Bifonazole, but not the structurally-related clotrimazole, induces both peroxisome proliferation and members of the cytochrome P4504A sub-family in rat liver

Toxicology

Volumn 106, Issue 1-3, 1996, Pages 19-26

  Sabzevari, Omid ^a   Hatcher, Malcolm ^b   Kentish, Peter ^a   O'Sullivan, Mike ^b   Gibson, G Gordon ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b GENERAL ELECTRIC COMPANY   (United States)

Author keywords

Bifonazole; Clotrimazole; Cytochrome P4504A; Enzyme induction; Peroxisome proliferators

Indexed keywords

BIFONAZOLE; CLOFIBRATE; CLOTRIMAZOLE; CYTOCHROME P450 ISOENZYME; OXYGENASE; PEROXISOME PROLIFERATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; HEPATOMEGALY; LIVER; LIVER MICROSOME; LIVER TOXICITY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0030071101     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0300-483X(95)03150-E     Document Type: Article

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