Comparison of integrins in human skin, pig skin, and perfused skin: An in vitro skin toxicology model

Journal of Applied Toxicology

Volumn 17, Issue 4, 1997, Pages 247-253

  Zhang, Zili ^a   Monteiro Riviere, Nancy A ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Human skin; In vitro; Integrins; Isolated perfused skin; Pig skin; Vesication; Wound healing

Indexed keywords

INTEGRIN; MUSTARD GAS;

ANIMAL TISSUE; ARTICLE; BLISTER; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KERATINOCYTE; MODEL; NONHUMAN; PRIORITY JOURNAL; SKIN TOXICITY; SWINE; TISSUE PERFUSION; WOUND HEALING;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD29; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; BLISTER; HUMANS; IMMUNOHISTOCHEMISTRY; INTEGRIN ALPHA3BETA1; INTEGRIN ALPHA6BETA4; INTEGRINS; MUSTARD GAS; ORGAN CULTURE TECHNIQUES; PERFUSION; RECEPTORS, COLLAGEN; SKIN; SPECIES SPECIFICITY; SWINE; WOUND HEALING;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0030818144     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(199707)17:4<247::AID-JAT437>3.0.CO;2-S     Document Type: Article

References (33)

1. R O. Hynes, Integrins, a family of cell surface receptor, Cell 48, 549-555 (1989).
2. E. Rouslahti, Control of cell motility and tumor invasion by extracellular matrix interactions. Br. J. Cancer 66, 239-242 (1992).
3. K R Gehlsen, L. Dillner, E Engvall and E. Ruoslahti, The human laminin receptor is a member of the integrin family of cell adhesion receptors. Science 241, 1228-1229 (1988).
4. E. A. Wayner and W G Carter, Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique α and common β subunits. J. Cell Biol. 105, 1873-1884 (1987).
5. W. G. Carter, E. A Wayner, T S. Bouchard and P Kaur, The role of integrins α2β1 and α3β1 in cell-cell and cell-substrate adhesion of human epidermal cells. J. Cell Biol. 110, 1387-1404 (1990)
6. W. G. Carter, P. Kaur, S G. Gil, P J. Gahr and E. A. Wayner, Distinct functions for integrin α3β1 in focal adhesions and α6β4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: Relation to hemidesmosomes. J Cell Biol. 111, 3141-3157 (1990).
7. A. Cavani, G Zambruno, A. Marconi, V Manca, M. Marchetti and A Giannetti, Distinctive integrin expression in newly forming epidermis during wound healing in humans J Invest. Dermatol 1, 600-604 (1993)
8. R N Tamura, C Rozzo, L. Starr, J Chambers, L F Reichardt, H M Cooper and V Quaranta, Epithelial integrin α6β4 Complete primary structure of α6 and variant forms of β4 J Cell Biol 111, 1593-1604 (1990)
9. V Quaranta, Epithelial integrins. Cell Differ. Dev 32, 361-366 (1990)
10. M A Kurpakus, V Quaranta and JCR Jones, Surface relocation of α6β4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing. J. Cell Biol. 115, 1737-1750 (1991).
11. H. Michalaki, M J. Staquet, A. Cerri, E. Berti, P. Roche, P. Machado and J. F. Nicolas, Expression of the α6β4 integrin in lesional skin differentiates bullous pemphigoid (BP) from epidermolysis bullosa acquisita (EBA). J. Invest. Dermatol 98, 204-208 (1992).
12. V. A. Venning, J. Allen, J. D. Aplin, G. Kirtschig and F. Wojnarowska, The distribution of α6β4 integrins in lesional and non-lesional skin in bullous pemphigoid. Br. J. Dermatol. 127, 103-111 (1992).
13. R. J. Phillips, J. D. Aplin and B D. Lake, Antigenic expression of integrin α6β4 in junctional epidermolysis bullosa. Histopathology 24, 571-576 (1994).
14. S. G Gill, T. A. Brown, M. C. Ryan and W. G. Carter, Junctional epidermolysis bullosis: Defects in expression of epiligrin/nicein/kalinin and integrin β4 that inhibit hemidesmosome formation J. Invest Dermatol. 103, 31S-38S (1994).
15. J R. King, B. P. Peters and N A Monteiro-Riviere, Laminin in the cutaneous basement membrane as a potential target in lewisite vesication. Toxicol. Appl. Pharmacol. 126, 164-173 (1994).
16. Z. Zhang, B. P. Peters and N A Monteiro-Riviere, Assessment of sulfur mustard interaction with basement membrane components Cell Biol. Toxicol. 11, 89-101 (1995)
17. J. E. Riviere and N A Monteiro-Riviere, The isolated perfused porcine skin flap as an in vitro model for percutaneous absorption and cutaneous toxicology. CRC Crit. Rev Toxicol 21, 329-344 (1991)
18. N A Monteiro-Riviere, Specialized technique: The isolated perfused porcine skin flap (IPPSF) In Methods for Skin Absorption, ed by B. W. Kemppainen and W. G Reifenrath pp 175-189 CRC Press. Boca Raton, FL (1990).
19. J R. King, J. E Riviere and N A Monteiro-Riviere, Characterization of lewisite toxicity in isolated perfused porcine skin. Toxicol. Appl. Pharmacol. 116, 189-201 (1992).
20. N. A Monteiro-Riviere and A. O. Inman, Indirect immunohistochemistry and immunoelectron microscopy distribution of eight epidermal-dermal junction epitopes in the pig and in isolated perfused skin treated with bis (2-chloroethyl) Sulfide. Toxicol Pathol 23, 313-323 (1995).
21. N A. Monteiro-Riviere and M W. Stromberg, Ultrastructure of the integument of the domestic pig (Sus scrofa) from one through fourteen weeks of age. Zentralbl. Vet. Med. C. Anat. Histol. Embryol 14, 97-115 (1985).
22. D. L. Bissett and J. F. McBride, Use of the domestic pig as an animal model of human dry skin In Models in Dermatology I, ed. by H. I. Maibach and N. J Lowe, pp 159-168. Karger, Basel (1985).
23. I A. King, A. Tabiowo, P R Fryer, P. E. Purkis and I. Leigh, Basal cell glycoprotein in pig epidermis closely resembles the β1 subunit of the integrin family of cell adhesion molecules. J. Invest. Dermatol. 97, 501-505 (1991).
24. E. Ruoslahti, Integrins. J. Clin. Invest. 87, 1-5 (1991).
25. S. M. Albelda and C A. Buck, Integrins and other cell adhesive molecules. FASEB J. 4, 2868-2880 (1990).
26. H. Larjava, J. Peltonen, S. K. Akiyama, S S. Yamada, H. R. Gralnick, J. Uitto and K. M. Yamada, Novel function for β1 integrins in keratinocyte cell-cell interactions. J. Cell Biol. 110, 803-815 (1990).
27. M A Kurpakus, V. Quaranta and J C K. Jones, Surface relocation of α6β4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing. J. Cell Biol. 115, 1737-1750 (1991).
28. J C Jones, M. A. Kurpakus, H. M. Cooper and V. Quaranta, A function for the integrin α6β4 in the hemidesmosome Cell Regul 2, 427-438 (1991).
29. M DeLuca, R. N Tamura and S. Kajiji, Polarized integrin mediates human keratinocyte adhesion to basal lamina. Proc. Natl Acad. Sci. USA 87, 6888-6892 (1990).
30. M. Korhonen, J. Ylanne, L. Laitinen, H. M. Cooper, V. Quaranta and I. Virtanen, Distribution of α1-α6 integrin subunits in human developing and term placenta. Lab. Invest 65, 347-356 (1991).
31. Z. Zhang, J. E. Riviere and N. A. Monteiro-Riviere, Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide, and indomethacin on sulfur mustard-treated isolated perfused porcine skin. Chem. Biol. Interact. 96, 249-262 (1995).
32. Z. Zhang, J. E. Riviere and N. A Monteiro-Riviere, Topical sulfur mustard induces changes in prostaglandins and interleukin-1, in isolated perfused porcine skin. In Vitro Toxicol. 8, 149-158 (1995).
33. N. A. Monteiro-Riviere, Use of the isolated perfused skin model in dermatotoxicology. In Vitro Toxicol. 5, 219-233 (1992).