Proteasome inhibitors regulate tyrosine phosphorylation of IRS-1 and insulin signaling in adipocytes

Biochemical and Biophysical Research Communications

Volumn 296, Issue 5, 2002, Pages 1257-1263

  Rondinone, Cristina M ^a   Kramer, Deborah ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Adipocytes; Glucose transport; IRS 1; Lactacystin; PKB; Proteasome inhibitors; Tyrosine phosphorylation

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CALPASTATIN; CALPEPTIN; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; LACTACYSTIN; PHOSPHATASE; PROTEASOME INHIBITOR; PROTEIN KINASE B; TYROSINE; TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; GLUCOSE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ACETYLCYSTEINE; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENZYME INHIBITORS; GLUCOSE; INSULIN; KINETICS; LEUPEPTINS; MICE; MULTIENZYME COMPLEXES; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 0036389560     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02083-1     Document Type: Article

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