-
1
-
-
0026335130
-
-
B. A. Barres, J. Neurosci. 11, 3685 (1991); F. W. Pfrieger and B. A. Barres, Science 277, 1684 (1997).
-
(1991)
J. Neurosci.
, vol.11
, pp. 3685
-
-
Barres, B.A.1
-
2
-
-
0030773837
-
-
B. A. Barres, J. Neurosci. 11, 3685 (1991); F. W. Pfrieger and B. A. Barres, Science 277, 1684 (1997).
-
(1997)
Science
, vol.277
, pp. 1684
-
-
Pfrieger, F.W.1
Barres, B.A.2
-
3
-
-
0344316022
-
-
J. T. Littleton, M. A. Bhat, H. J. Bellen, J. Cell Biol. 137, (1997); M. Missler and T. C. Sudhof, Trends Genet. 14, 20 (1998); H. J. Bellen, Y. Lu, R. Beckstead, M. A. Bhat, Trends Neurosci. 21, 444 (1998).
-
(1997)
J. Cell Biol.
, vol.137
-
-
Littleton, J.T.1
Bhat, M.A.2
Bellen, H.J.3
-
4
-
-
0031983653
-
-
J. T. Littleton, M. A. Bhat, H. J. Bellen, J. Cell Biol. 137, (1997); M. Missler and T. C. Sudhof, Trends Genet. 14, 20 (1998); H. J. Bellen, Y. Lu, R. Beckstead, M. A. Bhat, Trends Neurosci. 21, 444 (1998).
-
(1998)
Trends Genet.
, vol.14
, pp. 20
-
-
Missler, M.1
Sudhof, T.C.2
-
5
-
-
0031720684
-
-
J. T. Littleton, M. A. Bhat, H. J. Bellen, J. Cell Biol. 137, (1997); M. Missler and T. C. Sudhof, Trends Genet. 14, 20 (1998); H. J. Bellen, Y. Lu, R. Beckstead, M. A. Bhat, Trends Neurosci. 21, 444 (1998).
-
(1998)
Trends Neurosci.
, vol.21
, pp. 444
-
-
Bellen, H.J.1
Lu, Y.2
Beckstead, R.3
Bhat, M.A.4
-
6
-
-
0030582713
-
-
S. Baumgartner et al., Cell 87, 1059 (1996).
-
(1996)
Cell
, vol.87
, pp. 1059
-
-
Baumgartner, S.1
-
7
-
-
0031041601
-
-
E. Peles et al., EMBO J. 16, 978 (1997); S. Einheber et al., J. Cell Biol. 139, 1495 (1997); M. Menegoz et al., Neuron 19, 319 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 978
-
-
Peles, E.1
-
8
-
-
0031453392
-
-
E. Peles et al., EMBO J. 16, 978 (1997); S. Einheber et al., J. Cell Biol. 139, 1495 (1997); M. Menegoz et al., Neuron 19, 319 (1997).
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1495
-
-
Einheber, S.1
-
9
-
-
0030772073
-
-
E. Peles et al., EMBO J. 16, 978 (1997); S. Einheber et al., J. Cell Biol. 139, 1495 (1997); M. Menegoz et al., Neuron 19, 319 (1997).
-
(1997)
Neuron
, vol.19
, pp. 319
-
-
Menegoz, M.1
-
10
-
-
0344748283
-
-
note
-
P12 homozygotes appeared normal at 20° to 22 °C but became paralyzed within 3 min at 37° to 38 °C. Full recovery occurred at 20° to 22 °C within 7 to 8 min.
-
-
-
-
12
-
-
0028233978
-
-
Five to 10 mg of polyadenylated RNA were loaded in each lane
-
Northern blot analysis was performed as described [R. W. Ordway, L. Pallanck, B. Ganetzky, Proc. Natl. Acad. Sci. U.S.A. 91, 5715 (1994)]. Five to 10 mg of polyadenylated RNA were loaded in each lane.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 5715
-
-
Ordway, R.W.1
Pallanck, L.2
Ganetzky, B.3
-
13
-
-
0024976602
-
-
K. Loughney, R. Kreber, B. Ganetzky, Cell 58, 1143 (1989); M. J. Kernan, M. I. Kuroda, R. Kreber, B. S. Baker, B. Ganetzky, ibid. 66, 949 (1991).
-
(1989)
Cell
, vol.58
, pp. 1143
-
-
Loughney, K.1
Kreber, R.2
Ganetzky, B.3
-
14
-
-
0025925276
-
-
K. Loughney, R. Kreber, B. Ganetzky, Cell 58, 1143 (1989); M. J. Kernan, M. I. Kuroda, R. Kreber, B. S. Baker, B. Ganetzky, ibid. 66, 949 (1991).
-
(1991)
Cell
, vol.66
, pp. 949
-
-
Kernan, M.J.1
Kuroda, M.I.2
Kreber, R.3
Baker, B.S.4
Ganetzky, B.5
-
15
-
-
0026413976
-
-
N. Atkinson, G. Robertson, B. Ganetzky, Science 253, 551 (1991); G. Feng, P. Deak, M. Chopra, L. M. Hall, Cell 82, 1001 (1995); S. A. Titus, J. W. Warmke, B. Ganetzky, J. Neurosci. 17, 875 (1997); X. Wang, E. R. Reynolds, P. Deak, L. M. Hall, ibid., p. 882.
-
(1991)
Science
, vol.253
, pp. 551
-
-
Atkinson, N.1
Robertson, G.2
Ganetzky, B.3
-
16
-
-
0029091192
-
-
N. Atkinson, G. Robertson, B. Ganetzky, Science 253, 551 (1991); G. Feng, P. Deak, M. Chopra, L. M. Hall, Cell 82, 1001 (1995); S. A. Titus, J. W. Warmke, B. Ganetzky, J. Neurosci. 17, 875 (1997); X. Wang, E. R. Reynolds, P. Deak, L. M. Hall, ibid., p. 882.
-
(1995)
Cell
, vol.82
, pp. 1001
-
-
Feng, G.1
Deak, P.2
Chopra, M.3
Hall, L.M.4
-
17
-
-
0031030547
-
-
N. Atkinson, G. Robertson, B. Ganetzky, Science 253, 551 (1991); G. Feng, P. Deak, M. Chopra, L. M. Hall, Cell 82, 1001 (1995); S. A. Titus, J. W. Warmke, B. Ganetzky, J. Neurosci. 17, 875 (1997); X. Wang, E. R. Reynolds, P. Deak, L. M. Hall, ibid., p. 882.
-
(1997)
J. Neurosci.
, vol.17
, pp. 875
-
-
Titus, S.A.1
Warmke, J.W.2
Ganetzky, B.3
-
18
-
-
0026413976
-
-
N. Atkinson, G. Robertson, B. Ganetzky, Science 253, 551 (1991); G. Feng, P. Deak, M. Chopra, L. M. Hall, Cell 82, 1001 (1995); S. A. Titus, J. W. Warmke, B. Ganetzky, J. Neurosci. 17, 875 (1997); X. Wang, E. R. Reynolds, P. Deak, L. M. Hall, ibid., p. 882.
-
J. Neurosci.
, pp. 882
-
-
Wang, X.1
Reynolds, E.R.2
Deak, P.3
Hall, L.M.4
-
19
-
-
0023664018
-
-
The stop codon is followed by a 1.9-kb untranslated tail that includes a potential polyadenylation signal
-
A single open reading frame of 5505 base pairs was found, beginning with a methionine codon preceded by a Drosophila consensus initiation sequence (AAAATG) [D. R. Cavener, Nucleic Acids Res. 15,1353 (1987)]. The stop codon is followed by a 1.9-kb untranslated tail that includes a potential polyadenylation signal.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 1353
-
-
Cavener, D.R.1
-
23
-
-
0345178426
-
-
note
-
Results from extensive polymerase chain reaction (PCR) analysis suggest that axo does not undergo any alternative splicing within the coding region. In contrast, hundreds of isoforms of mammalian neurexins, including some that are secreted, are generated by alternative splicing.
-
-
-
-
25
-
-
0001129791
-
-
M. Bate and A. M. Arias, Eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
C. S. Goodman and C. Q. Doe, in The Development of Drosophila, M. Bate and A. M. Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), p. 1131; K. Ito et al., Roux's Arch. Dev. Biol. 204, 284 (1995).
-
(1993)
The Development of Drosophila
, pp. 1131
-
-
Goodman, C.S.1
Doe, C.Q.2
-
26
-
-
0029011452
-
-
C. S. Goodman and C. Q. Doe, in The Development of Drosophila, M. Bate and A. M. Arias, Eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1993), p. 1131; K. Ito et al., Roux's Arch. Dev. Biol. 204, 284 (1995).
-
(1995)
Roux's Arch. Dev. Biol.
, vol.204
, pp. 284
-
-
Ito, K.1
-
27
-
-
0029084787
-
-
B. W. Jones, R. D. Fetter, G. Tear, C. S. Goodman, Cell 82, 1013 (1995); T. Hosoya, K. Takizawa, K. Nitta, Y. Hotta, ibid., p. 1025.
-
(1995)
Cell
, vol.82
, pp. 1013
-
-
Jones, B.W.1
Fetter, R.D.2
Tear, G.3
Goodman, C.S.4
-
28
-
-
0029084787
-
-
B. W. Jones, R. D. Fetter, G. Tear, C. S. Goodman, Cell 82, 1013 (1995); T. Hosoya, K. Takizawa, K. Nitta, Y. Hotta, ibid., p. 1025.
-
Cell
, pp. 1025
-
-
Hosoya, T.1
Takizawa, K.2
Nitta, K.3
Hotta, Y.4
-
29
-
-
0345610469
-
-
note
-
A rat polyclonal antibody was raised against a bacterially expressed fusion protein corresponding to an extracellular domain of AXO (amino acids 410 through 643). The fusion protein was generated with the QIA expression system, purified on Ni-NTA resin (Qiagen), and further gel-purified for immunizing animals. For immunostaining, primary antibody was diluted 1:250, and rabbit anti-rat immunoglobulin G was diluted 1:1000.
-
-
-
-
30
-
-
0039534396
-
-
+ found in Drosophila hemolymph
-
+ found in Drosophila hemolymph [M. Ashburner, Drosophila: A Laboratory Handbook (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989), p. 207].
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, pp. 4047
-
-
Wu, C.F.1
Ganetzky, B.2
Jan, L.Y.3
Jan, L.N.4
Benzer, S.5
-
31
-
-
0003455528
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
+ found in Drosophila hemolymph [M. Ashburner, Drosophila: A Laboratory Handbook (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989), p. 207].
-
(1989)
Drosophila: A Laboratory Handbook
, pp. 207
-
-
Ashburner, M.1
-
32
-
-
0345610467
-
-
note
-
P12-revertant larvae exposed to 38 °C for up to 20 min showed no failure of EJPs and no change in the stimulus threshold in response to a 5-Hz train (n = 8).
-
-
-
-
33
-
-
0026471340
-
-
M. Gho, K. McDonald, B. Ganetzky, W. M. Saxton, Science 258, 313 (1992).
-
(1992)
Science
, vol.258
, pp. 313
-
-
Gho, M.1
McDonald, K.2
Ganetzky, B.3
Saxton, W.M.4
-
34
-
-
0028208251
-
-
R. L. Wu and M. E. Barish, J. Neurosci. 14, 1677 (1994); M. R. Kaplan et al., Nature 386, 724 (1997).
-
(1994)
J. Neurosci.
, vol.14
, pp. 1677
-
-
Wu, R.L.1
Barish, M.E.2
-
35
-
-
0030901101
-
-
R. L. Wu and M. E. Barish, J. Neurosci. 14, 1677 (1994); M. R. Kaplan et al., Nature 386, 724 (1997).
-
(1997)
Nature
, vol.386
, pp. 724
-
-
Kaplan, M.R.1
-
36
-
-
0345178422
-
-
note
-
We thank B. Jones and C. Goodman for providing the gcm strain; R. Kreber for excellent technical help; C.-S. Hong for advice and help on the initial phase of this project; C.-F. Wu, M.-L. Chen, and M. Stern for providing help and equipment for some experiments; and T. Littleton, G. Wilson, B. Anson, and C. Kung for comments on the manuscript. Supported by grants from NIH (GM43100 and NS15390) and Wyeth-Ayerst. This is paper number 3527 from the Laboratory of Genetics, University of Wisconsin, Madison.
-
-
-
|