Loss of nuclear expression of the p33ING1b inhibitor of growth protein in childhood acute lymphoblastic leukaemia

Journal of Clinical Pathology

Volumn 55, Issue 8, 2002, Pages 596-601

  Nouman, G S ^a   Anderson, J J ^a   Wood, K M ^a   Lunec, J ^a   Hall, A G ^a   Reid, M M ^b   Angus, B ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P33 ING1B; PROTEIN P53; UNCLASSIFIED DRUG;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER SURVIVAL; CELL CYCLE; CHILD; CHILDHOOD LEUKEMIA; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TP53 GENE; TUMOR SUPPRESSOR GENE;

ADOLESCENT; CELL CYCLE PROTEINS; CELL NUCLEUS; CHILD; CHILD, PRESCHOOL; CYTOPLASM; DNA-BINDING PROTEINS; FEMALE; FOLLOW-UP STUDIES; GENES, TUMOR SUPPRESSOR; HUMANS; INFANT; INFANT, NEWBORN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROGNOSIS; PROTEINS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0036342646     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.55.8.596     Document Type: Article

References (37)

1. Suppression of the novel growth inhibitor p33 (ING1) promotes neoplastic transformation
2. Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene (ING1)
3. Localization of the candidate tumor suppressor gene ING1 to human chromosome 13q34
4. Genomic organization of a tumor growth inhibitor gene ING1
5. Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas
6. Suppression of the novel growth inhibitor p33 (ING1) promotes neoplastic transformation
7. Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: Characterization of tissue-specific ING1 transcripts and a homologue gene
8. p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1
9. Monoclonal antibodies raised to products of the ING1 tumour suppressor gene locus
10. Extension of the replicative life span of human diploid fibroblasts by inhibition of the p33(ING1) candidate tumor suppressor
11. A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis
12. Molecular aspects of the relationship between cancer and aging: Tumor suppressor activity during cellular senescence
13. Inactivation of p33(ING1) tumor suppressor affects the function of the cell cycle "checkpoints" and stability of the genome
14. The candidate tumour suppressor p33(ING1) cooperates with p53 in cell growth control
15. Decreased expression of p33ING1 mRNA in lymphoid malignancies
16. Reduced expression of p33 (ING1) and the relationship with p53 expression in human gastric cancer
17. Diminished expression of ING1 mRNA and the correlation with p53 expression in breast cancers
18. Suppression of ING1 expression in sporadic breast cancer
19. The candidate tumour suppressor gene, ING1, is retained in colorectal carcinomas
20. Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions
21. Mutational analysis of the candidate tumor suppressor gene ING1 in Indian oral squamous cell carcinoma
22. Sequencing of ING1 tumour suppressor gene cDNAs generated From mRNA recovered from normal and neoplastic cell lines
23. High-dose infusional doxorubicin and cyclophosphamide: A feasibility study of tandem high-dose chemotherapy cycles without stem cell support
24. Epidemiology of acute leukemia in children and adults
25. Critical study of prognostic factors in childhood acute lymphoblastic leukaemia: Differences in outcome are poorly explained by the most significant prognostic variables
26. Fifty years of studies of the biology and therapy of childhood leukemia
27. Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia
28. Mice lacking p21 cip1/waf1 undergo normal development, but are defective in G1 checkpoint control
29. The p53 tumour suppressor gene
30. Myeloperoxidase positive acute lymphoblastic leukemia cell lines, NALM-30, NALM-31 and NALM-32, carrying Philadelphia chromosome with biphenotypic characteristics
31. Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood
32. Improved survival with early intensification: Combined results from the Medical Research Council childhood ALL randomised trials, UKALL X and UKALL XI
33. A "quickscore" method for immunohistochemical semiquantitation: Validation for oestrogen receptor in breast carcinomas
34. UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences
35. Comparative assessment of expression of the inhibitor of growth 1 (ING1) gene in normal amd neoplastic tissues
36. Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy
37. Topoisomerase IIα and IIβ expression in childhood acute lymphoblastic leukaemia: Relation to prognostic factors and clinical outcome