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Volumn 76, Issue 9, 2002, Pages 517-522

Skin toxicokinetics of mustard gas in the guinea pig: Effect of hypochlorite and safety aspects

Author keywords

Decontamination; Hypochlorite; Mustard gas; Topical exposure; Toxicokinetics

Indexed keywords

HYPOCHLORITE; MUSTARD GAS; WATER;

EID: 0036378794     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0362-6     Document Type: Article
Times cited : (32)

References (33)
  • 1
    • 0001544960 scopus 로고
    • The mode of penetration of the skin by mustard gas
    • Cullumbine H (1946) The mode of penetration of the skin by mustard gas. Br J Dermatol 58:291-294
    • (1946) Br J Dermatol , vol.58 , pp. 291-294
    • Cullumbine, H.1
  • 2
    • 0029931420 scopus 로고    scopus 로고
    • Toxicology and pharmacology of the chemical warfare agent sulfur mustard
    • Dacre JC, Goldman M (1996) Toxicology and pharmacology of the chemical warfare agent sulfur mustard. Pharmacol Rev 48:289-326
    • (1996) Pharmacol Rev , vol.48 , pp. 289-326
    • Dacre, J.C.1    Goldman, M.2
  • 4
    • 0016699688 scopus 로고
    • Biochemical and physiological parameters on the skin surface of healthy test persons: A contribution towards the interpretation of the results obtained by a screening program
    • Gloor M, Kionke M, Friederich HC (1975) Biochemical and physiological parameters on the skin surface of healthy test persons: a contribution towards the interpretation of the results obtained by a screening program. Arch Dermatol Forsch 252:317-330
    • (1975) Arch Dermatol Forsch , vol.252 , pp. 317-330
    • Gloor, M.1    Kionke, M.2    Friederich, H.C.3
  • 5
    • 0027942256 scopus 로고
    • Hypochlorite solution as a decontaminant in sulfur mustard contaminated skin defects in the euthymic hairless guinea pig
    • Gold MB, Bongiovanni R, Scharf BA, Greshman VC, Woodward CL (1994) Hypochlorite solution as a decontaminant in sulfur mustard contaminated skin defects in the euthymic hairless guinea pig. Drug Chem Toxicol 17:499-527
    • (1994) Drug Chem Toxicol , vol.17 , pp. 499-527
    • Gold, M.B.1    Bongiovanni, R.2    Scharf, B.A.3    Greshman, V.C.4    Woodward, C.L.5
  • 6
    • 0030904340 scopus 로고    scopus 로고
    • L-Oxothiazolidine 4-carboxylate pretreatment of isolated human peripheral blood lymphocytes reduces sulfur mustard cytotoxicity
    • Gross CL, Giles KC, Smith WJ (1997) L-Oxothiazolidine 4-carboxylate pretreatment of isolated human peripheral blood lymphocytes reduces sulfur mustard cytotoxicity. Cell Biol Toxicol 13:167-173
    • (1997) Cell Biol Toxicol , vol.13 , pp. 167-173
    • Gross, C.L.1    Giles, K.C.2    Smith, W.J.3
  • 7
    • 0031742351 scopus 로고    scopus 로고
    • Diisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard
    • Lindsay CD, Hambrook JL (1998) Diisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard. Hum Exp Toxicol 17:606-612
    • (1998) Hum Exp Toxicol , vol.17 , pp. 606-612
    • Lindsay, C.D.1    Hambrook, J.L.2
  • 8
    • 0030730317 scopus 로고    scopus 로고
    • Monoisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard
    • Lindsay CD, Hambrook JL, Lailey AF (1997) Monoisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard. Hum Exp Toxicol 16:636-644
    • (1997) Hum Exp Toxicol , vol.16 , pp. 636-644
    • Lindsay, C.D.1    Hambrook, J.L.2    Lailey, A.F.3
  • 10
    • 0032248590 scopus 로고    scopus 로고
    • Protective efficacy of calcium channel blockers in sulphur mustard poisoning
    • Mazumder PK, Sugendran K, Vijayaraghavan R (1998) Protective efficacy of calcium channel blockers in sulphur mustard poisoning. Biomed Environ Sci 11:363-369
    • (1998) Biomed Environ Sci , vol.11 , pp. 363-369
    • Mazumder, P.K.1    Sugendran, K.2    Vijayaraghavan, R.3
  • 11
    • 0026766122 scopus 로고
    • The determination and prevention of cytotoxic effects induced in human lymphocytes by the alkylating agent 2,2'-dichlorodiethyl sulfide (sulfur mustard, HD)
    • Meier HL, Johnson JB (1992) The determination and prevention of cytotoxic effects induced in human lymphocytes by the alkylating agent 2,2'-dichlorodiethyl sulfide (sulfur mustard, HD). Toxicol Appl Pharmacol 113:234-239
    • (1992) Toxicol Appl Pharmacol , vol.113 , pp. 234-239
    • Meier, H.L.1    Johnson, J.B.2
  • 16
    • 0028784398 scopus 로고
    • Toxicokinetics of topical sulfur mustard penetration, disposition, and vascular toxicity in isolated perfused porcine skin
    • Riviere JE, Brooks JD, Williams PL, Monteiro-Riviere NA (1995) Toxicokinetics of topical sulfur mustard penetration, disposition, and vascular toxicity in isolated perfused porcine skin. Toxicol Appl Pharmacol 135:25-34
    • (1995) Toxicol Appl Pharmacol , vol.135 , pp. 25-34
    • Riviere, J.E.1    Brooks, J.D.2    Williams, P.L.3    Monteiro-Riviere, N.A.4
  • 17
    • 0031739128 scopus 로고    scopus 로고
    • Characterization of the protective effects of L-nitroarginine methyl ester (L-NAME) against the toxicity of sulphur mustard in vitro
    • Sawyer TW (1998) Characterization of the protective effects of L-nitroarginine methyl ester (L-NAME) against the toxicity of sulphur mustard in vitro. Toxicology 131:21-32
    • (1998) Toxicology , vol.131 , pp. 21-32
    • Sawyer, T.W.1
  • 18
    • 0033105581 scopus 로고    scopus 로고
    • Synergistic protective effects of selected arginine analogues against sulphur mustard toxicity in neuron culture
    • Sawyer TW (1999) Synergistic protective effects of selected arginine analogues against sulphur mustard toxicity in neuron culture. Toxicol Appl Pharmacol 155:169-176
    • (1999) Toxicol Appl Pharmacol , vol.155 , pp. 169-176
    • Sawyer, T.W.1
  • 19
    • 0034652191 scopus 로고    scopus 로고
    • Effects of selected arginine analogues on sulphur mustard toxicity in human and hairless guinea pig skin keratinocytes
    • Sawyer TW, Risk D (2000) Effects of selected arginine analogues on sulphur mustard toxicity in human and hairless guinea pig skin keratinocytes. Toxicol Appl Pharmacol 163:75-85
    • (2000) Toxicol Appl Pharmacol , vol.163 , pp. 75-85
    • Sawyer, T.W.1    Risk, D.2
  • 20
    • 0032140654 scopus 로고    scopus 로고
    • L-Thiocitrulline: A potent protective agent against the toxicity of sulphur mustard in vitro
    • Sawyer TW, Hancock JR, D'Agostino PA (1998) L-Thiocitrulline: a potent protective agent against the toxicity of sulphur mustard in vitro. Toxicol Appl Pharmacol 151:340-346
    • (1998) Toxicol Appl Pharmacol , vol.151 , pp. 340-346
    • Sawyer, T.W.1    Hancock, J.R.2    D'Agostino, P.A.3
  • 21
    • 0026322043 scopus 로고
    • Medical defense against blistering chemical warfare agents
    • Smith WJ, Dunn MA (1991) Medical defense against blistering chemical warfare agents. Arch Dermatol 127:1207-1213
    • (1991) Arch Dermatol , vol.127 , pp. 1207-1213
    • Smith, W.J.1    Dunn, M.A.2
  • 22
  • 23
    • 0028905042 scopus 로고
    • Sulfur mustard: Its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term health effects, and new developments for protection and therapy
    • Smith KJ, Hurst CG, Moeller RB, Skelton, HG, Sidell FR (1995b) Sulfur mustard: its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term health effects, and new developments for protection and therapy. J Am Acad Dermatol 32:765-776
    • (1995) J Am Acad Dermatol , vol.32 , pp. 765-776
    • Smith, K.J.1    Hurst, C.G.2    Moeller, R.B.3    Skelton, H.G.4    Sidell, F.R.5
  • 25
    • 0003633755 scopus 로고    scopus 로고
    • National Academy Press, Washington, D.C.
    • US Department of Health and Human Services (1996) Guide for the Care and Use of Laboratory Animals. National Academy Press, Washington, D.C.
    • (1996) Guide for the Care and Use of Laboratory Animals
  • 26
    • 0028043423 scopus 로고
    • Cysteine esters protect cultured rodent lung slices from sulphur mustard
    • Wilde PE, Upshall DG (1994) Cysteine esters protect cultured rodent lung slices from sulphur mustard. Hum Exp Toxicol 13:743-748
    • (1994) Hum Exp Toxicol , vol.13 , pp. 743-748
    • Wilde, P.E.1    Upshall, D.G.2
  • 27
    • 0026100493 scopus 로고
    • Toxicology of mustard gas
    • Wormser U (1991) Toxicology of mustard gas. Trends Pharmacol Sci 12:164-167
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 164-167
    • Wormser, U.1
  • 28
    • 0031825565 scopus 로고    scopus 로고
    • Early topical treatment with povidone-iodine ointment reduces, and sometimes prevents, skin damage following heat stimulus
    • Wormser U (1998) Early topical treatment with povidone-iodine ointment reduces, and sometimes prevents, skin damage following heat stimulus. Burns 24:383
    • (1998) Burns , vol.24 , pp. 383
    • Wormser, U.1
  • 29
    • 0031052420 scopus 로고    scopus 로고
    • Protective effect of povidone-iodine ointment against skin lesions induced by sulphur and nitrogen mustards and by non-mustard vesicants
    • Wormser U, Brodsky B, Green BS, Arad-Yellin R, Nyska A (1997) Protective effect of povidone-iodine ointment against skin lesions induced by sulphur and nitrogen mustards and by non-mustard vesicants. Arch Toxicol 71:165-170
    • (1997) Arch Toxicol , vol.71 , pp. 165-170
    • Wormser, U.1    Brodsky, B.2    Green, B.S.3    Arad-Yellin, R.4    Nyska, A.5
  • 30
    • 0000258371 scopus 로고    scopus 로고
    • Protective effect of povidone iodine ointment against skin lesions induced by chemical and thermal stimuli
    • Wormser U, Brodsky B, Green BS, Arad-Yellin R, Nyska A (2000a) Protective effect of povidone iodine ointment against skin lesions induced by chemical and thermal stimuli. J Appl Toxicol 20:S183-S185
    • (2000) J Appl Toxicol , vol.20
    • Wormser, U.1    Brodsky, B.2    Green, B.S.3    Arad-Yellin, R.4    Nyska, A.5
  • 31
    • 0034669043 scopus 로고    scopus 로고
    • Topical iodine preparation as therapy against sulfur mustard-induced skin lesions
    • Wormser U, Sintov A, Brodsky B, Nyska A (2000b) Topical iodine preparation as therapy against sulfur mustard-induced skin lesions. Toxicol Appl Pharmacol 169:33-39
    • (2000) Toxicol Appl Pharmacol , vol.169 , pp. 33-39
    • Wormser, U.1    Sintov, A.2    Brodsky, B.3    Nyska, A.4
  • 32
    • 0028948216 scopus 로고
    • Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin
    • Yourick JJ, Dawson JS, Mitcheltree LW (1995) Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin. J Appl Toxicol 15:133-138
    • (1995) J Appl Toxicol , vol.15 , pp. 133-138
    • Yourick, J.J.1    Dawson, J.S.2    Mitcheltree, L.W.3
  • 33
    • 0030818144 scopus 로고    scopus 로고
    • Comparison of integrins in human skin, pig skin, and perfused skin: An in vitro skin toxicology model
    • Zhang Z, Monteiro-Riviere NA (1997) Comparison of integrins in human skin, pig skin, and perfused skin: an in vitro skin toxicology model. J Appl Toxicol 17:247-253
    • (1997) J Appl Toxicol , vol.17 , pp. 247-253
    • Zhang, Z.1    Monteiro-Riviere, N.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.