Quantitative analysis of dose- and time-dependent promotion of four phenotypes of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats

Toxicological Sciences

Volumn 51, Issue 2, 1999, Pages 211-223

  Teeguarden, Justin G ^a,b   Dragan, Yvonne P ^a   Singh, Jodi ^a   Vaughan, Jennifer ^a   Xu, Y H ^a   Goldsworthy, Thomas ^c   Pitot, Henry C ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c INTEGRATED LABORATORY SYSTEMS   (United States)

Author keywords

glutamyl transpeptidase (GGT); 2,3,7,8 tetrachlorodibenzo p dioxin (TCDD); Altered hepatic foci; Canalicular adenosine triphosphatase (ATPase); Carcinogens; Cell proliferation; Dose response; Glucose 6 phosphatase (G6P); Glutathione s transferase (GSTP); Liver; Non genotoxic; Promotion; Sprague Dawley rats

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ADENOSINE TRIPHOSPHATASE; DIETHYLNITROSAMINE; GLUCOSE 6 PHOSPHATASE; GLUTATHIONE TRANSFERASE; TUMOR PROMOTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; LIVER CARCINOGENESIS; LIVER CELL; LIVER WEIGHT; NONHUMAN; PARTIAL HEPATECTOMY; PHENOTYPE; RAT;

ALKYLATING AGENTS; ANIMALS; CARCINOGENS; DIETHYLNITROSAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTATHIONE TRANSFERASE; LIVER; LIVER NEOPLASMS; ORGAN SIZE; PHENOTYPE; PRECANCEROUS CONDITIONS; RATS; RATS, SPRAGUE-DAWLEY; TERATOGENS; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

ANIMALIA;

EID: 0032722545     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/51.2.211     Document Type: Article

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