Determination of insulin, leptin and neuropeptide Y by radioimmunoanalysis in patients with morbid obesity and anorexia nervosa after therapeutic intervention;Determinación por radioinmunoanálisis de insulina, leptina y neuropéptido Y en pacientes con obesidad mórbida y anorexia nerviosa después de intervención terapéutica

Revista Espanola de Medicina Nuclear

Volumn 21, Issue 1, 2002, Pages 3-11

  Escobar Jimenez L ^a   Freire, J Ma ^a   Espinosa, R ^a   Pajares, M ^a   Giron J A ^a   Vazquez J M ^a   Chover, A ^b   Carrasco, M ^a   Ortego, J ^a   Gavilan I ^a   Segura, E ^a   Aguilar, M ^a  

^a HOSPITAL UNIVERSITARIO PUERTA DEL MAR   (Spain)

^b UNIVERSITY OF CÁDIZ   (Spain)

Author keywords

Anorexia nervosa; Insulin; Leptin; Morbid obesity; Neuropeptide Y; RIA

Indexed keywords

INSULIN; LEPTIN; NEUROPEPTIDE Y;

ADULT; ANOREXIA NERVOSA; ARTICLE; BODY FAT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FOLLOW UP; HORMONE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; MORBID OBESITY; RADIOIMMUNOASSAY; ANTHROPOMETRY; BLOOD; BODY COMPOSITION; DIET THERAPY; GASTROPLASTY; LOW CALORY DIET; MALE; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; RECURRENT DISEASE; WEIGHT GAIN; WEIGHT REDUCTION;

ADULT; ANOREXIA NERVOSA; ANTHROPOMETRY; BODY COMPOSITION; BODY MASS INDEX; COMBINED MODALITY THERAPY; DIET, REDUCING; FEMALE; GASTROPLASTY; HUMANS; INSULIN; LEPTIN; MALE; MIDDLE AGED; NEUROPEPTIDE Y; OBESITY, MORBID; RADIOIMMUNOASSAY; RECURRENCE; WEIGHT GAIN; WEIGHT LOSS;

EID: 0036479667     PISSN: 02126982     EISSN: 1578200X     Source Type: Journal    
DOI: 10.1016/s0212-6982(02)72025-9     Document Type: Article

References (33)

1. Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-5.
2. Freire JM, Pajares M, Escobar L, et al. Determinación por radioinmunoanálisis de leptina sérica. Resultados Preliminares. Rev. Esp. Med. Nuclear 1997;16:14-7.
3. Escobar L, Freire JM, Girón JA, et al. Niveles plasmáticos de insulina y leptina en pacientes con obesidad mórbida y anorexia nerviosa después de pérdida o ganancia de peso, respectivamente. Rev Esp Med Nuclear 2000;19:199-206.
4. Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Rohner-Jeanrenaud B. The ob gene and insulin. A relationshinp leading to clues to understanding obesity. Diabetes 1995;44:1467-70.
5. Saad MF, Khan A, Sharma A, et al. Physiological insulinemia acutely modulates plasma leptin. Diabetes 1998;47:544-9.
6. Casanueva FF, Diéguez C, Popovic V, Peino R, Considine RV, Caro JF. Serum immunoreactive leptin concentrations in patients with anorexia nervosa before and after partial weight recovery. Biochem Molec Medicine 1997;60:116-20.
7. Escobar L, Espinosa R. Regulación de la ingesta. Control del apetito. En: Moreno B, Monereo S, Álvarez J, editores. Obesidad. Epidemia del siglo XXI. Madrid: Internacional de Ediciones y Publicaciones S.A., 1999:24-38.
8. Baranowska B, Wasilewska-Dziubinska E, Radzikowska M, Plonowski A, Roguski K, Neuropeptide Y, Galanin, and leptin release in obese women and in women with anorexia nervosa. Metabolism 1997;46:1384-9.
9. th ed. Washington, D.C.: American Psychiatric Association, 1994.
10. Alastrué A, Rull M, Broggi MA. Obesidad severa y cirugía. En: Foz M, Formiguera X, editores. Obesidad. Madrid: Harcourt Brace, 1998:169-231.
11. Mason EE. Morbid obesity: use of vertical banded gastroplasty. Surg Clin North Am 1987;67:521-37.
12. Friedman JM, Halaas JL. Leptin ans the regulation of body weight in mammals. Nature 1998;395:763-70.
13. Caro JF, Kolaczynski JW, Nyce MR, et al. Decreased cerebrospinal-fluid/ serum leptin ratio in obesity: a possible mechanism for leptin resistance. Lancet 1996;348:159-61.
14. Karonen S, Koistinen HA, Nikkinen P, Koivisto VA. Is brain uptake of leptin in vivo saturable and reduced by fasting. Eur J Nucl Med 1998;25:607-12.
15. Ahima RSN Prabakaran D, Mantzoros C, et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996;382:250-2.
16. Schwartz MW, Seeley RJ. Neuroendocrine response to starvation and weight loss. N Engl J Med 1997;336:1802-11.
17. Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte D. Insulin in the brain: a hormonal regulator of energy balance. Endocrine Reviews 1992;13:387-414.
18. Schwartz MW, Sipols AJ, Marks JL, et al. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Edocrinology 1992;130:3608-16.
19. Saladin R, De Vos P, Guerre-Millo M, et al. Transient increase in obese gene expression after food intake or insulin administration. Nature 1995; 377:527-9.
20. Toornvliet AC, Pijl H, Frölich M, Westendorp RGJ, Meinders AE. Insulin and leptin concentrations in obese humans during long-term weight loss. Netherlands Journal of Medicine 1997;51:96-102.
21. Zukowska-Grojek Z. Neuropeptide Y: a novel sympathetic stress hormone and more. Ann N Y Acad Sci 1995;771:219-33.
22. Takahashi K, Mouri T, Murakami O, et al. Increases of neuropeptide Y-like inmunoreactivity inplasma during insulin-induced hypoglycemia in man. Peptides 1988;9:433-5.
23. Dyer C, Simmons J, Matteri R, Keisler D. Effects of an intravenous injection of NPY on leptin and NPY-Y1 receptor mRNA expression in ovine adipose tissue. Domestic animal endocrinology 1997;14:325-33.
24. Banks WA, Kastin AJ, Huang W. Leptin enters the brain by a saturable system independent of insulin. Peptides 1996;17:305-11.
25. Kastin A, Akerstrom V. Nonsaturable entry of neuropeptide Y into brain. Am J Physiol 1999;276:E479-82.
26. Gray TS, Morley JE. Neuropeptide Y: anatomical distribution and possible function in mammalian nervous system. Life Sci 1986;38:389-401.
27. Bennet W, Wangz, Jones P, et al. Presence of neuropeptide Y and its messenger ribonucleic acid in human islets: evidence for a possible paracrine role. J Clin Endocrinol Metab 1996;81:2117-20.
28. Vettor R, Pagano C, Granzotto M, et al. Effects of intravenous neuropeptide Y on insulin secretion and insulin sensitivity in skeletal muscle in normal rats. Diabetologia 1998;41:1361-7.
29. Rosenbaum M, Leibel R. The role of leptin in human physiology. N Eng J Med 1999;341:913-5.
30. Schwartz M, Seeley R. Neuroendocrine responses to starvation and weight loss. N Eng J Med 1997;336:1802-11.
31. Eckert E, Pomeroy C, Raymond N, Kohler P, Thuras P, Bowers C. Leptin in Anorexia Nervosa. J Clin Endoc Metab 1998;83:791-5.
32. Himes JH. Reliability of anthropometric methods and replicate measurements. Am J Phys Anthropol 1989;79: 77-80.
33. Formiguera X. Obesidad: concepto, clasificación y métodos de valoración. En: «Obesidad». FOZ M, FORMIGUERA X (eds.). Harcourt Brace 1998. Madrid: 1-23.