메뉴 건너뛰기




Volumn 8, Issue 3, 2002, Pages 284-286

The IARC evaluation of Di(2-ethylhexyl)phthalate (DEHP): A flawed decision based on an untested hypothesis

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A OXIDASE; CARCINOGEN; CIPROFLOXACIN; CLOFIBRATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; RETINOID X RECEPTOR;

EID: 0036656862     PISSN: 10773525     EISSN: None     Source Type: Journal    
DOI: 10.1179/oeh.2002.8.3.284     Document Type: Note
Times cited : (11)

References (24)
  • 1
    • 0035325333 scopus 로고    scopus 로고
    • Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)-phthalate (DEHP)?
    • Melnick RL. Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)? Environ Health Perspect. 2001;109:437-42.
    • (2001) Environ Health Perspect , vol.109 , pp. 437-442
    • Melnick, R.L.1
  • 3
    • 0036238250 scopus 로고    scopus 로고
    • The IARC monographs program: Changing attitudes towards public health
    • Tomatis L. The IARC monographs program: changing attitudes towards public health. Int J Occup Environ Health. 2002;8:144-52.
    • (2002) Int J Occup Environ Health , vol.8 , pp. 144-152
    • Tomatis, L.1
  • 4
    • 0032102436 scopus 로고    scopus 로고
    • Effect of rodent hepatocarcinogenic peroxisome proliferators on fatty acyl-CoA oxidase, DNA synthesis, and apoptosis in cultured human and rat hepatocytes
    • Perrone CE, Shao L, Williams GM. Effect of rodent hepatocarcinogenic peroxisome proliferators on fatty acyl-CoA oxidase, DNA synthesis, and apoptosis in cultured human and rat hepatocytes. Toxicol Appl Pharmacol. 1998;150:277-86.
    • (1998) Toxicol Appl Pharmacol , vol.150 , pp. 277-286
    • Perrone, C.E.1    Shao, L.2    Williams, G.M.3
  • 5
    • 0033001883 scopus 로고    scopus 로고
    • A cancer risk assessment of di(2-ethyl-hexyl)phthalate: Application of the new U.S. EPA risk assessment guidelines
    • Doull J, Cattley R, Elcombe C, et al. A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA risk assessment guidelines. Regul Toxicol Pharmacol. 1999;29:327-57.
    • (1999) Regul Toxicol Pharmacol , vol.29 , pp. 327-357
    • Doull, J.1    Cattley, R.2    Elcombe, C.3
  • 8
    • 0032995560 scopus 로고    scopus 로고
    • The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: Significance for species differences in response to PPs
    • Woodyatt NJ, Lambe KG, Myers KA, Tugwood JD, Roberts RA. The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs. Carcinogenesis. 1999;20:369-72.
    • (1999) Carcinogenesis , vol.20 , pp. 369-372
    • Woodyatt, N.J.1    Lambe, K.G.2    Myers, K.A.3    Tugwood, J.D.4    Roberts, R.A.5
  • 9
    • 0035197591 scopus 로고    scopus 로고
    • Peroxisome proliferators: Response
    • Melnick RL. Peroxisome proliferators: response. Environ Health Perspect. 2001;109:A463-64.
    • (2001) Environ Health Perspect , vol.109
    • Melnick, R.L.1
  • 10
    • 0035093629 scopus 로고    scopus 로고
    • Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats
    • Biegel LB, Hurtt ME, Frame SR, O'Connor JC, Cook JC. Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats. Toxicol Sci. 2001;60:44-55.
    • (2001) Toxicol Sci , vol.60 , pp. 44-55
    • Biegel, L.B.1    Hurtt, M.E.2    Frame, S.R.3    O'Connor, J.C.4    Cook, J.C.5
  • 11
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
    • Peters JM, Cattley RC, Gonzalez FJ. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis. 1997;18:2029-33.
    • (1997) Carcinogenesis , vol.18 , pp. 2029-2033
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 13
    • 0027299459 scopus 로고
    • Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation
    • Melnick RL, Huff J. Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation. Toxicol Ind Health. 1993;9:415-38.
    • (1993) Toxicol Ind Health , vol.9 , pp. 415-438
    • Melnick, R.L.1    Huff, J.2
  • 14
    • 0029119082 scopus 로고
    • Fibrates increase human apolipo-protein A-II expression through activation of the peroxisome proliferator-activated receptor
    • Vu-Dac N, Schoonjans K, Kosykh V, et al. Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J Clin Invest. 1995;96:741-50.
    • (1995) J Clin Invest , vol.96 , pp. 741-750
    • Vu-Dac, N.1    Schoonjans, K.2    Kosykh, V.3
  • 15
    • 0035943681 scopus 로고    scopus 로고
    • Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR)α
    • Lawrence JW, Li Y, Chen S, et al. Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR)α. J Biol Chem. 2001;276:31521-7.
    • (2001) J Biol Chem , vol.276 , pp. 31521-31527
    • Lawrence, J.W.1    Li, Y.2    Chen, S.3
  • 16
    • 0035958960 scopus 로고    scopus 로고
    • Identification of peroxisome proliferator-responsive human genes by elevated expression of peroxisome proliferator-activated receptor) α in HepG2 cells
    • Hsu MH, Savas U, Griffin KJ, Johnson EF. Identification of peroxisome proliferator-responsive human genes by elevated expression of peroxisome proliferator-activated receptor) α in HepG2 cells. J Biol Chem. 2001;276:27950-8.
    • (2001) J Biol Chem , vol.276 , pp. 27950-27958
    • Hsu, M.H.1    Savas, U.2    Griffin, K.J.3    Johnson, E.F.4
  • 18
    • 0034886485 scopus 로고    scopus 로고
    • Mouse hepatocyte response to peroxisome proliferators: Dependency on hepatic nonparenchymal cells and peroxisome proliferator activated receptor α (PPARα)
    • Hasmall S, James N, Hedley K, Olsen K, Roberts R. Mouse hepatocyte response to peroxisome proliferators: dependency on hepatic nonparenchymal cells and peroxisome proliferator activated receptor α (PPARα). Arch Toxicol. 2001;75:357-61.
    • (2001) Arch Toxicol , vol.75 , pp. 357-361
    • Hasmall, S.1    James, N.2    Hedley, K.3    Olsen, K.4    Roberts, R.5
  • 19
    • 0034052579 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (is restricted to hepatic parenchymal cells, not Kupffer cells: Implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis
    • Peters JM, Rusyn I, Rose ML, Gonzalez FJ, Thurman RG. Peroxisome proliferator-activated receptor (is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis. Carcinogenesis. 2000;21:823-6.
    • (2000) Carcinogenesis , vol.21 , pp. 823-826
    • Peters, J.M.1    Rusyn, I.2    Rose, M.L.3    Gonzalez, F.J.4    Thurman, R.G.5
  • 20
    • 0034282768 scopus 로고    scopus 로고
    • Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators
    • Rusyn I, Yamashina S, Segal BH, et al. Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators. Cancer Res. 2000;60:4798-803.
    • (2000) Cancer Res , vol.60 , pp. 4798-4803
    • Rusyn, I.1    Yamashina, S.2    Segal, B.H.3
  • 21
    • 0035061472 scopus 로고    scopus 로고
    • Phthalates rapidly increase production of reactive oxygen species in vivo: Role of Kupffer cells
    • Rusyn I, Kadiiska MB, Dikalova A, et al. Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells. Mol Pharmacol. 2001;59:744-50.
    • (2001) Mol Pharmacol , vol.59 , pp. 744-750
    • Rusyn, I.1    Kadiiska, M.B.2    Dikalova, A.3
  • 22
    • 0030841938 scopus 로고    scopus 로고
    • Recent update on the PPAR alpha-null mouse
    • Gonzalez FJ. Recent update on the PPAR alpha-null mouse. Biochimie. 1997;79:139-44.
    • (1997) Biochimie , vol.79 , pp. 139-144
    • Gonzalez, F.J.1
  • 23
    • 0030766476 scopus 로고    scopus 로고
    • Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice
    • Peters JM, Hennuyer N, Staels B, et al. Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice. J Biol Chem. 1997;272:27307-12.
    • (1997) J Biol Chem , vol.272 , pp. 27307-27312
    • Peters, J.M.1    Hennuyer, N.2    Staels, B.3
  • 24
    • 0029084409 scopus 로고
    • Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor. Possible role of a leucine zipper-like heptad repeat
    • Juge-Aubry CE, Gorla-Bajszczak A, Pernin A, et al. Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for retinoid X receptor. Possible role of a leucine zipper-like heptad repeat. J Biol Chem. 1995;270:18117-22.
    • (1995) J Biol Chem , vol.270 , pp. 18117-18122
    • Juge-Aubry, C.E.1    Gorla-Bajszczak, A.2    Pernin, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.