-
1
-
-
0032478820
-
Role of reactive oxygen intermediates in activation-induced CD95 (APO- 1/Fas) ligand expression
-
M.K. Bauer, M. Vogt, M. Los, J. Siegel, S. Wesselborg, K. Schulze-Osthoff, Role of reactive oxygen intermediates in activation-induced CD95 (APO- 1/Fas) ligand expression, J. Biol. Chem. 273 (1998) 8048-8055.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8048-8055
-
-
Bauer, M.K.1
Vogt, M.2
Los, M.3
Siegel, J.4
Wesselborg, S.5
Schulze-Osthoff, K.6
-
2
-
-
0024197767
-
Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes
-
D.A. Carson, C.J. Carrera, D.B. Wasson, H. Yamanaka, Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes, Adv. Enzyme Regul. 27 (1988) 395-404.
-
(1988)
Adv. Enzyme Regul.
, vol.27
, pp. 395-404
-
-
Carson, D.A.1
Carrera, C.J.2
Wasson, D.B.3
Yamanaka, H.4
-
3
-
-
0037079699
-
Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release
-
J. Chandra, E. Mansson, V. Gogvadze, S.H. Kaufmann, F. Albertioni, S. Orrenius, Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release, Blood 99 (2002) 655-663.
-
(2002)
Blood
, vol.99
, pp. 655-663
-
-
Chandra, J.1
Mansson, E.2
Gogvadze, V.3
Kaufmann, S.H.4
Albertioni, F.5
Orrenius, S.6
-
4
-
-
0034794745
-
Dual mechanisms of 9-β-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells
-
S. Curbo, C. Zhu, M. Johansson, J. Balzarini, A. Karlsson, Dual mechanisms of 9-β-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells, Biochem. Biophys. Res. Commun. 285 (2001) 40-45.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.285
, pp. 40-45
-
-
Curbo, S.1
Zhu, C.2
Johansson, M.3
Balzarini, J.4
Karlsson, A.5
-
5
-
-
0029935682
-
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
C. Friesen, I. Herr, P.H. Krammer, K.M. Debatin, Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells, Nat. Med. 2 (1996) 574-577.
-
(1996)
Nat. Med.
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
6
-
-
0031792644
-
Compound GW506U78 in refractory hematologic malignancies: Relationship between cellular pharmacokinetics and clinical response
-
V. Gandhi, W. Plunkett, C.O. Rodriguez Jr., B.J. Nowak, M. Du, M. Ayres, D.F. Kisor, B.S. Mitchell, J. Kurtzberg, M.J. Keating, Compound GW506U78 in refractory hematologic malignancies: Relationship between cellular pharmacokinetics and clinical response, J. Clin. Oncol. 16 (1998) 3607-3615.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 3607-3615
-
-
Gandhi, V.1
Plunkett, W.2
Rodriguez C.O., Jr.3
Nowak, B.J.4
Du, M.5
Ayres, M.6
Kisor, D.F.7
Mitchell, B.S.8
Kurtzberg, J.9
Keating, M.J.10
-
7
-
-
0034614551
-
Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway
-
D. Genini, I. Budihardjo, W. Plunkett, X. Wang, C.J. Carrera, H.B. Cottam, D.A. Carson, L.M. Leoni, Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway, J. Biol. Chem. 275 (2000) 29-34.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29-34
-
-
Genini, D.1
Budihardjo, I.2
Plunkett, W.3
Wang, X.4
Carrera, C.J.5
Cottam, H.B.6
Carson, D.A.7
Leoni, L.M.8
-
8
-
-
0032528118
-
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction, and apoptosis
-
A. Gross, J. Jockel, M.C. Wei, S.J. Korsmeyer, Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction, and apoptosis, EMBO J. 17 (1998) 3878-3885.
-
(1998)
EMBO J.
, vol.17
, pp. 3878-3885
-
-
Gross, A.1
Jockel, J.2
Wei, M.C.3
Korsmeyer, S.J.4
-
9
-
-
0029150180
-
High molecular weight DNA fragmentation: A critical event in nucleoside analogue-induced apoptosis in leukemia cells
-
P. Huang, L.E. Robertson, S. Wright, W. Plunkett, High molecular weight DNA fragmentation: A critical event in nucleoside analogue-induced apoptosis in leukemia cells, Clin. Cancer Res. 1 (1995) 1005-1013.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1005-1013
-
-
Huang, P.1
Robertson, L.E.2
Wright, S.3
Plunkett, W.4
-
10
-
-
0035968324
-
Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase
-
M. Jullig, S. Eriksson, Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase, J. Biol. Chem. 276 (2001) 24000-24004.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24000-24004
-
-
Jullig, M.1
Eriksson, S.2
-
11
-
-
0033999960
-
Pharmacokinetics of nelarabine and 9-β-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies
-
D.F. Kisor, W. Plunkett, J. Kurtzberg, B. Mitchell, J.P. Hodge, T. Ernst, M.J. Keating, V. Gandhi, Pharmacokinetics of nelarabine and 9-β-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies, J. Clin. Oncol. 18 (2000) 995-1003.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 995-1003
-
-
Kisor, D.F.1
Plunkett, W.2
Kurtzberg, J.3
Mitchell, B.4
Hodge, J.P.5
Ernst, T.6
Keating, M.J.7
Gandhi, V.8
-
12
-
-
0032483010
-
Induction of an apoptotic program in cell-free extracts by 2-chloro-2′- deoxy-adenosine 5′-triphosphate and cytochrome c
-
L.M. Leoni, Q. Chao, H.B. Cottam, D. Genini, M. Rosenbach, C.J. Carrera, I. Budihardjo, X. Wang, D.A. Carson, Induction of an apoptotic program in cell-free extracts by 2-chloro-2′- deoxy-adenosine 5′-triphosphate and cytochrome c, Proc. Natl. Acad. Sci. USA 95 (1998) 9567-9571.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9567-9571
-
-
Leoni, L.M.1
Chao, Q.2
Cottam, H.B.3
Genini, D.4
Rosenbach, M.5
Carrera, C.J.6
Budihardjo, I.7
Wang, X.8
Carson, D.A.9
-
13
-
-
0036076401
-
Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-β-D-arabinofuranosylguanine cytotoxicity
-
K. Lotfi, E. Mansson, C. Peterson, S. Eriksson, F. Albertioni, Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-β-D-arabinofuranosylguanine cytotoxicity, Biochem. Biophys. Res. Commun. 293 (2002) 1489-1496.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 1489-1496
-
-
Lotfi, K.1
Mansson, E.2
Peterson, C.3
Eriksson, S.4
Albertioni, F.5
-
14
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
X. Luo, I. Budihardjo, H. Zou, C. Slaughter, X. Wang, Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors, Cell 94 (1998) 481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
15
-
-
0035503898
-
Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria
-
I. Marzo, P. Perez-Galan, P. Giraldo, D. Rubio-Felix, A. Anel, J. Naval, Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria, Biochem. J. 359 (2001) 537-546.
-
(2001)
Biochem. J.
, vol.359
, pp. 537-546
-
-
Marzo, I.1
Perez-Galan, P.2
Giraldo, P.3
Rubio-Felix, D.4
Anel, A.5
Naval, J.6
-
16
-
-
0033054992
-
DNA damage signals induction of fas ligand in tumor cells
-
Y.Y. Mo, W.T. Beck, DNA damage signals induction of fas ligand in tumor cells, Mol. Pharmacol. 55 (1999) 216-222.
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 216-222
-
-
Mo, Y.Y.1
Beck, W.T.2
-
17
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
D.W. Nicholson, A. Ali, N.A. Thornberry, J.P. Vaillancourt, C.K. Ding, M. Gallant, Y. Gareau, P.R. Griffin, M. Labelle, Y.A. Lazebnik, et al., Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis, Nature 376 (1995) 37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
18
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
I. Nicoletti, G. Migliorati, M.C. Pagliacci, F. Grignani, C. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry, J. Immunol. Methods 139 (1991) 271-279.
-
(1991)
J. Immunol. Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
19
-
-
0033951610
-
2-Chloro-2′-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4
-
Y. Nomura, O. Inanami, K. Takahashi, A. Matsuda, M. Kuwabara, 2-Chloro-2′-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4, Leukemia 14 (2000) 299-306.
-
(2000)
Leukemia
, vol.14
, pp. 299-306
-
-
Nomura, Y.1
Inanami, O.2
Takahashi, K.3
Matsuda, A.4
Kuwabara, M.5
-
20
-
-
0002943076
-
Synthesis of 9-β-D-arabinofuranosylguanine
-
E.J. Reist, L. Goodman, Synthesis of 9-β-D-arabinofuranosylguanine, Biochemistry 3 (1964) 15-18.
-
(1964)
Biochemistry
, vol.3
, pp. 15-18
-
-
Reist, E.J.1
Goodman, L.2
-
21
-
-
1842373912
-
Pharmacological and biochemical strategies to increase the accumulation of arabinofuranosylguanine triphosphatein primary human leukemia cells
-
C.O. Rodriguez Jr., J.K. Legha, E. Estey, M.J. Keating, V. Gandhi, Pharmacological and biochemical strategies to increase the accumulation of arabinofuranosylguanine triphosphatein primary human leukemia cells, Clin. Cancer Res. 3 (1997) 2107-2113.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 2107-2113
-
-
Rodriguez C.O., Jr.1
Legha, J.K.2
Estey, E.3
Keating, M.J.4
Gandhi, V.5
-
22
-
-
0345363112
-
Arabinosylguanine-induced apoptosis of T-lymphoblastic cells: Incorporation into DNA is a necessary step
-
C.O. Rodriguez Jr., V. Gandhi, Arabinosylguanine-induced apoptosis of T-lymphoblastic cells: Incorporation into DNA is a necessary step, Cancer Res. 59 (1999) 4937-4943.
-
(1999)
Cancer Res.
, vol.59
, pp. 4937-4943
-
-
Rodriguez C.O., Jr.1
Gandhi, V.2
-
23
-
-
0036606777
-
Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase
-
C.O. Rodriguez Jr., B.S. Mitchell, M. Ayres, S. Eriksson, V. Gandhi, Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase, Cancer Res. 62 (2002) 3100-3105.
-
(2002)
Cancer Res.
, vol.62
, pp. 3100-3105
-
-
Rodriguez C.O., Jr.1
Mitchell, B.S.2
Ayres, M.3
Eriksson, S.4
Gandhi, V.5
-
24
-
-
0022459735
-
Characterization of arabinosylguanine resistance in a lymphoblastoid cell line
-
D.S. Shewach, B.S. Mitchell, Characterization of arabinosylguanine resistance in a lymphoblastoid cell line, Adv. Exp. Med. Biol. 195 (1986) 605-609.
-
(1986)
Adv. Exp. Med. Biol.
, vol.195
, pp. 605-609
-
-
Shewach, D.S.1
Mitchell, B.S.2
-
25
-
-
0242560897
-
Substrate specificity of human recombinant mitochondrial deoxyguanosine kinase with cytostatic and antiviral purine and pyrimidine analogs
-
A.H. Sjoberg, L. Wang, S. Eriksson, Substrate specificity of human recombinant mitochondrial deoxyguanosine kinase with cytostatic and antiviral purine and pyrimidine analogs, Mol. Pharmacol. 53 (1998) 270-273.
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 270-273
-
-
Sjoberg, A.H.1
Wang, L.2
Eriksson, S.3
-
26
-
-
0011407354
-
Involvment of Fas ligand/receptor pathway in arabinosylguanine induced apoptosis in leukemic T-cells
-
C.M. Stellrecht, C.O. Rodriguez Jr., V. Gandhi, Involvment of Fas ligand/receptor pathway in arabinosylguanine induced apoptosis in leukemic T-cells, Proc. Am. Assoc. Cancer Res. 43 (2002) 411.
-
(2002)
Proc. Am. Assoc. Cancer Res.
, vol.43
, pp. 411
-
-
Stellrecht, C.M.1
Rodriguez C.O., Jr.2
Gandhi, V.3
-
27
-
-
0032704329
-
Tributyltin-induced apoptosis requires glycolytic adenosine tris-phosphate production
-
H. Stridh, E. Fava, B. Single, P. Nicotera, S. Orrenius, M. Leist, Tributyltin-induced apoptosis requires glycolytic adenosine tris-phosphate production, Chem. Res. Toxicol. 12 (1999) 874-882.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 874-882
-
-
Stridh, H.1
Fava, E.2
Single, B.3
Nicotera, P.4
Orrenius, S.5
Leist, M.6
-
28
-
-
0033590122
-
The role of calcium in pre- and postmitochondrial events in tributyltin-induced T-cell apoptosis
-
H. Stridh, D. Gigliotti, S. Orrenius, I. Cotgreave, The role of calcium in pre- and postmitochondrial events in tributyltin-induced T-cell apoptosis, Biochem. Biophys. Res. Commun. 266 (1999) 460-465.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.266
, pp. 460-465
-
-
Stridh, H.1
Gigliotti, D.2
Orrenius, S.3
Cotgreave, I.4
-
29
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
M.G. Vander Heiden, N.S. Chandel, E.K. Williamson, P.T. Schumacker, C.B. Thompson, Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria, Cell 91 (1997) 627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
30
-
-
0030744833
-
Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells
-
A. Villunger, A. Egle, M. Kos, B.L. Hartmann, S. Geley, R. Kofler, R. Greil, Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells, Cancer Res. 57 (1997) 3331-3334.
-
(1997)
Cancer Res.
, vol.57
, pp. 3331-3334
-
-
Villunger, A.1
Egle, A.2
Kos, M.3
Hartmann, B.L.4
Geley, S.5
Kofler, R.6
Greil, R.7
-
31
-
-
0027381413
-
Substrate specificity of mitochondrial 2′-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine
-
L. Wang, A. Karlsson, E.S. Arner, S. Eriksson, Substrate specificity of mitochondrial 2′-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine, J. Biol. Chem. 268 (1993) 22847-22852.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22847-22852
-
-
Wang, L.1
Karlsson, A.2
Arner, E.S.3
Eriksson, S.4
-
32
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
J. Yang, X. Liu, K. Bhalla, C.N. Kim, A.M. Ibrado, J. Cai, T.I. Peng, D.P. Jones, X. Wang, Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked, Science 275 (1997) 1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.I.7
Jones, D.P.8
Wang, X.9
-
33
-
-
0032531671
-
Phosphorylation of anticancer nucleoside analogs by human mitochondrial deoxyguanosine kinase
-
C. Zhu, M. Johansson, J. Permert, A. Karlsson, Phosphorylation of anticancer nucleoside analogs by human mitochondrial deoxyguanosine kinase, Biochem. Pharmacol. 56 (1998) 1035-1040.
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 1035-1040
-
-
Zhu, C.1
Johansson, M.2
Permert, J.3
Karlsson, A.4
|