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Volumn 178, Issue 6, 2002, Pages 428-436

Validation of Cdc68p as a novel antifungal target

Author keywords

Antifungal target; Candida albicans; CDC68; POB3; Saccharomyces cerevisiae

Indexed keywords

ANTIFUNGAL AGENT; CDC68 PROTEIN; CELL CYCLE PROTEIN; M PROTEIN; POB3 PROTEIN; UNCLASSIFIED DRUG; COPPER SULFATE; FUNGAL PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SPT16 PROTEIN, S CEREVISIAE; TRANSCRIPTION FACTOR;

EID: 0036430010     PISSN: 03028933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00203-002-0470-y     Document Type: Article
Times cited : (4)

References (26)
  • 1
    • 0033514493 scopus 로고    scopus 로고
    • The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance
    • Austin DJ, Kristinsson KG, Anderson RM (1999) The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance. Proc Natl Acad Sci USA 96:1152-1156
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1152-1156
    • Austin, D.J.1    Kristinsson, K.G.2    Anderson, R.M.3
  • 2
    • 0027511893 scopus 로고
    • Secular trends in the epidemiology of nosocomial fungal infections in the United States 1980-1990
    • Beck-Sagué CM, Jarvis WR (1993) Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990. J Infect Dis 167:1247-1251
    • (1993) J Infect Dis , vol.167 , pp. 1247-1251
    • Beck-Sagué, C.M.1    Jarvis, W.R.2
  • 3
    • 0032555659 scopus 로고    scopus 로고
    • Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression
    • Brewster NK, Johnston GC, Singer RA (1998) Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression. J Biol Chem 21:21972-21979
    • (1998) J Biol Chem , vol.21 , pp. 21972-21979
    • Brewster, N.K.1    Johnston, G.C.2    Singer, R.A.3
  • 4
    • 0035027953 scopus 로고    scopus 로고
    • A bipartite yeast SSRP1 analog comprised of Pob3 and Nhp6 proteins modulates transcription
    • Brewster NK, Johnston GC, Singer RA (2001) A bipartite yeast SSRP1 analog comprised of Pob3 and Nhp6 proteins modulates transcription. Mol Cell Biol 21:3491-3502
    • (2001) Mol Cell Biol , vol.21 , pp. 3491-3502
    • Brewster, N.K.1    Johnston, G.C.2    Singer, R.A.3
  • 5
    • 0029966709 scopus 로고    scopus 로고
    • Stable transformation and regulated expression of an inducible reporter construct in Candida albicans using restriction enzyme-mediated integration
    • Brown DH Jr, Slobodkin IV, Kumamoto CA (1996) Stable transformation and regulated expression of an inducible reporter construct in Candida albicans using restriction enzyme-mediated integration. Mol Gen Genet 251:75-80
    • (1996) Mol Gen Genet , vol.251 , pp. 75-80
    • Brown D.H., Jr.1    Slobodkin, I.V.2    Kumamoto, C.A.3
  • 7
    • 0031760928 scopus 로고    scopus 로고
    • The yeast protein complex containing Cdc68 and Pob3 mediates core-promotor repression through the Cdc68 N-terminal domain
    • Evans DRH, Brewster NK, Xu Q, Rowley A, Altheim BA, Johnston GC, Singer RA (1998) The yeast protein complex containing Cdc68 and Pob3 mediates core-promotor repression through the Cdc68 N-terminal domain. Genetics 150:1393-1405
    • (1998) Genetics , vol.150 , pp. 1393-1405
    • Evans, D.R.H.1    Brewster, N.K.2    Xu, Q.3    Rowley, A.4    Altheim, B.A.5    Johnston, G.C.6    Singer, R.A.7
  • 8
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi WA, Irwin MY (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics 134:717-728
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 9
    • 0034905598 scopus 로고    scopus 로고
    • Caspofungin: Pharmacology, safety and therapeutic potential in superficial and invasive fungal infections
    • Groll AH, Walsh TJ (2001) Caspofungin: Pharmacology, safety and therapeutic potential in superficial and invasive fungal infections. Expert Opin Investig Drugs 10:1545-1558
    • (2001) Expert Opin Investig Drugs , vol.10 , pp. 1545-1558
    • Groll, A.H.1    Walsh, T.J.2
  • 11
    • 0028569082 scopus 로고
    • Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog
    • Liu H, Köhler J, Fink GR (1994) Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science 266:1723-1726
    • (1994) Science , vol.266 , pp. 1723-1726
    • Liu, H.1    Köhler, J.2    Fink, G.R.3
  • 12
    • 0025942523 scopus 로고
    • Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promotor function in Saccharomyces cerevisiae
    • Malone EA, Clark CD, Chiang A, Winston F (1991) Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promotor function in Saccharomyces cerevisiae. Mol Cell Biol 11:5710-5717
    • (1991) Mol Cell Biol , vol.11 , pp. 5710-5717
    • Malone, E.A.1    Clark, C.D.2    Chiang, A.3    Winston, F.4
  • 13
    • 0029811986 scopus 로고    scopus 로고
    • TBP-associated factors are not generally required for transcriptional activation in yeast
    • Moqtaderi Z, Bai Y, Poon D, Weil PA, Struhl K (1996) TBP-associated factors are not generally required for transcriptional activation in yeast. Nature 383:188-191
    • (1996) Nature , vol.383 , pp. 188-191
    • Moqtaderi, Z.1    Bai, Y.2    Poon, D.3    Weil, P.A.4    Struhl, K.5
  • 15
    • 0032498273 scopus 로고    scopus 로고
    • FACT, a factor that facilitates elongation through nucleosomes
    • Orphanides G, LeRoy G, Chang C, Luse DS, Reinberg D (1998) FACT, a factor that facilitates elongation through nucleosomes. Cell 92:105-116
    • (1998) Cell , vol.92 , pp. 105-116
    • Orphanides, G.1    LeRoy, G.2    Chang, C.3    Luse, D.S.4    Reinberg, D.5
  • 16
    • 0033566129 scopus 로고    scopus 로고
    • The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins
    • Orphanides G, Wu W, Lane WS, Hampsey M, Reinberg D (1999) The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins. Nature 400: 284-288
    • (1999) Nature , vol.400 , pp. 284-288
    • Orphanides, G.1    Wu, W.2    Lane, W.S.3    Hampsey, M.4    Reinberg, D.5
  • 18
    • 0025999843 scopus 로고
    • CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus
    • Rowley A, Singer RA, Johnston GC (1991) CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus. Mol Cell Biol 11:5718-5726
    • (1991) Mol Cell Biol , vol.11 , pp. 5718-5726
    • Rowley, A.1    Singer, R.A.2    Johnston, G.C.3
  • 19
    • 0029820482 scopus 로고    scopus 로고
    • Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
    • Sanglard D, Ischer F, Monod M, Bille J (1996) Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors. Antimicrobiol Agents Chemother 40:2300-2305
    • (1996) Antimicrobiol Agents Chemother , vol.40 , pp. 2300-2305
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 20
    • 0029045375 scopus 로고
    • The CUG codon is decoded in vivo as serine and not leucine in Candida albicans
    • Santos MAS, Tuite MF (1995) The CUG codon is decoded in vivo as serine and not leucine in Candida albicans. Nucleic Acids Res 23:1481-1486
    • (1995) Nucleic Acids Res , vol.23 , pp. 1481-1486
    • Santos, M.A.S.1    Tuite, M.F.2
  • 23
    • 0032810329 scopus 로고    scopus 로고
    • Computer-aided target selection-prioritizing targets for antifungal drug discovery
    • Spaltmann F, Blunck M, Ziegelbauer K (1999) Computer-aided target selection-prioritizing targets for antifungal drug discovery. Drug Discov Today 4:17-26
    • (1999) Drug Discov Today , vol.4 , pp. 17-26
    • Spaltmann, F.1    Blunck, M.2    Ziegelbauer, K.3
  • 24
    • 77956707736 scopus 로고    scopus 로고
    • Studying essential genes: Generating and using promotor fusions and conditional genes
    • Stark MJR (1998) Studying essential genes: Generating and using promotor fusions and conditional genes. Methods Microbiol 26:83-100
    • (1998) Methods Microbiol , vol.26 , pp. 83-100
    • Stark, M.J.R.1
  • 25
    • 0030920334 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae DNA polymerase catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein
    • Wittmeyer J, Formosa T (1997) The Saccharomyces cerevisiae DNA polymerase catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. Mol Cell Biol 17:4178-4190
    • (1997) Mol Cell Biol , vol.17 , pp. 4178-4190
    • Wittmeyer, J.1    Formosa, T.2
  • 26
    • 0011388935 scopus 로고
    • Screening for novel antifungal agents directed against the basal mRNA transcription apparatus
    • Copping LG, Holloman D, Dixon G (eds). Bios Scientific, Oxford
    • Wobbe CR, Gao N, Bradley JD, Lillie JW (1995) Screening for novel antifungal agents directed against the basal mRNA transcription apparatus. In: Copping LG, Holloman D, Dixon G (eds) Antifungal Agents: Discovery and Mode of Action. Bios Scientific, Oxford, pp 249-255
    • (1995) Antifungal Agents: Discovery and Mode of Action , pp. 249-255
    • Wobbe, C.R.1    Gao, N.2    Bradley, J.D.3    Lillie, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.