liver tissue and in enzyme-altered foci: an in vivo investigation on diethylnitrosamine-treated rats. Carcinogenesis 19: 1231-1237, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 1231-1237
    • Lennartsson, P.1    Hogberg, J.2    Stenius, U.3
  • 25
    • 0024539690 scopus 로고
    • Phenobarbital promotion in diethylnitrosamine-initiated infant B6C3F1 mice: Influence of gender
    • Weghorst CM and Klaunig JE: Phenobarbital promotion in diethylnitrosamine-initiated infant B6C3F1 mice: influence of gender. Carcinogenesis 10: 609-612, 1989.
    • (1989) Carcinogenesis , vol.10 , pp. 609-612
    • Weghorst, C.M.1    Klaunig, J.E.2
  • 26
    • 0025032340 scopus 로고
    • DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion
    • Schulte-Hermann R, Timmermann-Trosiener I, Barthel G and Bursch W: DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion. Cancer Res 50: 5127-5135, 1990.
    • (1990) Cancer Res , vol.50 , pp. 5127-5135
    • Schulte-Hermann, R.1    Timmermann-Trosiener, I.2    Barthel, G.3    Bursch, W.4
  • 27
    • 0029891201 scopus 로고    scopus 로고
    • Karyotypic changes in a multistage model of chemical hepatocarcinogenesis in the rat
    • Sargent L, Dragan Y, Xu YH, Sattler G, Wiley J and Pilot HC: Karyotypic changes in a multistage model of chemical hepatocarcinogenesis in the rat. Cancer Res 56: 2985-2991, 1996.
    • (1996) Cancer Res , vol.56 , pp. 2985-2991
    • Sargent, L.1    Dragan, Y.2    Xu, Y.H.3    Sattler, G.4    Wiley, J.5    Pilot, H.C.6
  • 28
    • 84963089474 scopus 로고
    • The pathogenesis of tumors of the liver produced by butter yellow
    • Opie EI: The pathogenesis of tumors of the liver produced by butter yellow. J Exp Med 80: 231-246, 1944.
    • (1944) J Exp Med , vol.80 , pp. 231-246
    • Opie, E.I.1
  • 29
    • 84961012817 scopus 로고
    • Similarities in the sequences of early histological changes induced in the liver of the rat by ethionine, 2-acetylaminofluorene, and 3£-methyl-4-dimethylaminobenzene
    • Farber E: Similarities in the sequences of early histological changes induced in the liver of the rat by ethionine, 2-acetylaminofluorene, and 3£-methyl-4-dimethylaminobenzene. Cancer Res 16: 142-148, 1956.
    • (1956) Cancer Res , vol.16 , pp. 142-148
    • Farber, E.1
  • 30
    • 0019226764 scopus 로고
    • Cell types in long-lerm propagable cullures of rat liver
    • Grisham JW: Cell types in long-lerm propagable cullures of rat liver. Ann N Y Acad Sci 349: 128-137, 1980.
    • (1980) Ann N Y Acad Sci , vol.349 , pp. 128-137
    • Grisham, J.W.1
  • 31
    • 0021149409 scopus 로고
    • A diploid epithelial cell line from normal adult rat liver with phenotypic properties of "oval" cells
    • Tsao MS, Smith JD, Nelson KG and Smith JD: A diploid epithelial cell line from normal adult rat liver with phenotypic properties of "oval" cells. Exp Cell Res 154: 38-52, 1984.
    • (1984) Exp Cell Res , vol.154 , pp. 38-52
    • Tsao, M.S.1    Smith, J.D.2    Nelson, K.G.3    Smith, J.D.4
  • 32
    • 0021338957 scopus 로고
    • Isolation of oval cells by centrifugal elutriation and comparison with other cell types purified from normal and preneoplastic livers
    • Yaswen P, Hayner NT and Fausto N: Isolation of oval cells by centrifugal elutriation and comparison with other cell types purified from normal and preneoplastic livers. Cancer Res 44: 332-338, 1984.
    • (1984) Cancer Res , vol.44 , pp. 332-338
    • Yaswen, P.1    Hayner, N.T.2    Fausto, N.3
  • 33
    • 0024241798 scopus 로고
    • Neoplastic transformation and lineage switching of rat liver epithelial cells by retrovirus-associated oncogenes
    • Garfied MA, Huher BE, Nagy P, Cordingley NG and Thorgiersson SS: Neoplastic transformation and lineage switching of rat liver epithelial cells by retrovirus-associated oncogenes. Mol Carcinog 1: 189-195, 1988.
    • (1988) Mol Carcinog , vol.1 , pp. 189-195
    • Garfied, M.A.1    Huher, B.E.2    Nagy, P.3    Cordingley, N.G.4    Thorgiersson, S.S.5
  • 34
    • 0027746111 scopus 로고
    • Regulation of the differentiation of diploid and some aneuploid rat liver epithelial (stem-like) cells by the hepatic microenvironment
    • Coletnan WB, Wennenberg AE, Smith GJ and Grisham JW: Regulation of the differentiation of diploid and some aneuploid rat liver epithelial (stem-like) cells by the hepatic microenvironment. Am J Pathol 142: 1373-1382, 1993.
    • (1993) Am J Pathol , vol.142 , pp. 1373-1382
    • Coletnan, W.B.1    Wennenberg, A.E.2    Smith, G.J.3    Grisham, J.W.4
  • 35
    • 0023217079 scopus 로고
    • Hepatocarcinomas, cholangiocarcinomas, and hepatoblaslomas produced by chemically transformed cultured rat liver epithelial cells. A light- and electron-microscopic analysis
    • Tsao MS and Grisham JW: Hepatocarcinomas, cholangiocarcinomas, and hepatoblaslomas produced by chemically transformed cultured rat liver epithelial cells. A light- and electron-microscopic analysis. Am J Pathol 127: 168-181, 1987.
    • (1987) Am J Pathol , vol.127 , pp. 168-181
    • Tsao, M.S.1    Grisham, J.W.2
  • 37
    • 0027198763 scopus 로고
    • Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver parenchymal epithelial cells in vitro
    • Utesch D, Traiser M, Gath I, Dorresteijn AWC, Maier P and Oesch F: Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver parenchymal epithelial cells in vitro. Carcinogenesis 14: 457-462, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 457-462
    • Utesch, D.1    Traiser, M.2    Gath, I.3    Dorresteijn, A.W.C.4    Maier, P.5    Oesch, F.6
  • 40
    • 0025354994 scopus 로고
    • Sex differences in response to four promotion regimens in spite of common first cellular steps in the hepatocellular cancer process initiated by diethylnitrosaminc
    • Cameron RG, Blanck A and Armstrong D: Sex differences in response to four promotion regimens in spite of common first cellular steps in the hepatocellular cancer process initiated by diethylnitrosaminc. Cancer Lett 50: 109-113, 1990.
    • (1990) Cancer Lett , vol.50 , pp. 109-113
    • Cameron, R.G.1    Blanck, A.2    Armstrong, D.3
  • 41
    • 0024363412 scopus 로고
    • Different lineages of chemically induced hepatocellular carcinoma in rats defined by monoclonal antibodies
    • Dunsford HA, Karnasuta C, Hunt JM, Sell S: Different lineages of chemically induced hepatocellular carcinoma in rats defined by monoclonal antibodies. Cancer Res 49: 4894-4900, 1989.
    • (1989) Cancer Res , vol.49 , pp. 4894-4900
    • Dunsford, H.A.1    Karnasuta, C.2    Hunt, J.M.3    Sell, S.4
  • 42
    • 0028287342 scopus 로고
    • Sequential histopathological analysis of hepatocarcinogenesis in rats during promotion with orotic acid
    • Denda A, Laconi E, Rao PM, Rajalakshmi S, Sarma DS: Sequential histopathological analysis of hepatocarcinogenesis in rats during promotion with orotic acid. Cancer Lett 82: 55-64, 1994
    • (1994) Cancer Lett , vol.82 , pp. 55-64
    • Denda, A.1    Laconi, E.2    Rao, P.M.3    Rajalakshmi, S.4    Sarma, D.S.5
  • 43
    • 0028208696 scopus 로고
    • Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbitu-rates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids
    • Rice JM, Diwan BA, Hu H, Ward JM, Nims RW, and Lubet RA: Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbitu-rates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids. Carcinogenesis 15: 395-402, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 395-402
    • Rice, J.M.1    Diwan, B.A.2    Hu, H.3    Ward, J.M.4    Nims, R.W.5    Lubet, R.A.6
  • 44
    • 0021849770 scopus 로고
    • The modulation of growth of normal rat liver epithelial cells in calcium-poor medium by epidermal growth factor, phenobarbital, phorbol ester, and retinoic acid
    • Tsao MS, Smith JD and Grisham JW: The modulation of growth of normal rat liver epithelial cells in calcium-poor medium by epidermal growth factor, phenobarbital, phorbol ester, and retinoic acid. In Vitro Cell Dev Biol 21: 249-253, 1985.
    • (1985) In Vitro Cell Dev Biol , vol.21 , pp. 249-253
    • Tsao, M.S.1    Smith, J.D.2    Grisham, J.W.3
  • 45
    • 0017732554 scopus 로고
    • Effects of varying the onset and duration of exposure to phenobarbital on its enhancement of 2-acetylaminofluorenc-induced hepatic tumorigenesis
    • Peraino C, Fry RJ and Staffeldt E: Effects of varying the onset and duration of exposure to phenobarbital on its enhancement of 2-acetylaminofluorenc-induced hepatic tumorigenesis. Cancer Res 37: 3623-3627, 1977.
    • (1977) Cancer Res , vol.37 , pp. 3623-3627
    • Peraino, C.1    Fry, R.J.2    Staffeldt, E.3
  • 46
    • 0024787405 scopus 로고
    • Sequence and tissue distribution of a second protein of hepatic gap junctions. Cx26, as deduced from its cDNA
    • Zhang JT and Nicholson BJ: Sequence and tissue distribution of a second protein of hepatic gap junctions. Cx26, as deduced from its cDNA. J Cell Biol 109: 3391-3401, 1989.
    • (1989) J Cell Biol , vol.109 , pp. 3391-3401
    • Zhang, J.T.1    Nicholson, B.J.2
  • 47
    • 0028177936 scopus 로고
    • Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver
    • Neveu M, Hully J, Babcock K, Hertzberg E, Nicholson B, Paul D and Pilot H: Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver. J Cell Sci 707: 83-95, 1994.
    • (1994) J Cell Sci , vol.707 , pp. 83-95
    • Neveu, M.1    Hully, J.2    Babcock, K.3    Hertzberg, E.4    Nicholson, B.5    Paul, D.6    Pilot, H.7
  • 48
    • 0026320779 scopus 로고
    • Characterization of and interactions between ductule cells and hepatocytes in early stages of rat hepatocarcinogenesis studies by ethionine
    • Novikoff PM, Ikeda T, Hixson DC and Yam A: Characterization of and interactions between ductule cells and hepatocytes in early stages of rat hepatocarcinogenesis studies by ethionine. Am J Pathol 139: 1352-1368, 1991.
    • (1991) Am J Pathol , vol.139 , pp. 1352-1368
    • Novikoff, P.M.1    Ikeda, T.2    Hixson, D.C.3    Yam, A.4
  • 49
    • 0029739466 scopus 로고    scopus 로고
    • Localization and function of the connexin 43 gap-junction protein in normal and various oncogene-expressing rat liver epithelial cells
    • de Feijter AW, Matesic DF, Ruch RJ, Guan X, Chang CC and Trosko JE: Localization and function of the connexin 43 gap-junction protein in normal and various oncogene-expressing rat liver epithelial cells. Mol Carcinog 16: 2113-212, 1996.
    • (1996) Mol Carcinog , vol.16 , pp. 2113-2212
    • De Feijter, A.W.1    Matesic, D.F.2    Ruch, R.J.3    Guan, X.4    Chang, C.C.5    Trosko, J.E.6
  • 50
    • 0027979778 scopus 로고
    • Establishment and characterization of differentiated, nontransformed hepatocytc cell lines derived from mice transgenic for transforming growth factor alpha
    • Wu JC, Merlino G and Fausto N: Establishment and characterization of differentiated, nontransformed hepatocytc cell lines derived from mice transgenic for transforming growth factor alpha. Proc Nail Acad Sci USA 91: 674-678, 1994.
    • (1994) Proc Nail Acad Sci USA , vol.91 , pp. 674-678
    • Wu, J.C.1    Merlino, G.2    Fausto, N.3
  • 51
    • 0028290566 scopus 로고
    • Modulation of connexins during differentiation of oval cells into hepatocytes
    • Zhang M and Thorgeirsson SS: Modulation of connexins during differentiation of oval cells into hepatocytes. Exp Cell Res 213: 37-42, 1994.
    • (1994) Exp Cell Res , vol.213 , pp. 37-42
    • Zhang, M.1    Thorgeirsson, S.S.2
  • 53
    • 0031582224 scopus 로고    scopus 로고
    • How the neighborhood coherence principle (NCP) can give rise to tissue homeostasis: A cellular automaton approach
    • Phipps M, Darozewski J and Phipps J: How the neighborhood coherence principle (NCP) can give rise to tissue homeostasis: a cellular automaton approach. J Theor Biol 185: 475-487, 1997.
    • (1997) J Theor Biol , vol.185 , pp. 475-487
    • Phipps, M.1    Darozewski, J.2    Phipps, J.3
  • 55
    • 0030928698 scopus 로고    scopus 로고
    • Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype
    • Martyn KD, Kurata WE, Warn-Cramer BJ, Burt JM, TenBroek E and Lau AF: Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype. Cell Growth Differ 8: 1015-1027, 1997.
    • (1997) Cell Growth Differ , vol.8 , pp. 1015-1027
    • Martyn, K.D.1    Kurata, W.E.2    Warn-Cramer, B.J.3    Burt, J.M.4    TenBroek, E.5    Lau, A.F.6
  • 57
    • 0031240077 scopus 로고    scopus 로고
    • High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32
    • Temme A, Buchmann A, Gabriel HD, Nelles E, Schwarz M and Willecke K: High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32. Curr Biol 7: 713-716, 1997.
    • (1997) Curr Biol , vol.7 , pp. 713-716
    • Temme, A.1    Buchmann, A.2    Gabriel, H.D.3    Nelles, E.4    Schwarz, M.5    Willecke, K.6
  • 58
    • 0025784401 scopus 로고
    • Sequential changes of gap-junctional intercellular communications during multistage rat liver carcinogenesis: Direct measurement of communication in vivo
    • Krutovskikh VA, Oyamada M and Yamasaki H: Sequential changes of gap-junctional intercellular communications during multistage rat liver carcinogenesis: direct measurement of communication in vivo. Carcinogenesis 12: 1701-1706, 1991.
    • (1991) Carcinogenesis , vol.12 , pp. 1701-1706
    • Krutovskikh, V.A.1    Oyamada, M.2    Yamasaki, H.3
  • 59
    • 0027093421 scopus 로고
    • Differential changes in expression of gap junction proteins connexin 26 and 32 during hepatocarcinogenesis in rats
    • Sakamoto H, Oyamada M, Enomoto K and Mori M: Differential changes in expression of gap junction proteins connexin 26 and 32 during hepatocarcinogenesis in rats. Jpn J Cancer Res 83: 1210-1215, 1992.
    • (1992) Jpn J Cancer Res , vol.83 , pp. 1210-1215
    • Sakamoto, H.1    Oyamada, M.2    Enomoto, K.3    Mori, M.4
  • 60
    • 0030451490 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of the gap junctional protein connexin 32 and proliferating cell nuclear antigen in glutathione S-transterase placental form-negative lesions of rat liver induced by diethylnitrosamine and clofibrate
    • Ito S, Tateno C, Tuda M and Yoshitake A: Immunohistochemical demonstration of the gap junctional protein connexin 32 and proliferating cell nuclear antigen in glutathione S-transterase placental form-negative lesions of rat liver induced by diethylnitrosamine and clofibrate. Toxicol Pathol 24: 690-695, 1996.
    • (1996) Toxicol Pathol , vol.24 , pp. 690-695
    • Ito, S.1    Tateno, C.2    Tuda, M.3    Yoshitake, A.4
  • 62
    • 0028084968 scopus 로고
    • Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumors associated with aberrant protein localization but not gene mutation of connexin 32
    • Krutovskikh V, Mazzoleni G, Mironov N, Omori Y, Aguelon AM, Mesnil M, Berger F, Partensky C and Yamasaki H: Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumors associated with aberrant protein localization but not gene mutation of connexin 32. Int J Cancer 56: 87-94, 1994.
    • (1994) Int J Cancer , vol.56 , pp. 87-94
    • Krutovskikh, V.1    Mazzoleni, G.2    Mironov, N.3    Omori, Y.4    Aguelon, A.M.5    Mesnil, M.6    Berger, F.7    Partensky, C.8    Yamasaki, H.9
  • 64
    • 0031042893 scopus 로고    scopus 로고
    • Connexin 37 mutations in rat hepatic angiosarcomas induced by vinyl chloride
    • Saito T, Barbin A, Omori Y and Yamasaki H: Connexin 37 mutations in rat hepatic angiosarcomas induced by vinyl chloride. Cancer Res 57: 375-377, 1997.
    • (1997) Cancer Res , vol.57 , pp. 375-377
    • Saito, T.1    Barbin, A.2    Omori, Y.3    Yamasaki, H.4
  • 66
    • 0018149578 scopus 로고
    • Phenotypic diversity in experimental hepatomas: The concept of partially blocked ontogeny
    • Potter VP: Phenotypic diversity in experimental hepatomas: The concept of partially blocked ontogeny. Br J Cancer 38: 1-23, 1978.
    • (1978) Br J Cancer , vol.38 , pp. 1-23
    • Potter, V.P.1
  • 67
    • 0021331065 scopus 로고
    • Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylamino-fluorene, phenobarbital and 4,4'-diaminodiphenylmethane: A sequential histological and histochemical analysis
    • Ito N, Moore MA and Bannasch P: Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylamino-fluorene, phenobarbital and 4,4'-diaminodiphenylmethane: a sequential histological and histochemical analysis. Carcinogenesis 5: 335-342, 1984.
    • (1984) Carcinogenesis , vol.5 , pp. 335-342
    • Ito, N.1    Moore, M.A.2    Bannasch, P.3
  • 68
    • 0028077587 scopus 로고
    • Dissimilar frequency of hepatoblastomas and hepatic cystadenomas and adenocarcinomas arising in hepatocellular neoplasms of D2B6F1 mice initiated with N-nitrosodiethylamine and subsequently given Aroclor-1254, dichlorodiphenyltrichloroethane, or phenobarbital
    • Diwan BA, Ward JM, Kurata Y and Rice JM. Dissimilar frequency of hepatoblastomas and hepatic cystadenomas and adenocarcinomas arising in hepatocellular neoplasms of D2B6F1 mice initiated with N-nitrosodiethylamine and subsequently given Aroclor-1254, dichlorodiphenyltrichloroethane, or phenobarbital. Toxicol Pathol 22: 430-439, 1994.
    • (1994) Toxicol Pathol , vol.22 , pp. 430-439
    • Diwan, B.A.1    Ward, J.M.2    Kurata, Y.3    Rice, J.M.4
  • 69
    • 0031819436 scopus 로고    scopus 로고
    • Inhibition of gap junctional intercellular communication by tumor promoters in connexin43 and connexin32-expressing liver cells: Cell specificity and role of protein kinase C
    • Ren P, Mehta PP and Ruch RJ: Inhibition of gap junctional intercellular communication by tumor promoters in connexin43 and connexin32-expressing liver cells: cell specificity and role of protein kinase C. Carcinogenesis 19: 169-175, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 169-175
    • Ren, P.1    Mehta, P.P.2    Ruch, R.J.3
  • 70
    • 0023134831 scopus 로고
    • Inhibition of intercellular communication between mouse hepatocytes by tumor promoters
    • Ruch RJ, Klaunig JE and Pereira MA: Inhibition of intercellular communication between mouse hepatocytes by tumor promoters. Toxicol Appl Pharmacol 87: 111-120, 1987.
    • (1987) Toxicol Appl Pharmacol , vol.87 , pp. 111-120
    • Ruch, R.J.1    Klaunig, J.E.2    Pereira, M.A.3
  • 71
    • 0031894791 scopus 로고    scopus 로고
    • Inhibition of cell-cell communication by methylsulfonyl metabolites of polychlorinated biphenyl congeners in rat liver epithelial IAR 20 cells
    • Kato Y, Kenne K, Haraguchi K, Masuda Y, Kimura R and Warngard L: Inhibition of cell-cell communication by methylsulfonyl metabolites of polychlorinated biphenyl congeners in rat liver epithelial IAR 20 cells. Arch Toxicol 72: 178-182, 1998.
    • (1998) Arch Toxicol , vol.72 , pp. 178-182
    • Kato, Y.1    Kenne, K.2    Haraguchi, K.3    Masuda, Y.4    Kimura, R.5    Warngard, L.6
  • 73
    • 0023125562 scopus 로고
    • Cyclic adenosine monophosphate stimulates biosynthesis and phosphorylation of the 26 kDa gap junction protein in cultured mouse hepatocytes
    • Traub O, Look J, Paul D and Willecke K: Cyclic adenosine monophosphate stimulates biosynthesis and phosphorylation of the 26 kDa gap junction protein in cultured mouse hepatocytes. Eur J Cell Biol 43: 48-54, 1987.
    • (1987) Eur J Cell Biol , vol.43 , pp. 48-54
    • Traub, O.1    Look, J.2    Paul, D.3    Willecke, K.4
  • 74
    • 0030817125 scopus 로고    scopus 로고
    • Different changes in expression and function of connexin 26 and connexin 32 during DNA synthesis and redifferentiation in primary rat hepatocytes using a DMSO culture system
    • Kojima T, Yamamoto M, Mochizuki C, Mitaka T, Sawada N and Mochizuki Y: Different changes in expression and function of connexin 26 and connexin 32 during DNA synthesis and redifferentiation in primary rat hepatocytes using a DMSO culture system. Hepatology 26: 585-597, 1997.
    • (1997) Hepatology , vol.26 , pp. 585-597
    • Kojima, T.1    Yamamoto, M.2    Mochizuki, C.3    Mitaka, T.4    Sawada, N.5    Mochizuki, Y.6
  • 75
    • 0027256095 scopus 로고
    • An improved long-term culture of rat hepatocytes to detect liver tumour-promoting agents: Results with phenobarbital
    • Mesnil M, Piccoli C and Yamasaki H: An improved long-term culture of rat hepatocytes to detect liver tumour-promoting agents: results with phenobarbital. Eur J Pharmacol 248: 59-66, 1993.
    • (1993) Eur J Pharmacol , vol.248 , pp. 59-66
    • Mesnil, M.1    Piccoli, C.2    Yamasaki, H.3
  • 78
    • 0028047589 scopus 로고
    • The connexin43 gene is responsive to oestrogen
    • Yu W, Dahl G and Werner R: The connexin43 gene is responsive to oestrogen. Proc R Soc Lond B Biol Sci 255: 125-132, 1994.
    • (1994) Proc R Soc Lond B Biol Sci , vol.255 , pp. 125-132
    • Yu, W.1    Dahl, G.2    Werner, R.3


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