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Volumn 32, Issue 10, 2002, Pages 1394-1396

ST2: Marker, activator and regulator of Th2 immunity?

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 0036411758     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2745.2002.01517.x     Document Type: Editorial
Times cited : (8)

References (38)
  • 1
    • 0026610142 scopus 로고
    • Predominant TH2-1ike bronchoalveolar T-lymphocyte population in atopic asthma
    • Robinson DS, Hamid Q, Ying S et al. Predominant TH2-1ike bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992; 326:298-304.
    • (1992) N Engl J Med , vol.326 , pp. 298-304
    • Robinson, D.S.1    Hamid, Q.2    Ying, S.3
  • 3
    • 0031110550 scopus 로고    scopus 로고
    • Successful transfer of late phase T cell eosinophil infiltration in the lung by infusion of helper T cell clones
    • Kaminuma O, Mori A, Ogawa K et al. Successful transfer of late phase T cell eosinophil infiltration in the lung by infusion of helper T cell clones. Am J Respir Cell Mol Biol 1997; 16:448-54.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 448-454
    • Kaminuma, O.1    Mori, A.2    Ogawa, K.3
  • 4
    • 0031918920 scopus 로고    scopus 로고
    • Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice
    • Hogan SP, Koskinen A, Matthaei KI, Young IG, Foster PS. Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice. Am J Respir Crit Care Med 1998; 157:210-8.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 210-218
    • Hogan, S.P.1    Koskinen, A.2    Matthaei, K.I.3    Young, I.G.4    Foster, P.S.5
  • 5
    • 15144358845 scopus 로고    scopus 로고
    • Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics
    • Shi HZ, Xiao CQ, Zhong D et al. Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics. Am J Respir Crit Care Med 1998; 157:204-9.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 204-209
    • Shi, H.Z.1    Xiao, C.Q.2    Zhong, D.3
  • 6
    • 0034755167 scopus 로고    scopus 로고
    • Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-α chain and STAT-6 independently of IL-5 and eotaxin
    • Yang M, Hogan SP, Henry PJ et al. Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-α chain and STAT-6 independently of IL-5 and eotaxin. Am J Respir Cell Mol Biol 2001; 25:522-30.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 522-530
    • Yang, M.1    Hogan, S.P.2    Henry, P.J.3
  • 7
    • 0036007308 scopus 로고    scopus 로고
    • The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells
    • Venkayya R, Lam M, Willkom M, Grunig G, Corry DB, Erie DJ. The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells. Am J Respir Cell Mol Biol 2002; 26:202-8.
    • (2002) Am J Respir Cell Mol BioL , vol.26 , pp. 202-208
    • Venkayya, R.1    Lam, M.2    Willkom, M.3    Grunig, G.4    Corry, D.B.5    Erie, D.J.6
  • 8
    • 0035888720 scopus 로고    scopus 로고
    • Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype?
    • Salvi SS, Babu KS, Holgate ST. Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype? Am J Respir Crit Care Med 2001; 164:1343-6.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1343-1346
    • Salvi, S.S.1    Babu, K.S.2    Holgate, S.T.3
  • 9
    • 0030119169 scopus 로고    scopus 로고
    • T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma
    • Krug N, Madden J, Redington AE et al. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 1996; 14:319-26.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 319-326
    • Krug, N.1    Madden, J.2    Redington, A.E.3
  • 10
    • 0034131336 scopus 로고    scopus 로고
    • Assessment of the Thl/Th2 paradigm in whole blood in atopy and asthma: Increased IFNγ-producing CD8+ T cells in asthma
    • Magnan AO, Mely LG, Camilla CA et al. Assessment of the Thl/ Th2 paradigm in whole blood in atopy and asthma: Increased IFNγ-producing CD8+ T cells in asthma. Am J Respir Crit Care Med 2000; 161:1790-6.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1790-1796
    • Magnan, A.O.1    Mely, L.G.2    Camilla, C.A.3
  • 11
    • 0028432821 scopus 로고
    • Interleukin-4,-5, and -6 and tumor necrosis factor-α in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines
    • Bradding P, Roberts JA, Britten KM et al. Interleukin-4,-5, and -6 and tumor necrosis factor-α in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994; 10:471-80.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 471-480
    • Bradding, P.1    Roberts, J.A.2    Britten, K.M.3
  • 12
    • 0030267703 scopus 로고    scopus 로고
    • Human lung mast cell activation leads to IL-13 mRNA expression and protein release
    • Jaffe JS, Raible DB, Post YJ et al. Human lung mast cell activation leads to IL-13 mRNA expression and protein release. Am J Respir Cell Mol Biol 1996; 15:473-81.
    • (1996) Am J Respir Cell Mol Biol , vol.15 , pp. 473-481
    • Jaffe, J.S.1    Raible, D.B.2    Post, Y.J.3
  • 13
    • 0033863170 scopus 로고    scopus 로고
    • Human mast cells and basophils as sources of cytokines
    • Kobayashi H, Ishizuka T, Okayama Y. Human mast cells and basophils as sources of cytokines. Clin Exp Allergy 2000; 30:1205-12.
    • (2000) Clin Exp Allergy , vol.30 , pp. 1205-1212
    • Kobayashi, H.1    Ishizuka, T.2    Okayama, Y.3
  • 14
    • 0030819040 scopus 로고    scopus 로고
    • Cytokines as targets for the inhibition of eosinophilic inflammation
    • Hogan SP, Foster PS. Cytokines as targets for the inhibition of eosinophilic inflammation. Pharmacol Ther 1997; 74:259-83.
    • (1997) Pharmacol Ther , vol.74 , pp. 259-283
    • Hogan, S.P.1    Foster, P.S.2
  • 15
    • 0033454115 scopus 로고    scopus 로고
    • Interleukin-4 receptor in moderate atopic asthma: A phase I/II randomized, placebo-controlled trial
    • Borish LC, Nelson HS, Lanz MJ et al. Interleukin-4 receptor in moderate atopic asthma: A phase I/II randomized, placebo-controlled trial. Am J Respir Crit Care Med 1999; 160:1816-23.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1816-1823
    • Borish, L.C.1    Nelson, H.S.2    Lanz, M.J.3
  • 16
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response
    • Leckie M J, ten Brinke A, Khan J et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. Lancet 2000; 356:2144-8.
    • (2000) Lancet , vol.356 , pp. 2144-2148
    • Leckie, M.J.1    Ten Brinke, A.2    Khan, J.3
  • 17
    • 0028455633 scopus 로고
    • Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia
    • Gavett HH, Chen X, Finkelman F, Wills-Karp M. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol 1994; 10:587-93.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 587-593
    • Gavett, H.H.1    Chen, X.2    Finkelman, F.3    Wills-Karp, M.4
  • 18
    • 0036223582 scopus 로고    scopus 로고
    • CD4+ T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma
    • Foster PS, Yang M, Herbert C, Kumar RK. CD4+ T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma. Laboratory Invest 2002; 82:455-62.
    • (2002) Laboratory Invest , vol.82 , pp. 455-462
    • Foster, P.S.1    Yang, M.2    Herbert, C.3    Kumar, R.K.4
  • 19
    • 0032480574 scopus 로고    scopus 로고
    • Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma
    • Kon OM, Sihra BS, Compton CH, Leonard TB, Kay AB, Barnes NC. Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma. Lancet 1998; 352:1109-13.
    • (1998) Lancet , vol.352 , pp. 1109-1113
    • Kon, O.M.1    Sihra, B.S.2    Compton, C.H.3    Leonard, T.B.4    Kay, A.B.5    Barnes, N.C.6
  • 20
    • 0033773992 scopus 로고    scopus 로고
    • Attenuation of the allergen-induced late asthmatic reaction by cyclosporin A is associated with inhibition of bronchial eosinophils, interleukin-5, granulocyte macrophage colony-stimulating factor, and eotaxin
    • Khan LN, Kon OM, Macfarlane AJ et al. Attenuation of the allergen-induced late asthmatic reaction by cyclosporin A is associated with inhibition of bronchial eosinophils, interleukin-5, granulocyte macrophage colony-stimulating factor, and eotaxin. Am J Respir Crit Care Med 2000; 162:1377-82.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1377-1382
    • Khan, L.N.1    Kon, O.M.2    Macfarlane, A.J.3
  • 22
    • 0033557718 scopus 로고    scopus 로고
    • Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
    • Randolph DA, Carruthers CJL, Szabo S J, Murphy KM, Chaplin DD. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999; 162:2375-83.
    • (1999) J Immunol , vol.162 , pp. 2375-2383
    • Randolph, D.A.1    Carruthers, C.J.L.2    Szabo, S.J.3    Murphy, K.M.4    Chaplin, D.D.5
  • 23
    • 0032945548 scopus 로고    scopus 로고
    • Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
    • Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999; 103:175-83.
    • (1999) J Clin Invest , vol.103 , pp. 175-183
    • Hansen, G.1    Berry, G.2    DeKruyff, R.H.3    Umetsu, D.T.4
  • 24
    • 0035424185 scopus 로고    scopus 로고
    • IL-13 induces airways hyperreactivity independently of the IL-4Rα chain in the allergic lung
    • Mattes J, Yang M, Siqueira A et al. IL-13 induces airways hyperreactivity independently of the IL-4Rα chain in the allergic lung. J Immunol 2001; 167:1683-92.
    • (2001) J Immunol , vol.167 , pp. 1683-1692
    • Mattes, J.1    Yang, M.2    Siqueira, A.3
  • 25
    • 0028204189 scopus 로고
    • Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor
    • Bergers G, Reikerstorfer A, Braselmann S, Graninger P, Busslinger M. Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. EMBO J 1994; 13:1176-88.
    • (1994) EMBO J , vol.13 , pp. 1176-1188
    • Bergers, G.1    Reikerstorfer, A.2    Braselmann, S.3    Graninger, P.4    Busslinger, M.5
  • 26
    • 0024404517 scopus 로고
    • A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor
    • Tominaga S. A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett 1989; 258:3014.
    • (1989) FEBS Lett , vol.258 , pp. 3014
    • Tominaga, S.1
  • 27
    • 0032212250 scopus 로고    scopus 로고
    • The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors
    • Moritz DR, Rodewald HR, Gheyselinck J, Klemenz R. The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors. J Immunol 1998; 161:4866-74.
    • (1998) J Immunol , vol.161 , pp. 4866-4874
    • Moritz, D.R.1    Rodewald, H.R.2    Gheyselinck, J.3    Klemenz, R.4
  • 28
    • 2642610290 scopus 로고    scopus 로고
    • Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells
    • Xu D, Chan WL, Leung BP et al. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med 1998; 187:787-94.
    • (1998) J Exp Med , vol.187 , pp. 787-794
    • Xu, D.1    Chan, W.L.2    Leung, B.P.3
  • 29
    • 0032499678 scopus 로고    scopus 로고
    • T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
    • Lohning M, Stroehmann A, Coyle AJ et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci USA 1998; 95:6930-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6930-6935
    • Lohning, M.1    Stroehmann, A.2    Coyle, A.J.3
  • 30
    • 0034802499 scopus 로고    scopus 로고
    • Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation
    • Gajewska BU, Swirski FK, Alvarez D et al. Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation. Am J Respir Cell Mol Biol 2001; 25:326-34.
    • (2001) Am J Respir Cell Mol Bio1 , vol.25 , pp. 326-334
    • Gajewska, B.U.1    Swirski, F.K.2    Alvarez, D.3
  • 31
    • 0033523665 scopus 로고    scopus 로고
    • Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
    • Coyle AJ, Lloyd C, Tian J et al. Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J Exp Med 1999; 190:895-902.
    • (1999) J Exp Med , vol.190 , pp. 895-902
    • Coyle, A.J.1    Lloyd, C.2    Tian, J.3
  • 32
    • 0035794272 scopus 로고    scopus 로고
    • Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2) - But not Th1-driven immunopathology
    • Walzl G, Matthews S, Kendall S et al. Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2) - But not Th1-driven immunopathology. J Exp Med 2001; 193:785-92.
    • (2001) J Exp Med , vol.193 , pp. 785-792
    • Walzl, G.1    Matthews, S.2    Kendall, S.3
  • 33
    • 0033570791 scopus 로고    scopus 로고
    • The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function
    • Hoshino K, Kashiwamura S, Kuribayashi K et al. The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med 1999; 190:1541-8.
    • (1999) J Exp Med , vol.190 , pp. 1541-1548
    • Hoshino, K.1    Kashiwamura, S.2    Kuribayashi, K.3
  • 34
    • 0034689033 scopus 로고    scopus 로고
    • T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
    • Townsend M J, Fallon PG, Matthews D J, Jolin HE, McKenzie AN. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med 2000; 191:1069-76.
    • (2000) J Exp Med , vol.191 , pp. 1069-1076
    • Townsend, M.J.1    Fallon, P.G.2    Matthews, D.J.3    Jolin, H.E.4    McKenzie, A.N.5
  • 35
    • 0033933919 scopus 로고    scopus 로고
    • T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis
    • Senn KA, McCoy KD, Maloy KJ et al. T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis. Eur J Immunol 2000; 30:1929-38.
    • (2000) Eur J Immunol , vol.30 , pp. 1929-1938
    • Senn, K.A.1    McCoy, K.D.2    Maloy, K.J.3
  • 37
    • 0035880170 scopus 로고    scopus 로고
    • Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation
    • shikawa K, Kuroiwa K, Tago K et al. Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation. Am J Respir Crit Care Med 2001; 164:277-81.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 277-281
    • Shikawa, K.1    Kuroiwa, K.2    Tago, K.3
  • 38
    • 0036408831 scopus 로고    scopus 로고
    • Expression and function of ST2 gene in a murine model of allergic airway inflammation
    • Oshikawa K, Yanagisawa K, Tominaga S, Sugiyama Y. Expression and function of ST2 gene in a murine model of allergic airway inflammation. Clin Exp Allergy 2002; 32:1520-6.
    • (2002) Clin Exp Allergy , vol.32 , pp. 1520-1526
    • Oshikawa, K.1    Yanagisawa, K.2    Tominaga, S.3    Sugiyama, Y.4


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