p53 gene family p51(p63)-encoded, secondary transactivator p51b(TAp63α) occurs without forming an immunoprecipitable complex with MDM2, but responds to genotoxic stress by accumulation

Experimental Cell Research

Volumn 276, Issue 2, 2002, Pages 194-200

  Okada, Yohei ^a   Osada, Motonobu ^a   Kurata, Shun Ichi ^a   Sato, Shingo ^a   Aisaki, Ken Ichi ^a   Kageyama, Yukio ^a   Kihara, Kazunori ^a   Ikawa, Yoji ^a,b   Katoh, Iyoko ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

Accumulation; DNA damage; Genotoxic stress; MDM2; p21waf1; p51; p53; p63; Proteasome; Tumor suppressor

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BLEOMYCIN; DACTINOMYCIN; ETOPOSIDE; MESSENGER RNA; OKADAIC ACID; PROTEIN ANTIBODY; PROTEIN MDM2; PROTEIN P21; PROTEIN P51A; PROTEIN P51B; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; GENE EXPRESSION; IMMUNOPRECIPITATION; MOLECULAR WEIGHT; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRESS; ULTRAVIOLET C RADIATION; WESTERN BLOTTING;

EID: 0036352550     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2002.5535     Document Type: Article

References (40)

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6. p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
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