UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences

Nucleic Acids Research

Volumn 29, Issue 10, 2001, Pages 2052-2058

  Scott, Michelle ^a   Boisvert, François Michel ^a   Vieyra, Diego ^a   Johnston, Randal N ^a   Bazett Jones, David P ^a   Riabowol, Karl ^a,b  

^a UNIVERSITY OF CALGARY   (Canada)

^b Heritage Medical Research Building ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; NUCLEAR PROTEIN;

APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; GENE MAPPING; GENE OVEREXPRESSION; GENE SEQUENCE; GENE TARGETING; HUMAN; HUMAN CELL; MUTANT; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

ANIMALIA;

EID: 0035872871     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.10.2052     Document Type: Article

References (33)

1. Toyama, T., Iwase, H., Watson, P., Muzik, H., Saettler, E., Magliocco, A., DiFrancesco, L., Forsyth, P., Garkavtsev, I., Kobayashi, S. and Riabowol, K. (1999) Suppression of ING1 expression in sporadic breast cancer. Oncogene, 18, 5187-5193.
2. ING1 and the relationship with p53 expression in human gastric cancer. Cancer Lett., 62, 157-162.
3. ING1 mRNA in lymphoid malignancies. Am. J. Hematol., 62, 118-119.
4. Gunduz, M., Ouchida, M., Fukushima, K., Hanafusa, H., Etani, T., Nishioka, S., Nishizaki, K. and Shimizu, K. (2000) Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas. Cancer Res., 60, 3143-3146.
5. ING1 promotes neoplastic transformation. Nat. Genet., 14, 415-420.
6. Helbing, C.C., Veillette, C., Riabowol, K., Johnston, R.N. and Garkavtsev, I. (1997) A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis. Cancer Res., 57, 1255-1258.
7. ING1 with p53 drastically augments apoptosis in gliomas. Cancer Res., 59, 5521-5528.
8. Jager, D., Stockert, E., Scanlan, M., Gure, A.O., Jager, E., Knuth, A., Old, L.J. and Chen, Y.-T. (1999) Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene. Cancer Res., 59, 6197-6204.
9. ING1 associated with histone acetyl transferase in vivo. Mol. Cell. Biol., 20, 3807-3816.
10. McMahon, S.B., Van Buskirk, H.A., Dugan, K.A., Copeland, T.D. and Cole, M.D. (1998) The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell, 94, 363-374.
11. Antoine, M., Reimers, K., Dickson, C. and Kiefer, P. (1997) Fibroblast growth factor 3, a protein with dual subcellular localization, is targeted to the nucleus and nucleolus by the concerted action of two nuclear localization signals and a nucleolar retention signal. J. Biol. Chem., 272, 29475-29481.
12. Galcheva-Gargova, Z., Gangwani, L., Konstantinov, K.N., Mikrut, M., Theroux, S.J., Enoch, T. and Davis, R.J. (1998) The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells. Mol. Biol., Cell, 9, 2963-2971.
13. Pederson, T. (1998) Growth factors in the nucleolus? J. Cell Biol., 143, 279-281.
14. Stegh, A., Schickling, O., Ehrel, A., Scaffidi, C., Peterhansel, C., Hofmann, T.G., Grummt, I., Krammer, P.H. and Peter, M. (1998) DEDD, a novel death effector domain-containing protein, targeted to the nucleolus. EMBO J., 17, 5974-5986.
15. Hatanaka, M. (1990) Discovery of the nucleolar targeting signal. Bioessays, 12, 143-148.
16. Stauber, R.H. and Pavlakis, G.N. (1998) Intracellular trafficking and interactions of the HIV-1 Tat protein. Virology, 252, 126-136.
17. Zhang, Y. and Xiong, Y. (1999) Mutations inhuman ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Mol. Cell, 3, 579-591.
18. Weber, J.D., Taylor, L.J., Roussel, M.F., Sherr, C.J. and Bar-Sagi, D. (1999) Nucleolar Arf sequesters Mdm2 and activates p53. Nat. Cell Biol., 1, 20-26.
19. Garkavtsev, I., Demetrick, D. and Riabowol, K. (1997) Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene (ING1). Cytogenet. Cell Genet., 76, 176-178.
20. Henderson, J.E., Amizuka, N., Warshawshy, H., Biasotto, D., Lanske, B.M.K., Goltzman, D. and Karaplis, A.C. (1995) Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death. Mol. Cell. Biol., 15, 4064-4075.
21. Christians, F.C. and Hanawalt, P.C. (1993) Lack of transcription-coupled repair in mammalian ribosomal RNA genes. Biochemistry, 32, 10512-10518.
22. Kaufmann, S., Mesner, P., Samejima, K., Tone, S. and Earnshaw, W. (2000) Measuring apoptosis and apoptosis-induced endonucleases. Methods Enzymol., 322, 3-47.
23. Boisvert, F.-M., Hendzel, M.H. and Bazett-Jones, D.P. (2000) Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA. J. Cell Biol., 148, 283-292.
24. Boland, D., Olineck, V., Bonnefin, P., Vieyra, D., Parr, E. and Riabowol, K. (2000) A panel of Cab antibodies recognize endogenous and ectopically expressed ING1 protein. Hybridoma, 19, 161-166.
25. Cheung, K.-J., Jr, Bush, J.A and Li, G. (2000) Expression of the novel tumour suppressor p33ING1 is independent of p53. Br. J. Cancer, 83, 1468-1472.
26. Lu, X. and Lane, D.P. (1993) Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndrome? Cell, 75, 765-778.
27. ing1 cooperates with p53 in cell growth control. Nature, 391, 295-298.
28. Schmidt-Zachmann, M.S. and Nigg, E.A. (1993) Protein localization to the nucleolus: a search for targeting domains in nucleolin. J. Cell Sci., 105, 799-806.
29. Jarrous, N., Wolenski, J.S., Wesolowski, D., Lee, C. and Altman, S. (1999) Localization in the nucleolus and coiled bodies of protein subunits of the ribonucleoprotein ribonuclease P.J. J. Cell Biol., 146, 559-571.
30. Balajee, A.S., May, A. and Bohr, V.A. (1999) DNA repair of pyrimidine dimers and 6-4 photoproducts in the ribosomal DNA. Nucleic Acids Res., 27, 2511-2520.
31. Andera, L. and Wasylyk, B. (1997) Transcription abnormalities potentiate apoptosis of normal human fibroblasts. Mol. Med., 3, 852-863.
32. Ma, D., Lawless, D. and Riabowol, K. (1999) Correction and addition to ING1 isoform sequences. Nat. Genet., 23, 73.
33. Saito, A., Furukawa, T., Fukushige, S., Koyama, S., Hoshi, M., Hayashi, Y. and Horii, A. (2000) p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1. J. Hum. Genet., 45, 177-181.