Molecular mechanisms of neuronal cell death: Implications for nuclear factors responding to cAMP and phorbol esters

Molecular and Cellular Neuroscience

Volumn 21, Issue 1, 2002, Pages 1-14

  Vyas, Sheela ^a   Biguet, Nicole Faucon ^b   Michel, Patrick P ^b   Monaco, Lucia ^c   Foulkes, Nicholas S ^c   Evan, Gerard I ^d   Sassone Corsi, Paolo ^c   Agid, Yves ^b  

^a INSERM   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIMYCIN; CASPASE 3; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NERVE GROWTH FACTOR; NUCLEAR FACTOR; PHORBOL ESTER DERIVATIVE; PROTEIN BAX; PROTEIN C FOS; PROTEIN P21; PROTEIN P53; TAU PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL LEVEL; CELL SURVIVAL; CONCENTRATION RESPONSE; CYCLIC AMP RESPONSIVE ELEMENT; DOSE TIME EFFECT RELATION; GENE INDUCTION; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0036396844     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2002.1170     Document Type: Article

References (54)

1. Agid, Y., and Blin, J. (1987). Nerve cell death in degenerative diseases of the central nervous system: Clinical aspects. CIBA Found. Symp. 126: 3-29.
2. Aloyz, R. S., Bamji, S. X., Pozniak, C. D., Toma, J. G., Atwal, J., Kaplan, D. R., and Miller, F. D. (1998). p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. J. Cell Biol. 143: 1691-1703.
3. Andrews, N. C., and Faller, D. V. (1991). A rapid micropreparation technique for extraction of DNA binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19: 2499.
4. Angalde, P., Vyas, S., Hirsch, E. C., and Agid, Y. (1997). Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. Histol. Histopathol. 12: 603-610.
5. Arnould, T., Vankoningsloo, S., Renard, P., Houbion, A., Ninane, N., Demazy, C., Remacle, J., and Raes, M. (2002). CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation. EMBO J. 21: 53-63.
6. Braak, H., and Braak, E. (1994). Morphological criteria for the recognition of Alzehimer's disease and the distribution pattern of cortical changes related to this disorder. Neurobiol. Aging 15: 355-356.
7. Buttyan, R., Zakeri, Z., Lockshin, R., and Woglemuth, D. (1988). Cascade induction of c-fos, c-myc and heat shock 70 K transcripts during regression of the ventral prostate gland. Mol. Endocrinol. 2: 650-657.
8. Calne, D. B., and Peppard, R. F. (1987). Aging of the nigrostriatal pathway in humans. Can. J. Neurol. Sci. 14: 424-427.
9. Choi, D. W. (1995). Calcium: Still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18: 58-60.
10. Chomczynski, P., and Sacchi, N. (1987). Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
11. Collota, F., Polentarutti, N., Sironi, M., and Mantovani, A. (1992). Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J. Biol. Chem. 267: 18278-18283.
12. Dean, M., Levine, R. A., Ran, W., Kindy, M. S., Sonenshein, G. E., and Camisi, J. (1986). Regulation of c-myc transcriptional and mRNA abundance by serum growth factors and cell contact. J. Biol. Chem. 261: 9161.
13. deGroot, R. P., Hertog, J. D., Vanderheede, J. R., Goris, J., and Sassone-Corsi, P. (1993). Multiple and cooperative phophorylation events regulate the CREM activator function. EMBO J. 12: 3903-3911.
14. Eizenberg, O., Faber-Elman, A., Gottleib, E., Oren, M., Rotter, V., and Schwartz, M. (1996). p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells. Mol. Cell. Biol. 16: 5178-5185.
15. Evan, G., and Littlewood, T. (1998). A matter of life and cell death. Science 281: 1317-1322.
16. Evan, G. I., and Vousden, K. H. (2001). Proliferation, cell cycle and apoptosis in cancer. Nature 411: 342-348.
17. Evan, G. I., Wyllie, A. H., Gilbert, C. S., Littlewood, T. D., Land, H., Brooks, M., Waters, C. M., Penn, L. Z., and Hancock, D. C. (1992). Induction of apoptosis in fibroblasts by c-myc protein. Cell 69: 119-128.
18. Feng, Z., Joos, H. J., Vallan, C., Mulbauer, R., Altermatt, H. J., and Jaggi, R. (1998). Apoptosis during castration induced regression of the prostate is Fos dependent. Oncogene 17: 2593-2600.
19. Fortin, A., Cregan, S. P., MacLaurin, J. G., Kushwaha, N., Hickman, E. S., Thompson, C. S., Hakim, A., Albert, P. R., Cecconi, F., Helin, K., Park, D. S., and Slack, R. S. (2001). APAF-1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J. Cell Biol. 15: 207-216.
20. Foulkes, N., and Sassone-Corsi, P. (1992). More is better: Activators and repressors from the same gene. Cell 68: 411-414.
21. Giebler, H. A., Lemasson, I., and Nyborg, J. K. (2000). p53 recruitment of CREB binding protein mediated through phosphorylated CREB: A novel pathway of tumor suppressor regulation. Mol. Cell. Biol. 20: 4849-4858.
22. Ginty, D. D., Bonni, A., and Greenberg, M. (1994). Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylaton of CREB. Cell 77: 713-725.
23. Glucksman, A. (1951). Cell death in normal vertebrate ontogeny. Biol. Rev. 26: 59-68.
24. Gollapudi, L., and Oblinger, M. M. (1999). Stable transfections of PC12 cells with estrogen receptor (ERalpha): Protective effects on cell survival after serum deprivation. J. Neurosci. Res. 56: 99-108.
25. Gonzalez, G. A., Menzel, P., Leonard, J., Fisher, W. H., and Montminy, M. R. (1991). Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol. Cell. Biol. 11: 1306-1312.
26. Habener, J. (1990). Cyclic AMP-responsive elemnt binding proteins: A cornuocopia of transcription factors. Mol. Endocrinol. 4: 1087-1094.
27. Hafezi, F., Stenbach, J. P., Marti, A., Munz, K., Wang, Z.-Q., Wagner, E. F., Aguzzi, A., and Remy, C. (1997). The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo. Nat. Med. 3: 346-349.
28. Harrington, E. A., Bennet, M. R., Fanisi, A., and Evan, G. I. (1994). c-myc induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13: 3286-3295.
29. Karin, M., Zheng-Gang, L., and Zandi, E. (1997). AP1 function and regulation. Curr. Opin. Cell Biol. 9: 240-246.
30. Kuan, C. Y., Yang, D. D., Roy, D. R. S., Davis, R. J., Rakic, P., and Flavell, R. A. (1999). The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron 22: 667-676.
31. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J., and Woodgett, J. R. (1994). The stress-activated protein kinase subfamily of c-jun kinases. Nature 369: 156-160.
32. Lalli, E., and Sassone-Corsi, P. (1994). Signal transduction and gene regulation: The nuclear response to cAMP. J. Biol. Chem. 269: 17359-17362.
33. Lee, W., Mithcell, P., and Tjian, R. (1987). Purified transcription factor AP-1 interacts with TPA-inducible enhancer element. Cell 49: 741-752.
34. Lewin, G. R., and Barde, Y. A. (1996). Physiology of the neurotro-phins. Annu. Rev. Neurosci. 19: 289-317.
35. Lonze, B. E., Riccio, A., Cohen, S., and Ginty, D. D. (2002). Apoptosis, axonal growth defects and degeneration of peripheral neurons in mice lacking CREB. Neuron 34: 371-385.
36. McConkey, D. J., and Orrenius, S. (1997). The role of calcium in the regulation of apoptosis. Biochem. Biophys. Res. Commun. 239: 357-366.
37. Michel, P. P., Vyas, S., and Agid, Y. (1995). Synergistic differentiation by chronic exposure to cyclic AMP and nerve growth factor renders PC12 cells totally dependent upon trophic support for survival. Eur. J. Neurosci. 7: 577-586.
38. Michel, P. P., Vyas, S., Anglade, P., Ruberg, M., and Agid, Y. (1994). Morphological and molecular response of differentiated PC12 cells to calcium stress. Eur. J. Neurosci. 6: 577-586.
39. Molina, C. A., Foulkes, N., Lalli, E., and Sassone-Corsi, P. (1993). Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor. Cell 75: 875-886.
40. Montminy, M. R., and Bilezikjian, L. M. (1987). Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 328: 175-178.
41. Namura, S., Zhu, J., Fink, K., Enders, M., Srinivasan, A., Tomaselli, K., Yuan, J., and Moskowitz, M. (1998). Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J. Neurosci. 18: 3659-3668.
42. Peng, X., Greene, L. A., Kaplan, D. R., and Stephens, R. M. (1995). Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis. Neuron 15: 395-406.
43. Preston, G. A., Lyon, T. T., Yin, Y., Lang, J. E., Solomon, G., Annab, L., Srinivasan, D. G., Alcorta, D. A., and Barrett, J. C. (1996). Induction of apoptosis by c-Fos protein. Mol. Cell Biol. 16: 211-218.
44. Sanchez, I., Xu, C.-J., Juo, P., Kakizaka, A., Blenis, J., and Yuan, J. (1998). Caspase-8 is required for cell death induced by expanded polyglutamine repeats. Neuron 22: 623-633.
45. Sassone-Corsi, P., Visvader, J., Ferland, L., Mellon, P. L., and Verma, I. (1988). Induction of proto-oncogene c-fos transcription through the adenylate cyclase pathway: Characterization of a cAMP-responsive element. Genes Dev. 2: 1529-1538.
46. Shaulian, E., and Karin, M. (2001). AP-1 in cell proliferation and survival Oncogene 20: 2390-2400.
47. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252: 1427-1430.
48. Smeyne, R., Vendrell, J., M., Hayward, M., Baker, S. J., Miao, G. G., Schilling, K., Robertson, L., Curran, T., and Morgan, J. I. (1993). Continous c-fos expression precedes programmed cell death in vivo. Nature 363: 166-169.
49. Tandan, R., and Bradley, W. G. (1985). Amyotrophic lateral sclerosis: Part, clinical features, pathology and ethical issues in management. Ann. Neurol. 18: 271-280.
50. Treisman, R. (1992) The serum response element. Trends Biochem. Sci. 17: 423-426.
51. Vyas, S., Javoy-Agid, F., Herrero, M.-T., Strada, O., Hibner, U., and Agid, Y. (1997). Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders. J. Neurochem. 69: 223-231.
52. Wang, Z. Q., Grigoriadis, A. E., Mohle-Steinlein, U., and Wagner, E. F. (1991). A novel target for c-fos induced oncogenesis: Development of chondrogenic tumors in embryonic stem cell chimeras. EMBO J. 10: 2437-2450.
53. Wrighton, C., and Busslinger, M. (1993). Direct transcriptional stimulation of the ornithine decarboxylase gene by Fos in PC12 cells but not in fibroblasts. Mol. Cell. Biol. 13: 4657-4669.
54. Zheng, P., Herch, E. C., Damie, P., Duyckaerts, C., and Javoy-Agid, F. (1992). c-Fos protein-like immunoreactivity in the human brain and over-expression in the patients with Alzheimer's disease. Neuro-science 46: 9-21.