Nucleocytoplasmic transport of nuclear factor κB and its regulatory mechanisms

Progress in Biochemistry and Biophysics

Volumn 29, Issue 3, 2002, Pages 368-372

  Shen, Li Qun ^a   Xu, Xiang ^a   Lü, Feng Lin ^a   Liang, Hua Ping ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Inhibitory protein B (I B); Nuclear export signal (NES); Nuclear factor B (NF B); Nuclear localization signal (NLS); Nucleocytoplasmic transport

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RAN PROTEIN;

CELL NUCLEUS; CYTOPLASM; ENERGY; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR PORE COMPLEX; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; REVIEW;

EID: 0036591330     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (20)

1. Nuclear pores and nuclear assembly
2. Transport between the cell nucleus and the cytoplasm
3. Transport of proteins and RNAs in and out of the nucleus
4. Importins and exportins: How to get in and out of the nucleus
5. Nuclear import of IκBα is accomplished by a ran-independent transport pathway
6. A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes
7. IκBα and IκBα/NF-κB complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2
8. Nucleocytoplasmic transport enters the atomic age
9. NF-κB to the rescue: RELs, apoptosis and cellular transformation
10. NF-κB: Ten years after
11. Serine 32 and serine 36 of IkappaBalpha are directly phosphorylated by protein kinase CK II in vitro
12. Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription
13. Activation of phosphatidylinositol 3 kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit
14. Characterization of IkappaBalpha nuclear import pathway
15. Identification of the nuclear localization signal of mouse DNA primase: Nuclear transport of p46 subunit is facilitated by interaction with p54 subunit
16. Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB
17. BCL3 encodes a nuclear protein which can alter the subcellular location of NF-κB proteins
18. Nucleocytoplasmic shutting of transcription factors
19. The crystal structure of the IκBα/NF-κB complex reveals mechanisms of NF-κB inactivation
20. IκB family members function by different mechanisms