Reduction of rat brain levels of the endogenous dopaminergic proneurotoxins 1,2,3,4-tetrahydroisoquinoline and 1,2,3,4-tetrahydro-β-carboline by cigarette smoke

Neuroscience Letters

Volumn 298, Issue 3, 2001, Pages 187-190

  Soto Otero, Ramón ^a   Méndez Álvarez, Estefanía ^a   Sánchez Sellero, Inés ^a   Cruz Landeira, Angelines ^a   Lamas, Manuel López Rivadulla ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

1,2,3,4 Tetrahydro carbolin e; 1,2,3,4 Tetrahydroisoquinoline; Bright tobacco; Burley tobacco; Cigarette smoke; Dopaminergic neurotoxins; Parkinson's disease; Rat brain

Indexed keywords

ACID ANHYDRIDE; CIGARETTE SMOKE; NEUROTOXIN; PROPIONIC ACID; TETRAHYDROISOQUINOLINE; TRYPTOLINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN LEVEL; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; GAS CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

ANIMALS; BRAIN; CARBOLINES; DOPAMINE; ISOQUINOLINES; MALE; NEUROTOXINS; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; SMOKING; TETRAHYDROISOQUINOLINES;

EID: 0035830774     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01746-8     Document Type: Article

References (20)

1. Identification and quantification of 1,2,3,4-tetrahydro-beta-carboline, 2-methyl-1,2,3,4-tetrahydro-beta-carboline, and 6-methoxy-1,2,3,4-tetrahydro-beta-carboline as in vivo constituents of rat brain and adrenal gland
2. Cigarette smoking and Parkinson's disease
3. Endogenous toxins as potential etiological agents in Parkinson's disease
4. Quantitative gas chromatographic mass spectrometric determination of 1,2,3,4-tetrahydro-β-carboline in human plasma and platelets
5. Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain
6. Occurrence of neurotoxic β-carbolinium cations in mammalian central nervous system
7. The routes and significance of endogenous synthesis of alkaloids in animal
8. Inhibition of brain monoamino oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke
9. Isoquinoline neurotoxins in the brain and Parkinson's disease
10. A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroiso-quinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopamnergic neurotoxin, N-methylisoquinolinium ion
11. +)
12. A retrospective study of smoking in Parkinson's disease
13. Smoking and Parkinson's disease: A case-control study in Germany
14. Presence of tetrahydroisoquinoline and 2-methyl-tetrahydroisoquinoline in parkinsonian and normal human brains
15. The distribution of cigarette smoke components between mainstream and sidestream smoke: I. Acidic components
16. The distribution of cigarette smoke components between mainstream and sidestream smoke: II. Bases
17. The distribution of cigarette smoke components between mainstream and sidestream smoke: III. Middle and higher boiling components
18. Studies on the interaction between 1,2,3,4-tetrahydro-β-carboline and cigarette smoke: A potential mechanism of neuroprotection for Parkinson's disease
19. Interaction of 1,2,3,4-tetrahydroisoquinoline with some components of cigarette smoke: Potential implications for Parkinson's disease
20. Inhibition of mitochondrial NADH-ubiquinone oxidoreductase and ATP synthesis by tetrahydroisoquinoline