NMDA receptors and PSD-95 are found in attachment plaques in cerebellar granular layer glomeruli

European Journal of Neuroscience

Volumn 15, Issue 3, 2002, Pages 583-587

  Petralia, Ronald S ^a   Wang, Ya Xian ^a   Wenthold, Robert J ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

AMPA; Cadherin; Catenin; Contactus adherens; Puncta adherentia

Indexed keywords

AMPA RECEPTOR; AMPA RECEPTOR ANTIBODY; CADHERIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PSD 95; RECEPTOR ANTIBODY; RECEPTOR PROTEIN; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; GRANULAR CELL; IMMUNOASSAY; MOUSE; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SYNAPSE;

ADHERENS JUNCTIONS; ANIMALS; CADHERINS; CELL ADHESION; CEREBELLAR CORTEX; DENDRITES; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICROSCOPY, ELECTRON; NERVE TISSUE PROTEINS; PRESYNAPTIC TERMINALS; RATS; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTIC MEMBRANES;

EID: 0036458644     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.01896.x     Document Type: Article

References (43)

1. Akazawa, C., Shigemoto, R., Bessho, Y., Nakanishi S. & Mizuno, N. (1994) Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J. Comp. Neurol., 347, 150-160.
2. Armano, S., Rossi, P., Taglietti, V. & D'Angelo, E. (2000) Long-term potentiation of intrinsic excitability at the mossy fiber-granule cell synapse of rat cerebellum. J. Neurosci., 20, 5208-5216.
3. Bahjaoui-Bouhaddi, M., Padilla, F., Nicolet, M., Cifuentes-Diaz, C., Fellmann, D. & Mege, R.M. (1997) Localized deposition of M-cadherin in the glomeruli of the granular layer during the postnatal development of mouse cerebellum. J. Comp. Neurol., 378, 180-195.
4. Blahos, J. II & Wenthold, R.J. (1996) Relationship between N-methyl-D-aspartate receptor NR1 splice variants and NR2 subunits. J. Biol. Chem., 271, 15669-15674.
5. Chen, L., Chetkovich, D.M., Petralia, R.S., Sweeney, N.T., Kawasaki, Y., Wenthold, R.J., Bredt, D.S. & Nicoll, R.A. (2000) Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature, 408, 936-943.
6. DiGregorio, D.A. & Silver, R.A. (2001) Glutamate spillover onto AMPA receptors contributes to fast transmission at cerebellar mossy fiber-granule cell synapses. Soc. Neurosci. Abstr. 27, 155.1.
7. Dingledine, R., Borges, K., Bowie, D. & Traynelis, S.F. (1999) The glutamate receptor ion channels. Pharm. Rev., 51, 7-61.
8. Hámori, J., Jakab, R.I. & Takács, J. (1997) Morphogenetic plasticity of neuronal elements in cerebellar glomeruli during deafferentation-induced synaptic reorganization. J. Neural Transplant Plast., 6, 11-20.
9. Honjo, Y., Nakagawa, S. & Takeichi, M. (2000) Blockade of cadherin-6B activity perturbs the distribution of PSD-95 family proteins in retinal neurones. Genes Cells, 5, 309-318.
10. Huh, K.-H. & Wenthold, R.J. (1999) Turnover analysis of glutamate receptors identifies a rapidly degraded pool of the N-methyl-D-aspartate receptor subunit, NR1, in cultured cerebellar granule cells. J. Biol. Chem., 274, 151-157.
11. Husi, H., Ward, M.A., Choudhary, J.S., Blackstock, W.P. & Grant, S.G.N. (2000) Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nature Neurosci., 3, 661-669.
12. Luo, J., Wang, Y., Yasuda, R.P., Dunah, A.W. & Wolfe. B.B. (1997) The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B). Mol. Pharmacol. 51, 79-86.
13. McGee, A.W., Topinka, J.R., Hashimoto, K., Petralia, R.S., Kakizawa, S., Kauer, F., Aguilera-Moreno, A., Wenthold, R.J., Kano, M. & Bredt, D.S. (2001) PSD-93 knock-out mice reveal that neuronal MAGUKs are not required for development or function of parallel fiber synapses in cerebellum. J. Neurosci., 21, 3085-3091.
14. Merighi, A. (1992) Post-embedding electron microscopic immunocyto-chemistry. In Polak, J.M. & Priestley, J.V. (eds), Electron Microscopic Immunocytochemistry: Principles and Practice. Oxford University Press, New York, pp. 51-87.
15. Mitchell, S.J. & Silver, R.A. (2000) Glutamate spillover suppresses inhibition by activating presynaptic mGluRs. Nature, 404, 498-502.
16. Mugnaini, E. (1972) The histology and cytology of the cerebellar cortex. In Larsell, O. & Jansen, J. (eds), The Comparative Anatomy and Histology of the Cerebellum. University Minnesota Press, Minneapolis, pp. 201-264.
17. Nishimura, W., Iizuka, T., Hirabayashi, S., Tanaka, N. & Hata, Y. (2000) Localization of BAI-associated protein 1/membrane-associated guanylate kinase-1 at adherens junctions in normal rat kidney cells: Polarized targeting mediated by the carboxyl-terminal PDZ domains. J. Cell. Physiol., 185, 358-365.
18. Ohishi, H., Ogawa-Meguro, R., Shigemoto, R., Kaneko, T., Nakanishi, S. & Mizuno, N. (1994) Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex. Neuron, 13, 55-66.
19. Palay, S. & Chan-Palay, V. (1974) Cerebellar cortex. Cytology and Organization. Springer, New York.
20. Perego, C., Vanoni, C., Massari, S., Longhi, R. & Pietrini, G. (2000) Mammalian LIN-7 PDZ proteins associate with β-catenin at the cell-cell junctions of epithelia and neurons. EMBO J., 19, 3978-3989.
21. Petralia, R.S., Esteban, J.A., Wang, Y.-X., Partridge, J.G., Zhao, H.-M. & Wenthold, R.J. (1999) Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses. Nature Neurosci., 2, 31-36.
22. Petralia, R.S., Rubio, M.E., Wang, Y.-X. & Wenthold, R.J. (2000) Regional and synaptic expression of ionotropic glutamate receptors. In Ottersen, O.P. & Storm-Mathisen, J. (eds), Handbook of Chemical Neuroanatomy: Glutamate. Elsevier Science, New York, pp. 145-182.
23. Petralia, R.S., Wang, Y.-X., Sans, N., Worley, P.F., Hammer, J.A. III & Wenthold, R.J. (2001a) Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va. Eur. J. Neurosci., 13, 1722-1732.
24. Petralia, R.S., Sans, N., Vissel, B., Wang, Y.-X., Royle, G.A., Noben-Trauth, K., Heinemann. S.F. & Wenthold, R.J. (2001b) Distribution of glutamate receptors in mice lacking the AMPA receptor subunit, GluR2. Soc. Neurosci. Abstr. 27, 481.7.
25. Petralia, R.S. & Wenthold, R.J. (1992) Light and electron immunocytochemical localization of AMPA-selective glutamate receptors in the rat brain. J. Comp. Neurol., 318, 329-354.
26. Petralia, R.S. & Wenthold, R.J. (1999) Immunocytochemistry of NMDA receptors. In Li, M. (ed.), Methods in Molecular Biology: NMDA Receptor Protocols. Humana Press, Totowa, NJ.
27. Petralia, R.S., Yokotani, N. & Wenthold, R.J. (1994a) Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci., 14, 667-696.
28. Petralia, R.S., Wang, Y.-X. & Wenthold, R.J. (1994b) The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J. Neurosci., 14, 6102-6120.
29. Prybylowski, K., Rumbaugh, G., Wolfe B.B. & Vicini, S. (2000) Increased exon 5 expression alters extrasynaptic NMDA receptors in cerebellar neurons. J. Neurochem. 75, 1140-1146.
30. Reuver, S.M. & Garner, C.C. (1998) E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeleton. J. Cell Sci., 111, 1071-1080.
31. Rose, O., Grund, C., Reinhardt, S., Starzinski-Powitz, A. & Franke, W.W. (1995) Contactus adherens, a special type of plaque-bearing adhering junction containing M-cadherin, in the granule cell layer of the cerebellar glomerulus. Proc. Natl. Acad. Sci. USA, 92, 6022-6026.
32. Rusakov, D.A., Kullmann, D.M. & Stewart, M.G. (1999) Hippocampus synapses: Do they talk to their neighbours? Trends Neurosci., 22, 382-388.
33. Sans, N., Petralia, R.S., Wang, Y.-X., Blahos, J. II, Hell, J.W. & Wenthold, R.J. (2000) A developmental change in NMDA receptor-associated proteins at hippocampal synapses. J. Neurosci., 20, 1260-1271.
34. Schoppa, N.E. & Westbrook, G.L. (2001) Glomerulus-specific synchronization of mitral cells in the olfactory bulb. Neuron, 31, 639-651.
35. Sheng, M. & Sala, C. (2001) PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci., 24, 1-29.
36. Sucher, N.J. Brose, N. Deitcher, D.L. Awobuluyi, M. Gasic, G.P. Bading, H. Cepko, C.L. Greenberg, M.E. Jahn, R. Heinemann. S.F. Lipton, S.A. (1993) Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-translational control of PC12 cells. J. Biol. Chem., 268, 22299-22304.
37. Tanaka, H. Shan, W. Phillips, G.R. Arndt, K. Bozdagi, O. Shapiro, L. Huntley, G.W. Benson, D.L. & Colman, D.R. (2000) Molecular modification of N-cadherin in response to synaptic activity. Neuron, 25, 93-107.
38. Tang, L. Hung, C.P. & Schuman, E.M. (1998) A role for the cadherin family of cell adhesion molecules in hippocampal long-term potentiation. Neuron, 20, 1165-1175.
39. Tomita, S. . Nicoll, R.A. & Bredt, D.S. (2001) PDZ protein interactions regulating glutamate receptor function and plasticity. J. Cell Biol., 153, F19-F23.
40. Watanabe, M. Mishina, M. & Inoue, Y. (1994) Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum. J. Comp. Neurol., 343, 513-519.
41. Wenthold, R.J. Yokotani, N. Doi, K. & Wada, K. (1992) Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. J. Biol. Chem., 267, 501-507.
42. Yamada, K. Fukaya, M. Shimizu, H. Sakimura, K. & Watanabe, M. (2001) NMDA receptor subunits GluRe1, GluRe3 and GluRz1 are enriched at the mossy fibre-granule cell synapse in the adult mouse cerebellum. Eur. J. Neurosci., 13, 2025-2036.
43. Ziff, E.B. (1997) Enlightening the postsynaptic density. Neuron, 19, 1163-1174.