Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va

European Journal of Neuroscience

Volumn 13, Issue 9, 2001, Pages 1722-1732

  Petralia, Ronald S ^a   Wang, Ya Xian ^a   Sans, Nathalie ^a   Worley, Paul F ^b   Hammer III, John A ^c   Wenthold, Robert J ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

AMPA; Cerebellum; Delta; dilute mouse; Rat

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM; DYNEIN ADENOSINE TRIPHOSPHATASE; GLUTAMATE RECEPTOR; GUANYLATE KINASE; INOSITOL TRISPHOSPHATE; MYOSIN;

ANIMAL TISSUE; ARTICLE; CEREBELLUM CORTEX; CONTROLLED STUDY; CYTOSKELETON; DENDRITE; DIFFUSION; IMMUNOGOLD STAINING; LETHAL MUTANT; LONG TERM POTENTIATION; MOUSE; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN TARGETING; PROTEIN TRANSPORT; RAT; RECEPTOR UPREGULATION;

ACTINS; ANIMALS; CALCIUM CHANNELS; CARRIER PROTEINS; CEREBELLAR CORTEX; DENDRITES; DROSOPHILA PROTEINS; GUANYLATE KINASE; HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, MUTANT STRAINS; MICROSCOPY, ELECTRON; MOLECULAR CHAPERONES; MYOSINS; NEUROPEPTIDES; NUCLEOSIDE-PHOSPHATE KINASE; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, GLUTAMATE; SYNAPTIC MEMBRANES;

EID: 0035015910     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01553.x     Document Type: Article

References (54)

1. Adam, G. & Matus, A. (1996) Role of actin in the organisation of brain postsynaptic densities. Mol. Brain Res., 43, 246-250.
2. Allison, D.W., Gelfand, V.I., Spector, I. & Craig, A.M. (1998) Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors. J. Neurosci., 18, 2423-2436.
3. Altman, J. & Bayer, S.A. (1997) Development of the Cerebellar System. CRC Press, New York, NY.
4. Baude, A., Nusser, Z., Roberts, J.D.B., Mulvihill, E., McIlhinney, R.A.J. & Somogyi, P. (1993) The metabotropic glutamate receptor (mGluR1α) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron, 11, 771-787.
5. Bridgman, P.C. (1999) Myosin Va movements in normal and dilute-lethal axons provide support for a dual filament motor complex. J. Cell. Biol., 146, 1045-1060.
6. Bruneau, N., Lombardo, D., Levy, E. & Bendayan, M. (2000) Roles of molecular chaperones in pancreatic secretion and their involvement in intestinal absorption. Microsc. Res. Tech., 49, 329-345.
7. Dekker-Ohno, K., Hayasaka, S., Takagishi, Y., Oda, S., Wakasugi, N., Mikoshiba, K., Inouye, M. & Yamamura, H. (1996) Endoplasmic reticulum is missing in dendritic spines of Purkinje cells of the ataxic mutant rat. Brain Res., 714, 226-230.
8. Espreafico, E.M., Cheney, R.E., Matteoli, M., Nascimento, A.A.C., De Camilli, P.V., Larson, R.E. & Mooseker, M.S. (1992) Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains. J. Cell Biol., 119, 1541-1557.
9. Evans, L.L., Hammer, J. & Bridgman, P.C. (1997) Subcellular localization of myosin V in nerve growth cones and outgrowth from dilute-lethal neurons. J. Cell Sci., 110, 439-449.
10. Fifková, E. & Morales, M. (1992) Actin matrix of dendritic spines, synaptic plasticity, and long-term potentiation. Int. Rev. Cytol., 139, 267-307.
11. Fischer, M., Kaech, S., Knutti, D. & Matus, A. (1998) Rapid actin-based plasticity in dendritic spines. Neuron, 20, 847-854.
12. Fischer, M., Kaech, S., Wagner, U., Brinkhaus, H. & Matus, A. (2000) Glutamate receptors regulate actin-based plasticity in dendritic spines. Nature Neurosci., 3, 887-894.
13. Garner, C.C., Nash, J. & Huganir, R.L. (2000) PDZ domains in synapse assembly and signalling. Trends Cell Biol., 10, 274-280.
14. Halpain, S., Hipolito, A. & Saffer, L. (1998) Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J. Neurosci., 18, 9835-9844.
15. Kim, C.-H. & Lisman, J.E. (1999) A role of actin filament in synaptic transmission and long-term potentiation. J. Neurosci., 19, 4314-4324.
16. Landsend, A.S., Amiry-Moghaddam, M., Matsubara, A., Bergersen, L., Usami, S., Wenthold, R.J. & Ottersen, O.P. (1997) Differential localization of δ glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses. J. Neurosci., 17, 834-842.
17. Langford, G.M. & Molyneaux, B.J. (1998) Myosin V in the brain: mutations lead to neurological defects. Brain Res. Rev., 28, 1-8.
18. Matsubara, A., Laake, J.H., Davanger, S., Usami, S. & Ottersen, O.P. (1996) Organization of AMPA receptor subunits at a glutamate synapse: a quantitative immunogold analysis of hair cell synapses in the rat organ of Corti. J. Neurosci., 16, 4437-4467.
19. Mayat, E., Petralia, R.S., Wang, Y.-X. & Wenthold, R.J. (1995) Immunoprecipitation, immunoblotting and immunocytochemistry studies suggest that glutamate receptor delta subunits form novel postsynaptic receptor complexes. J. Neurosci., 15, 2533-2546.
20. Mercer, J.A., Seperack, P.K., Strobel, M.C., Copeland, N.G. & Jenlcins, N.A. (1991) Novel myosin heavy chain encoded by murine dilute coat colour locus. Nature, 349, 709-713.
21. Morales, M. & Fifková, E. (1989) In situ localization of myosin and actin in dendritic spines with the immunogold technique. J. Comp. Neurol., 279, 666-674.
22. Naisbitt, S., Valtschanoff, J., Allison, D.W., Sala, C., Kim, E., Craig, A.M., Weinberg, R.J. & Sheng, M. (2000) Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein. J. Neurosci., 20, 4524-4534.
23. Pavlik, L.L. & Moshkov, D.A. (1992) Actin in synaptic cytoskeleton during long-term potentiation in hippocampal slices. Acta Hist., (Suppl. XLI), 257-264.
24. Petralia, R.S., Esteban, J.A., Wang, Y.-X., Partridge, J.G., Zhao, H.-M., Wenthold, R.J. & Malinow, R. (1999a) Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses. Nature Neurosci., 2, 31-36.
25. Petralia, R.S., Rubio, M.E., Wang, Y.-X. & Wenthold, R.J. (2000) Regional and synaptic expression of ionotropic glutamate receptors. In Ottersen, O.P., Storm-Mathisen, J. (eds), Handbook of Chemical Neuroanatomy: Glutamate. Elsevier Science, New York, NY, pp. 145-182.
26. Petralia, R.S., Rubio, M.E., & Wenthold, R.J. (1999b) Cellular and subcellular distribution of glutamate receptors. In Jonas, P., Monyer, H. (eds), Handbook of Experimental Pharmacology: Ionotropic Glutamate Receptors in the CNS. Springer-Verlag, New York, NY, pp. 143-171.
27. Petralia, R.S., Wang, Y.-X., Sans, N. & Wenthold, R.J. (1999c) Organization of glutamate receptors and associated proteins in the postsynaptic spine. Soc. Neurosci. Abstr., 25, 1237.
28. Petralia, R.S., Wang, Y.-X., Singh, S., Wu, C., Shi, L., Wei, J. & Wenthold, R.J. (1997) A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1α metabotropic glutamate receptors. J. Chem. Neuroanat., 13, 77-93.
29. Petralia, R.S. & Wenthold, R.J. (1998) Glutamate receptors: Synthetic peptides and histochemical analysis. In Ariano, M.A. (ed.), Receptor Localization: Laboratory Methods and Procedures. Wiley, New York, NY, pp. 46-74.
30. Petralia, R.S. & Wenthold, R.J. (1999) Immunocytochemistry of NMDA receptors. In Li, M. (ed.), Methods in Molecular Biology: NMDA Receptor Protocols. Humana Press, Totowa, NJ, pp. 73-92.
31. Petralia, R.S., Zhao, H.-M., Wang, Y.-X. & Wenthold, R.J. (1998) Variations in the tangential distribution of postsynaptic glutamate receptors in Purkinje cell parallel and climbing fiber synapses during development. Neuropharmacology, 37, 1321-1334.
32. Roche, K.W., Ly, C.D., Petralia, R.S., Wang, Y.-X., McGee, A.W., Bredt, D.S. & Wenthold, R.J. (1999a) Postsynaptic density-93 interacts with the δ2 glutamate receptor subunit at parallel fiber synapses. J. Neurosci., 19, 3926-3934.
33. Roche, K.W., Tu, J.C., Petralia, R.S., Xiao, B., Wenthold, R.J. & Worley, P.F. (1999b) Homer 1b regulates the trafficking of group I metabotropic glutamate receptors. J. Biol. Chem., 274, 25953-25957.
34. van Rossum, D. & Hanisch, U.-K. (1999) Cytoskeletal dynamics in dendritic spines: direct modulation by glutamate receptors? Trends Neurosci., 22, 290-295.
35. Rubio, M.E. & Wenthold, R.J. (1999a) Differential distribution of intracellular glutamate receptors in dendrites. J. Neurosci., 19, 5549-5562.
36. Rubio, M.E. & Wenthold, R.J. (1999b) Calnexin and the immunoglobulin binding protein (BiP) coimmunoprecipitate with AMPA receptors. J. Neurochem., 73, 942-948.
37. Sans, N., Petralia, R.S., Wang, Y.-X., Blahos, J. II., Hell, J.W. & Wenthold, R.J. (2000) A developmental change in NMDA receptor-associated proteins at hippocampal synapses. J. Neurosci., 20, 1260-1271.
38. Setou, M., Nakagawa, T., Seog, D.-H. & Hirokawa, N. (2000) Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science, 288, 1796-1802.
39. Spacek, J. & Harris, K.M. (1997) Three-dimensional organization of smooth endoplasmic reticulum in hippocampal CA1 dendrites and dendritic spines of the immature and mature rat. J. Neurosci., 17, 190-203.
40. Tabb, J.S., Molyneaux, B.J., Cohen, D.L., Kuznetsov, S.A. & Langford, G.M. (1998) Transport of ER vesicles on actin filaments in neurons by myosin V. J. Cell Sci., 111, 3221-3234.
41. 2+ store in the dendritic spine of Purkinje cells in mice. Neurosci. Lett., 215, 169-172.
42. Takayama, C., Nakagawa, S., Watanabe, M., Mishina, M. & Inoue, Y. (1996) Developmental changes in expression and distribution of the glutamate receptor channel δ2 subunit according to the Purkinje cell maturation. Dev. Brain Res., 92, 147-155.
43. Tarrant, S.B. & Routtenberg, A. (1979) Postsynaptic membrane and spine apparatus: Proximity in dendritic spines. Neurosci. Lett., 11, 289-294.
44. Tatsuoka, H. & Reese, T.S. (1989) New structural features of synapses in the anteroventral cochlear nucleus prepared by direct freezing and freeze-substitution. J. Comp. Neurol., 290, 343-357.
45. Tu, J.C., Xiao, B., Yuan, J.P., Lanahan, A.A., Leoffert, K., Li, M., Linden, D.J. & Worley, P.F. (1998) Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron, 21, 717-726.
46. Walikonis, R.S., Jensen, O.N., Mann, M., Provance, D.W. Jr, Mercer, J.A. & Kennedy, M.B. (2000) Identification of proteins in the postsynaptic density fraction by mass spectrometry. J. Neurosci., 20, 4069-4080.
47. Wenthold, R.J., Yokotani, N., Doi, K. & Wada, K. (1992) Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. Evidence for a hetero-oligomeric structure in rat brain. J. Biol. Chem., 267, 501-507.
48. Wu, X., Bowers, B., Wei, Q., Kocher, B. & Hammer, J. A. III (1997) Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor. J. Cell Sci., 110, 847-859.
49. Wu, X., Jung, G. & Hammer, J.A. III (2000) Functions of unconventional myosins. Curr. Opin. Cell Biol., 12, 42-51.
50. Xiao, B., Tu, J.C., Petralia, R.S., Yuan, J., Breder, C., Lanahan, A.A., Wenthold, R.J. & Worley, P.F. (1998) A family of Homer-related genes: Localization and binding properties indicate role in post synaptic functions. Neuron, 21, 707-716.
51. Xiao, B., Tu, J.C. & Worley, P.F. (2000) Homer: a link between neural activity and glutamate receptor function. Curr. Opin. Neurobiol., 10, 370-374.
52. Xie, X., Liaw, J.-S., Baudry, M. & Berger, T.W. (1997) Novel expression mechanism for synaptic potentiation: alignment of presynaptic release site and postsynaptic receptor. Proc. Natl. Acad. Sci. USA, 94, 6983-6988.
53. Zhao, L.-P., Koslovsky, J.S., Reinhard, J., Bähler, M., Witt, A.E., Provance, D.W. Jr & Mercer, J.A. (1996) Cloning and characterization of myr 6, an unconventional myosin of the dilute/myosin-V family. Proc. Natl. Acad. Sci. USA, 93, 10826-10831.
54. Zhao, H.-M., Wenthold, R.J. & Petralia, R.S. (1998) Glutamate receptor targeting to synaptic populations on Purkinje cells is developmentally regulated. J. Neurosci., 18, 5517-5528.