-
1
-
-
0026610142
-
Predominant TH2-1ike bronchoalveolar T-lymphocyte population in atopic asthma
-
Robinson DS, Hamid Q, Ying S et al. Predominant TH2-1ike bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992; 326:298-304.
-
(1992)
N Engl J Med
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
Hamid, Q.2
Ying, S.3
-
2
-
-
0030776790
-
Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma
-
Humbert M, Corrigan CJ, Kimmitt P, Till S J, Kay AB, Durham SR. Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am J Respir Crit Care Med 1997; 156:704-8.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 704-708
-
-
Humbert, M.1
Corrigan, C.J.2
Kimmitt, P.3
Till, S.J.4
Kay, A.B.5
Durham, S.R.6
-
3
-
-
0031110550
-
Successful transfer of late phase T cell eosinophil infiltration in the lung by infusion of helper T cell clones
-
Kaminuma O, Mori A, Ogawa K et al. Successful transfer of late phase T cell eosinophil infiltration in the lung by infusion of helper T cell clones. Am J Respir Cell Mol Biol 1997; 16:448-54.
-
(1997)
Am J Respir Cell Mol Biol
, vol.16
, pp. 448-454
-
-
Kaminuma, O.1
Mori, A.2
Ogawa, K.3
-
4
-
-
0031918920
-
Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice
-
Hogan SP, Koskinen A, Matthaei KI, Young IG, Foster PS. Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice. Am J Respir Crit Care Med 1998; 157:210-8.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 210-218
-
-
Hogan, S.P.1
Koskinen, A.2
Matthaei, K.I.3
Young, I.G.4
Foster, P.S.5
-
5
-
-
15144358845
-
Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics
-
Shi HZ, Xiao CQ, Zhong D et al. Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics. Am J Respir Crit Care Med 1998; 157:204-9.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 204-209
-
-
Shi, H.Z.1
Xiao, C.Q.2
Zhong, D.3
-
6
-
-
0034755167
-
Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-α chain and STAT-6 independently of IL-5 and eotaxin
-
Yang M, Hogan SP, Henry PJ et al. Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-α chain and STAT-6 independently of IL-5 and eotaxin. Am J Respir Cell Mol Biol 2001; 25:522-30.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 522-530
-
-
Yang, M.1
Hogan, S.P.2
Henry, P.J.3
-
7
-
-
0036007308
-
The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells
-
Venkayya R, Lam M, Willkom M, Grunig G, Corry DB, Erie DJ. The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells. Am J Respir Cell Mol Biol 2002; 26:202-8.
-
(2002)
Am J Respir Cell Mol BioL
, vol.26
, pp. 202-208
-
-
Venkayya, R.1
Lam, M.2
Willkom, M.3
Grunig, G.4
Corry, D.B.5
Erie, D.J.6
-
8
-
-
0035888720
-
Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype?
-
Salvi SS, Babu KS, Holgate ST. Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype? Am J Respir Crit Care Med 2001; 164:1343-6.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1343-1346
-
-
Salvi, S.S.1
Babu, K.S.2
Holgate, S.T.3
-
9
-
-
0030119169
-
T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma
-
Krug N, Madden J, Redington AE et al. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 1996; 14:319-26.
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, pp. 319-326
-
-
Krug, N.1
Madden, J.2
Redington, A.E.3
-
10
-
-
0034131336
-
Assessment of the Thl/Th2 paradigm in whole blood in atopy and asthma: Increased IFNγ-producing CD8+ T cells in asthma
-
Magnan AO, Mely LG, Camilla CA et al. Assessment of the Thl/ Th2 paradigm in whole blood in atopy and asthma: Increased IFNγ-producing CD8+ T cells in asthma. Am J Respir Crit Care Med 2000; 161:1790-6.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1790-1796
-
-
Magnan, A.O.1
Mely, L.G.2
Camilla, C.A.3
-
11
-
-
0028432821
-
Interleukin-4,-5, and -6 and tumor necrosis factor-α in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines
-
Bradding P, Roberts JA, Britten KM et al. Interleukin-4,-5, and -6 and tumor necrosis factor-α in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994; 10:471-80.
-
(1994)
Am J Respir Cell Mol Biol
, vol.10
, pp. 471-480
-
-
Bradding, P.1
Roberts, J.A.2
Britten, K.M.3
-
12
-
-
0030267703
-
Human lung mast cell activation leads to IL-13 mRNA expression and protein release
-
Jaffe JS, Raible DB, Post YJ et al. Human lung mast cell activation leads to IL-13 mRNA expression and protein release. Am J Respir Cell Mol Biol 1996; 15:473-81.
-
(1996)
Am J Respir Cell Mol Biol
, vol.15
, pp. 473-481
-
-
Jaffe, J.S.1
Raible, D.B.2
Post, Y.J.3
-
13
-
-
0033863170
-
Human mast cells and basophils as sources of cytokines
-
Kobayashi H, Ishizuka T, Okayama Y. Human mast cells and basophils as sources of cytokines. Clin Exp Allergy 2000; 30:1205-12.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 1205-1212
-
-
Kobayashi, H.1
Ishizuka, T.2
Okayama, Y.3
-
14
-
-
0030819040
-
Cytokines as targets for the inhibition of eosinophilic inflammation
-
Hogan SP, Foster PS. Cytokines as targets for the inhibition of eosinophilic inflammation. Pharmacol Ther 1997; 74:259-83.
-
(1997)
Pharmacol Ther
, vol.74
, pp. 259-283
-
-
Hogan, S.P.1
Foster, P.S.2
-
15
-
-
0033454115
-
Interleukin-4 receptor in moderate atopic asthma: A phase I/II randomized, placebo-controlled trial
-
Borish LC, Nelson HS, Lanz MJ et al. Interleukin-4 receptor in moderate atopic asthma: A phase I/II randomized, placebo-controlled trial. Am J Respir Crit Care Med 1999; 160:1816-23.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1816-1823
-
-
Borish, L.C.1
Nelson, H.S.2
Lanz, M.J.3
-
16
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response
-
Leckie M J, ten Brinke A, Khan J et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. Lancet 2000; 356:2144-8.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
Ten Brinke, A.2
Khan, J.3
-
17
-
-
0028455633
-
Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia
-
Gavett HH, Chen X, Finkelman F, Wills-Karp M. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol 1994; 10:587-93.
-
(1994)
Am J Respir Cell Mol Biol
, vol.10
, pp. 587-593
-
-
Gavett, H.H.1
Chen, X.2
Finkelman, F.3
Wills-Karp, M.4
-
18
-
-
0036223582
-
CD4+ T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma
-
Foster PS, Yang M, Herbert C, Kumar RK. CD4+ T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma. Laboratory Invest 2002; 82:455-62.
-
(2002)
Laboratory Invest
, vol.82
, pp. 455-462
-
-
Foster, P.S.1
Yang, M.2
Herbert, C.3
Kumar, R.K.4
-
19
-
-
0032480574
-
Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma
-
Kon OM, Sihra BS, Compton CH, Leonard TB, Kay AB, Barnes NC. Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma. Lancet 1998; 352:1109-13.
-
(1998)
Lancet
, vol.352
, pp. 1109-1113
-
-
Kon, O.M.1
Sihra, B.S.2
Compton, C.H.3
Leonard, T.B.4
Kay, A.B.5
Barnes, N.C.6
-
20
-
-
0033773992
-
Attenuation of the allergen-induced late asthmatic reaction by cyclosporin A is associated with inhibition of bronchial eosinophils, interleukin-5, granulocyte macrophage colony-stimulating factor, and eotaxin
-
Khan LN, Kon OM, Macfarlane AJ et al. Attenuation of the allergen-induced late asthmatic reaction by cyclosporin A is associated with inhibition of bronchial eosinophils, interleukin-5, granulocyte macrophage colony-stimulating factor, and eotaxin. Am J Respir Crit Care Med 2000; 162:1377-82.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1377-1382
-
-
Khan, L.N.1
Kon, O.M.2
Macfarlane, A.J.3
-
22
-
-
0033557718
-
Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
-
Randolph DA, Carruthers CJL, Szabo S J, Murphy KM, Chaplin DD. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999; 162:2375-83.
-
(1999)
J Immunol
, vol.162
, pp. 2375-2383
-
-
Randolph, D.A.1
Carruthers, C.J.L.2
Szabo, S.J.3
Murphy, K.M.4
Chaplin, D.D.5
-
23
-
-
0032945548
-
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
-
Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999; 103:175-83.
-
(1999)
J Clin Invest
, vol.103
, pp. 175-183
-
-
Hansen, G.1
Berry, G.2
DeKruyff, R.H.3
Umetsu, D.T.4
-
24
-
-
0035424185
-
IL-13 induces airways hyperreactivity independently of the IL-4Rα chain in the allergic lung
-
Mattes J, Yang M, Siqueira A et al. IL-13 induces airways hyperreactivity independently of the IL-4Rα chain in the allergic lung. J Immunol 2001; 167:1683-92.
-
(2001)
J Immunol
, vol.167
, pp. 1683-1692
-
-
Mattes, J.1
Yang, M.2
Siqueira, A.3
-
25
-
-
0028204189
-
Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor
-
Bergers G, Reikerstorfer A, Braselmann S, Graninger P, Busslinger M. Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. EMBO J 1994; 13:1176-88.
-
(1994)
EMBO J
, vol.13
, pp. 1176-1188
-
-
Bergers, G.1
Reikerstorfer, A.2
Braselmann, S.3
Graninger, P.4
Busslinger, M.5
-
26
-
-
0024404517
-
A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor
-
Tominaga S. A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett 1989; 258:3014.
-
(1989)
FEBS Lett
, vol.258
, pp. 3014
-
-
Tominaga, S.1
-
27
-
-
0032212250
-
The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors
-
Moritz DR, Rodewald HR, Gheyselinck J, Klemenz R. The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors. J Immunol 1998; 161:4866-74.
-
(1998)
J Immunol
, vol.161
, pp. 4866-4874
-
-
Moritz, D.R.1
Rodewald, H.R.2
Gheyselinck, J.3
Klemenz, R.4
-
28
-
-
2642610290
-
Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells
-
Xu D, Chan WL, Leung BP et al. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med 1998; 187:787-94.
-
(1998)
J Exp Med
, vol.187
, pp. 787-794
-
-
Xu, D.1
Chan, W.L.2
Leung, B.P.3
-
29
-
-
0032499678
-
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
-
Lohning M, Stroehmann A, Coyle AJ et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci USA 1998; 95:6930-5.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6930-6935
-
-
Lohning, M.1
Stroehmann, A.2
Coyle, A.J.3
-
30
-
-
0034802499
-
Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation
-
Gajewska BU, Swirski FK, Alvarez D et al. Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation. Am J Respir Cell Mol Biol 2001; 25:326-34.
-
(2001)
Am J Respir Cell Mol Bio1
, vol.25
, pp. 326-334
-
-
Gajewska, B.U.1
Swirski, F.K.2
Alvarez, D.3
-
31
-
-
0033523665
-
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
-
Coyle AJ, Lloyd C, Tian J et al. Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J Exp Med 1999; 190:895-902.
-
(1999)
J Exp Med
, vol.190
, pp. 895-902
-
-
Coyle, A.J.1
Lloyd, C.2
Tian, J.3
-
32
-
-
0035794272
-
Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2) - But not Th1-driven immunopathology
-
Walzl G, Matthews S, Kendall S et al. Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2) - But not Th1-driven immunopathology. J Exp Med 2001; 193:785-92.
-
(2001)
J Exp Med
, vol.193
, pp. 785-792
-
-
Walzl, G.1
Matthews, S.2
Kendall, S.3
-
33
-
-
0033570791
-
The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function
-
Hoshino K, Kashiwamura S, Kuribayashi K et al. The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med 1999; 190:1541-8.
-
(1999)
J Exp Med
, vol.190
, pp. 1541-1548
-
-
Hoshino, K.1
Kashiwamura, S.2
Kuribayashi, K.3
-
34
-
-
0034689033
-
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
-
Townsend M J, Fallon PG, Matthews D J, Jolin HE, McKenzie AN. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med 2000; 191:1069-76.
-
(2000)
J Exp Med
, vol.191
, pp. 1069-1076
-
-
Townsend, M.J.1
Fallon, P.G.2
Matthews, D.J.3
Jolin, H.E.4
McKenzie, A.N.5
-
35
-
-
0033933919
-
T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis
-
Senn KA, McCoy KD, Maloy KJ et al. T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis. Eur J Immunol 2000; 30:1929-38.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1929-1938
-
-
Senn, K.A.1
McCoy, K.D.2
Maloy, K.J.3
-
36
-
-
0033855772
-
Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation
-
Lambrecht BN, De Veerman M, Coyle AJ, Gutierrez-Ramos JC, Thielemans K, Pauwels RA. Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation. J Clin Invest 2000; 106:551-9.
-
(2000)
J Clin Invest
, vol.106
, pp. 551-559
-
-
Lambrecht, B.N.1
De Veerman, M.2
Coyle, A.J.3
Gutierrez-Ramos, J.C.4
Thielemans, K.5
Pauwels, R.A.6
-
37
-
-
0035880170
-
Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation
-
shikawa K, Kuroiwa K, Tago K et al. Elevated soluble ST2 protein levels in sera of patients with asthma with an acute exacerbation. Am J Respir Crit Care Med 2001; 164:277-81.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 277-281
-
-
Shikawa, K.1
Kuroiwa, K.2
Tago, K.3
-
38
-
-
0036408831
-
Expression and function of ST2 gene in a murine model of allergic airway inflammation
-
Oshikawa K, Yanagisawa K, Tominaga S, Sugiyama Y. Expression and function of ST2 gene in a murine model of allergic airway inflammation. Clin Exp Allergy 2002; 32:1520-6.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 1520-1526
-
-
Oshikawa, K.1
Yanagisawa, K.2
Tominaga, S.3
Sugiyama, Y.4
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