Promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin and 17β-estradiol in male Sprague-Dawley rats

Toxicological Sciences

Volumn 68, Issue 2, 2002, Pages 295-303

  Wyde, Michael E ^a,b   Cambre, Theresa ^a   Lebetkin, Mark ^a   Eldridge, Sandra R ^c   Walker, Nigel J ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c CHARLES RIVER LABORATORIES   (United States)

Author keywords

Carcinogenesis; Dioxin; Estrogen; Oxidative damage; Promotion cell proliferation

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CORN OIL; DIETHYLNITROSAMINE; DNA; ESTRADIOL; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; CARCINOGEN; CYTOCHROME P450 1A1; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; FEMALE; HORMONAL REGULATION; LIVER CARCINOGENESIS; MALE; NONHUMAN; PLACENTA; PRECANCER; RAT; SEX DIFFERENCE; TUMOR PROMOTION; ANIMAL; BIOSYNTHESIS; CARCINOGEN TESTING; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMAL; CARCINOGENICITY TESTS; CARCINOGENS; CELL DIVISION; CYTOCHROME P-450 CYP1A1; DIETHYLNITROSAMINE; DRUG ANTAGONISM; ESTRADIOL; GAMMA-GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; LIVER NEOPLASMS, EXPERIMENTAL; MALE; PRECANCEROUS CONDITIONS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN; ANIMALS;

ANIMALIA; ZEA MAYS;

EID: 0036667352     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/68.2.295     Document Type: Article

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