Stable transfection of PC12 cells with estrogen receptor (ERα): Protective effects of estrogen on cell survival after serum deprivation

Journal of Neuroscience Research

Volumn 56, Issue 1, 1999, Pages 99-108

  Gollapudi, Lakshmi ^a   Oblinger, Monica M M ^a,b  

^a The Chicago Medical College   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

Apoptosis; Estrogen estradiol; Steroid receptors

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ESTROGEN ACTIVITY; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; MITOSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERUM;

ANIMALS; APOPTOSIS; CELL DIVISION; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; DNA REPLICATION; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; FEMALE; IN SITU NICK-END LABELING; PC12 CELLS; RATS; RECEPTORS, ESTROGEN; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; UTERUS;

EID: 0033118387     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990401)56:1<99::AID-JNR13>3.0.CO;2-G     Document Type: Article

References (36)

1. Agrati P, Garnier M, Patrone C. Pollio G, Santagati S, Vegeto E, Maggi A. 1997. SK-ER3 neuroblastoma cells as a model for the study of estrogen influence on neural cells. Brain Res Bull 44:519-523.
2. Batistatou A, Greene LA. 1991. Aurintricarboxylic acid rescues PCI2 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J Cell Biol 115:461-471.
3. Batistatou A. Greene LA. 1993. Internucleosomal DNA cleavage and neuronal cell survival/death. J Cell Biol 122:523-532.
4. Behl C, Widmunn M, Trapp T, Holsboer F. 1995. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophysical Res Comm 216:473-482.
5. Bishop J, Simpkins JW. 1994. Estradiol treatment increases viability of glioma and neuroblastoma cells in vitro. Mol Cell Neurosci 5:303-308.
6. Blaustein JD. 1993. Estrogen receptor immunoreactivity in rat brain: rapid effects of estradiol injection. Endocrinology 132:1218-1224.
7. Chomcyznski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
8. Chowen JA. Torres-Aleman I, Garcia-Segura LM. 1992. Trophic effects of estradiol on fetal rat hypothalamic neurons. Neuroendocrinology 56:895-901.
9. DonCarlos L. 1996. Developmental profile and regulation of estrogen receptor (ER) mRNA expression in the preoptic area of prenatal rats. Dev Brain Res 94:224-233.
10. Gollapudi L. Neet KN. 1997. Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine. J Neurosci Res 49:461-474.
11. Green PS, Bishop J. Simpkins JW. 1997. 17-alpha estradiol exerts neuroprotective effects on SK-N-SH cells. J Neurosci 17:511-515.
12. Green PS, Gridley KE, Simpkins JW. 1998. Nuclear estrogen receptor-independent neuroprotection hy estratricnes: a novel interaction with glutathione. Neuroscience 84:7-10.
13. Greene GL, Sobel NB, King WJ, Jensen EV. 1984. Immunochemical studies of estrogen receptors. J Steroid Biochem 20:51-56.
14. Greene LA. 1978. Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium J Cell Biol 78:747-755.
15. Greene LA, Tischler AS. 1976. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. PNAS 73:2424-2428.
16. Hirata S, Osada T, Hirai M, Hagihara K, Kato J. 1992. Expression of estrogen receptor in the rat brain: detection of its mRNA using reverse transcription-polymerase chain reaction. J Steroid Biochem Mol Biol 41:583-587.
17. Honjo H, Tamura T. Matsumoto Y. Kawata M, Ogino Y, Tanaka K, Yamamoto T, Veda S, Okada H. 1992. Estrogen as a growth factor to central nervous cells. Estrogen promotes development of acetylcholinesterase positive basal forebrain neurons transplanted in the anterior eye chamber. J Steroid Biochem Mol Biol 41:633-635.
18. Honjo H, Tanaka K, Kashiwagi T, Urabe M, Okada H, Hayashi M, Hayashi K. 1995. Senile dementia-Alzheimer's type and estrogen. Hormone Metab Res 27:204-207.
19. Ignar Trowbridge DM, Nelson KR, Bidwell MC, Curtis SW, Washburn TF. McLachlan JA. Korach K. 1992. Coupling of dual signaling pathways: epidermal growth factor action involves phosphorylation of the estrogen receptor. PNAS 89:4658-4662.
20. Johnson EM, Deckworth TL. 1993. Molecular mechanisms of developmental neuronal death. Ann Rev Neurosci 16:31-46.
21. Keefe D, Garcia-Segura LM, Naftolin F. 1994. New insights into estrogen action on the brain. Neurobiol Aging 15:495-497.
22. Koike S, Sakai M, Muramatusu M. 1987. Molecular cloning and characterization of rat estrogen receptor cDNA. Nucl Acid Res 15:2499-2513.
23. Levenson AS, Jordan VC. 1994. Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines J Steroid Biochem Mol Biol 51:229-239.
24. Lippman ME, Bolan G. Huff K. 1976. The effect of estrogens and anti-estrogens on hormone-responsive breast cancer in long term culture. Cancer Res 36:4595-4601.
25. Lustig RH, Hua P, Yu W, Ahmad FJ, Baas PW. 1994. An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC 12 cells. J Neurosci 14:3945-3957.
26. Parker MG. 1993. Structure and function of the oestrogen receptor. J Neuroendocrin 5:223-228.
27. Quarmby VE. Korach KS. 1984. The influence of 17β-estradiol on patterns of cell division in the uterus. Endocrinology 114:694-699.
28. Rudkin BB, Lazarovici P, Levi B, Abe Y, Fujita K, Guroff G. 1989. Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation. EMBO J 8:3319-3325.
29. Rukenstein A. Rydel RE. Greene LA. 1991. Multiple agents rescue PC12 cells from serum-free cell death by translation-and transcription-independent mechanisms. J Neurosci 11:2552-2563.
30. Sahlin L, Eriksson H. 1996. Influence of blockers for the estrogen receptor (ER) and Type 1 IGF-receptor on the levels of ER, ER mRNA and IGF-1 mRNA in the rat uterus. J Steroid Biochem Mol Biol 58:359-365.
31. Snider WD. 1994. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-638.
32. Sohrabji F, Greene LA, Miranda RC, Toran-Allerand CD. 1994. Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells. J Neurobiol 25:974-988.
33. Tang MX, Jacobs D, Stern Y. Marder K, Schofield P, Gurland H, Andrews H, Mayeux R. 1996. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 348:429-432.
34. Tsai M. O'Malley BW. 1994. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Ann Rev Biochem 63:451-486.
35. White E. 1996. Life, death, and the pursuit of apoptosis. Genes Dev 10:1-15.
36. Woolley CS. 1997. Estradiol increases the sensitivity of hippocampal CA1 pyramidal cells to NMDA receptor-mediated synaptic input: correlation with dendritic spine density. J Neurosci 17:1848-1855.